Now showing items 61-70 of 83
Pancreatic cancer stem cells and relevance to cancer treatments
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05-01)
Pancreatic cancer continues to be a malignancy with few therapeutic options. The majority of patients that present for an evaluation have locally advanced or metastatic disease that is incurable by surgical approaches. ...
Attenuation of Experimental Aortic Aneurysm Formation in P-Selectin Knockout Mice
(Blackwell Publishing Inc, 2006-11)
The aim of this study was to determine the role of P-selectin, an adhesion molecule found on the surface of activated platelets and endothelial cells during experimental aortic aneurysm formation. Infrarenal abdominal ...
Α-Lactosylceramide as a Novel “Sugar-Capped” CD1d Ligand for Natural Killer T Cells: Biased Cytokine Profile and Therapeutic Activities
(WILEY-VCH Verlag, 2008-06-16)
The invariant natural killer T cells (iNKT) cells have emerged as an important regulator of immunity to infection, cancer, and autoimmune diseases. They can be activated by glycolipids that bind to CD1d. The most effective ...
Intercellular calcium waves in cultured enteric glia from neonatal guinea pig
(Wiley Subscription Services, Inc., A Wiley Company, 2003-05)
Enteric glia are important participants in information processing in the enteric nervous system. However, intercellular signaling mechanisms in enteric glia remain largely unknown. We postulated that intercellular calcium ...
Comprehensive analysis of proteins of pH fractionated samples using monolithic LC/MS/MS, intact MW measurement and MALDI-QIT-TOF MS
(John Wiley & Sons, Ltd., 2007-03)
A comprehensive platform that integrates information from the protein and peptide levels by combining various MS techniques has been employed for the analysis of proteins in fully malignant human breast cancer cells. The ...
A continuous flow probe method for on‐line introduction of liquid samples for detection by laser desorption with resonant two‐photon ionization in supersonic beam mass spectrometry
(The American Institute of Physics, 1991-04)
A continuous flow probe is used as a direct inlet source for injection of liquid samples into a time‐of‐flight (TOF) mass spectrometer. The direct liquid inlet is coupled to laser desorption as a means of rapidly vaporizing ...
Global Expression Profiles in Human Normal and Aneurysmal Abdominal Aorta Based on Two Distinct Whole Genome Microarray Platforms
(Blackwell Publishing Inc, 2006-11)
Abdominal aortic aneurysms (AAA) are the thirteenth cause of death in the United States. The etiology of the disease is yet largely unknown, although several environmental risk factors (e.g., smoking) have been identified ...
A proteomic analysis of Psychrobacter articus 273-4 adaptation to low temperature and salinity using a 2-D liquid mapping approach
(WILEY-VCH Verlag, 2007-02)
Psychrobacter 273-4 was isolated from a 20 000–40 000–year-old Siberian permafrost core, which is characterized by low temperature, low water activity, and high salinity. To explore how 273-4 survives in the permafrost ...
Differential effects of cAMP and cGMP on in vitro epidermal cell growth
(Elsevier, 1979-04)
Primary keratinocyte cultures free of dermal fibroblasts were used to investigate the effect of varying cyclic AMP (cAMP) concentrations on epidermal cell function. Addition of 10-3, 10-4 or 10-5 M dibutyryl cAMP to plated ...
Refinements in Mathematical Models to Predict Aneurysm Growth and Rupture
(Blackwell Publishing Inc, 2006-11)
The growth of aneurysms and eventually their likelihood of rupture depend on the determination of the stress and strain within the aneurysm wall and the exact reproduction of its geometry. A numerical model is developed ...