Now showing items 321-330 of 383
The Nitric Oxide Donor DETA-NONOate Decreases Matrix Metalloproteinase-9 Expression and Activity in Rat Aortic Smooth Muscle and Abdominal Aortic Explants
(Springer-Verlag; Annals of Vascular Surgery Inc., 2006-01)
Our objective was to examine the role of an exogenous nitric oxide (NO) donor, DETA-NONOate (DETA), on matrix metalloproteinase (MMP)-9, MMP-2, and tissue inhibitor of matrix metalloproteinases (TIMP)-1 expression and ...
Clinical implications of the new biology in the development of melanoma vaccines
(John Wiley & Sons, Inc., 1999-04)
There has been a resurgence in clinical research of vaccine therapies, particularly for the treatment of melanoma. The renewed interest in this field is attributable to an increased understanding regarding the immune ...
Sentinel lymph node biopsy for breast cancer: How many nodes are enough?
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-01)
Introduction Sentinel lymph node (SLN) biopsy using blue dye and radioisotope often results in the removal of multiple SLNs. We sought to determine whether there is a point where the surgeon can terminate the procedure ...
Myocardial Engineering in Vivo: Formation and Characterization of Contractile, Vascularized Three-Dimensional Cardiac Tissue
(Mary Ann Liebert, Inc., publishers, 2005-05-01)
Engineering cardiac tissue in three dimensions is limited by the ability to supply nourishment to the cells in the center of the construct. This limits the radius of an in vitro engineered cardiac construct to approximately ...
Cholecystokinin receptor antagonism of stimulated pancreatic and gastric secretion
(Elsevier, 1989-11)
The effects of cholecystokinin receptor antagonist, dipentyl-3,4-dichloroproglumide (DDP), on stimulated pancreatic and gastric secretion were studied in the rat. DDP dose-dependently inhibited cholecystokinin-stimulated ...
Elevated intracranial pressure associated with hypermetabolism in isolated head trauma
(Springer-Verlag, 1988-09)
Both metabolic rate and protein catabolism are known to increase following severe head trauma, but the etiology of this hypermetabolism is unknown. To further investigate the problem, we studied the metabolism of 17 patients ...
Global Expression Profiles in Human Normal and Aneurysmal Abdominal Aorta Based on Two Distinct Whole Genome Microarray Platforms
(Blackwell Publishing Inc, 2006-11)
Abdominal aortic aneurysms (AAA) are the thirteenth cause of death in the United States. The etiology of the disease is yet largely unknown, although several environmental risk factors (e.g., smoking) have been identified ...
Extra-adrenal and metastatic pheochromocytoma: The role of 131 I meta-iodobenzylguanidine ( 131 I MIBG) in localization and management
(Springer-Verlag; Springer International, 1984-08)
From June, 1980, to August, 1983, 131 I MIBG scintiscans were performed in 353 patients with suspected pheochromocytomas. Extra-adrenal pheochromocytomas were identified in 15 of 18 patients who at operation were proven ...
A proteomic analysis of Psychrobacter articus 273-4 adaptation to low temperature and salinity using a 2-D liquid mapping approach
(WILEY-VCH Verlag, 2007-02)
Psychrobacter 273-4 was isolated from a 20 000–40 000–year-old Siberian permafrost core, which is characterized by low temperature, low water activity, and high salinity. To explore how 273-4 survives in the permafrost ...
Immunologic response to cryoablation of breast cancer
(Kluwer Academic Publishers; Springer, 2005-03)
Purpose .With improvements in breast imaging and image-guided interventions, there is interest in ablative techniques for breast cancer. Cryosurgery initiates inflammation and leaves tumor-specific antigens intact, which ...