Now showing items 1-10 of 88
Cytogenetic analysis of posterior uveal melanoma
(Elsevier, 1993-03)
Cytogenetic analysis was performed on short-term cultures of primary tumor samples from seven patients with posterior uveal melanoma. Informative data were obtained from four patients, all of whom had a near-diploid ...
Effects of stimulus level on nonspectral frequency discrimination by human subjects
(Elsevier, 1994-08)
Frequency difference limens were determined as a function of reference-stimulus level for pulsatile electrical stimuli in 5 postlingually deaf human subjects with Nucleus-22 cochlear implants and for sinusoidally ...
Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro
(Elsevier, 1994-06-15)
Aminoglycoside antibiotics such as gentamicin have long been known to destroy cochlear and vestibular hair cells in vivo. In the cochlea outer hair cells are preferentially affected. In contrast, gentamicin will not damage ...
Functional assessment using Constant's Shoulder Scale after modified radical and selective neck dissection
(Wiley Subscription Services, Inc., A Wiley Company, 2002-05)
Background Constant's Shoulder Scale is a validated and widely applied instrument for assessment of shoulder function. We used this instrument to assess which treatment and demographic variables contribute to shoulder ...
Human papillomavirus infection in “young” versus “old” patients with squamous cell carcinoma of the head and neck
(John Wiley & Sons, Inc., 2000-10)
Background Human papillomavirus (HPV) represents a potential risk factor for squamous cell cancer of the head and neck (SCCHN). We evaluated the prevalence of HPV DNA in patients with SCCHN diagnosed at the University of ...
Transoral trans-stomal microdebrider excision of tracheal papillomatosis
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05)
Objectives: To describe a technique for surgical removal of recurrent respiratory papilloma in the distal trachea in patients with an indwelling tracheostomy tube. Methods: A transoral trans-stomal technique for removal ...
Sympathetic paraganglioma as an unusual cause of Horner's syndrome
(John Wiley & Sons, Inc., 2001-04)
Background Paragangliomas are rare tumors arising from paraganglionic tissue of neural crest origin. They are present in any location where autonomic ganglia are found. The most common location in the head and neck is the ...
A PCR-RFLP Assay for the A716T Mutation in the WFS1 Gene, a Common Cause of Low-Frequency Sensorineural Hearing Loss
(Mary Ann Liebert, Inc., publishers, 2002-09-01)
Nonsyndromic low-frequency sensorineural hearing loss (LFSNHL) is an unusual type of hearing loss that affects frequencies at 2,000 Hz and below. Recently, we reported five different heterozygous missense mutations in the ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...
High-dose cisplatin in advanced head and neck cancer
(Springer-Verlag, 1987-04)
In 22 patients with advanced squamous cell carcinoma of the head and neck we evaluated the efficacy and toxicity of 200 mg/m 2 cisplatin administered in 3% NaCl with vigorous hydration. Six patients had previously untreated ...