Now showing items 1-4 of 4
A densitometer for quantitative autoradiography
(Elsevier, 1983-11)
A low cost spot densitometer system is described. This system is useful for quantitative autoradiography of local cerebral glucose utilization, blood flow, receptor binding and other applications requiring densitometry on ...
Autoradiographic quantification of muscarinic cholinergic synaptic markers in bat, shrew, and rat brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
We employed radioligand binding autoradiography to determine the distributions of pre- and postsynaptic cholinergic radioligand binding sites in the brains of two species of bat, one species of shrew, and the rat. High ...
Localization of muscarinic M3 receptor protein and M3 receptor binding in rat brain
(Elsevier, 1994-11)
A family of receptor subtypes, defined either by molecular (ml-m5) or pharmacological (M1-M4) analysis, mediates muscarinic cholinergic neurotransmission in brain. The distribution and functions of the m3 receptor protein ...
Quantitative in vivo receptor binding IV: Detection of muscarinic receptor down-regulation by equilibrium and by tracer kinetic methods
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1991-09)
Newly-developed methods for estimation of in vivo binding to neurotransmitter receptors should enable the detection and quantification of physiologic or pathologic changes in receptor numbers. In the present study, both ...