Now showing items 1-4 of 4
Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers
(Springer-Verlag, 2006-04)
Preclinical investigations have established that methamphetamine (MA) produces long-term changes in dopamine (DA) neurons in the striatum. Human studies have suggested similar effects and correlated motor and cognitive ...
Nicotine may relieve symptoms of Parkinson's disease
(Springer-Verlag, 1994-09)
Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated ...
Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders
(Springer-Verlag, 2001-10)
Rationale: There exists a wide range of animal models and measures designed to assess anxiety or fearfulness. However, the relationship between these models and clinical anxiety symptoms and syndromes is unclear. The ...
A statistical approach for classifying change in cognitive function in individuals following pharmacologic challenge: an example with alprazolam
(Springer-Verlag, 2006-05)
The effects of any drug treatment on cognitive function are typically studied in groups of subjects. Observations made about the behavior of the drug, in the study sample, are then generalized to the population from which ...