Now showing items 1-6 of 6
Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion ...
Gene gun application in the generation of effector T cells for adoptive immunotherapy
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-01)
We utilized the gene gun to transfect subcutaneous D5 melanoma and MT-901 mammary carcinoma tumors in situ with a granulocyte/macrophage-colony-stimulating factor (GM-CSF) plasmid complexed to gold particles. There was ...
CTLA-4 blockade augments human T lymphocyte-mediated suppression of lung tumor xenografts in SCID mice
(Springer-Verlag, 2005-10)
Previous studies by others using transplantable murine tumor models have demonstrated that the administration of antibodies that block CTLA-4 interaction with B7 can provoke the elimination of established tumors, and that ...
Injectable microparticle–gel system for prolonged and localized lidocaine release. II. in vivo anesthetic effects
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocols for postoperative pain are beset by either the short duration of the anesthetic effect or requirement of hospitalization of the patients. We reported herein a novel treatment by applying to the ...
Glycoprotein analysis using protein microarrays and mass spectrometry
(Wiley Subscription Services, Inc., A Wiley Company, 2010-09)
Protein glycosylation plays an important role in a multitude of biological processes such as cell–cell recognition, growth, differentiation, and cell death. It has been shown that specific glycosylation changes are key in ...
Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer
(WILEY-VCH Verlag, 2008-08)
The current study analyzed reverse phase protein arrays (RPPA) as a means to experimentally validate biomarkers in blood samples. One microliter samples of sera ( n 14= 1471), and plasma ( n 14= 1478) were serially diluted ...