Now showing items 331-340 of 383
Differential effects of cAMP and cGMP on in vitro epidermal cell growth
(Elsevier, 1979-04)
Primary keratinocyte cultures free of dermal fibroblasts were used to investigate the effect of varying cyclic AMP (cAMP) concentrations on epidermal cell function. Addition of 10-3, 10-4 or 10-5 M dibutyryl cAMP to plated ...
Constitutive activation of pp125fak in newly isolated human breast cancer cell lines
(Kluwer Academic Publishers; Springer Science+Business Media, 1999-03)
Our laboratory has developed twelve human breast cancer cell lines from primary and metastatic sites. In this report we demonstrate that eight of eight breast cancer cell lines examined exhibit constitutively tyrosine ...
Interleukin-6 changes tight junction permeability and intracellular phospholipid content in a human enterocyte cell culture model
(Springer-Verlag, 2003-07)
Proinflammatory cytokines and secretory phospholipase A 2 (sPLA 2 ) are elevated in patients with inflammatory bowel disease (IBD). We previously reported that the proinflammatory cytokine IL-6 increased the expression of ...
Pulmonary endothelial cell ATP depletion following intestinal ischemia
(Elsevier, 1992-06)
Multiple organ failure (MOF) is known to follow systemic inflammatory mediator activation associated with intestinal ischemia--reperfusion injury. In particular, the pulmonary microvasculature appears to be susceptible to ...
The role of the surgeon in the management of melanoma.
(2006)
While multimodality therapy has become the standard for most solid tumors, the mainstay of therapy for melanoma remains surgical. This includes not only early stage disease, but advanced melanoma as well. The surgical ...
Racial and Gender Trends in the Use of Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries Between 1997 and 2003
(Blackwell Publishing Ltd, 2009-03)
Refinements in Mathematical Models to Predict Aneurysm Growth and Rupture
(Blackwell Publishing Inc, 2006-11)
The growth of aneurysms and eventually their likelihood of rupture depend on the determination of the stress and strain within the aneurysm wall and the exact reproduction of its geometry. A numerical model is developed ...
Effects of glucagon and prostacyclin in acute occlusive and postocclusive canine mesenteric ischemia
(Elsevier, 1984-06)
Effects of glucagon and prostacyclin (PGI2) were studied in anesthetized dogs during sequential occlusive and postocclusive mesenteric ischemia induced by 90 min of tourniquet stenosis of the superior mesenteric artery ...