Now showing items 31-40 of 113
Hypocretin-1 causes G protein activation and increases ACh release in rat pons
(Blackwell Science, Ltd, 2003-10)
The effects of the arousal-promoting peptide hypocretin on brain stem G protein activation and ACh release were examined using 16 adult Sprague-Dawley rats. In vitro [ 35 S]GTPγS autoradiography was used to test the ...
Cholecystokinin Activates a Variety of Intracellular Signal Transduction Mechanisms in Rodent Pancreatic Acinar Cells
(Munksgaard International PublishersBlackwell Publishing Ltd, 2002-12)
Cholecystokinin (CCK) acting through its G protein-coupled receptor is now known to activate a variety of intracellular signaling mechanisms and thereby regulate a complex array of cellular functions in pancreatic acinar ...
Analysis of the Factors that Limit the Ability of Feeder Cells to Maintain the Undifferentiated State of Human Embryonic Stem Cells
(Mary Ann Liebert, Inc., 2009-05)
Human embryonic stem cell (hESC) culture is routinely performed using inactivated mouse embryonic fibroblasts (MEFs) as a feeder cell layer (FL). Although these cells maintain pluripotency of hESCs, the molecular basis for ...
Burkholderia cenocepacia ET12 strain activates TNFR1 signalling in cystic fibrosis airway epithelial cells
(Blackwell Publishing Ltd, 2008-01)
Burkholderia cenocepacia is an important pulmonary pathogen in individuals with cystic fibrosis (CF). Infection is often associated with severe pulmonary inflammation, and some patients develop a fatal necrotizing pneumonia ...
Insulin Signaling in Microdomains of the Plasma Membrane
(Munksgaard International PublishersBlackwell Publishing Ltd, 2003-11)
Intracellular trafficking and replication of Burkholderia cenocepacia in human cystic fibrosis airway epithelial cells
(Blackwell Publishing Ltd, 2006-09)
We investigated the trafficking of Burkholderia cenocepacia , an opportunistic respiratory pathogen of persons with cystic fibrosis (CF), in immortalized CF airway epithelial cells in vitro . Our results indicate that ...
Structural Features of Vps35p Involved in Interaction with Other Subunits of the Retromer Complex
(Blackwell Publishing Ltd, 2007-12)
Prenatal Exposure of the Ovine Fetus to Androgens Sexually Differentiates the Steroid Feedback Mechanisms That Control Gonadotropin Releasing Hormone Secretion and Disrupts Ovarian Cycles
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2002-02)
Exposure of the female sheep fetus to exogenous testosterone in early pregnancy permanently masculinizes the reproductive neuroendocrine axis. Specifically, in utero androgens given to female lambs from day 30 to 90 of a ...
Force and power output of fast and slow skeletal muscles from mdx mice 6-28 months old
(Blackwell Science Ltd, 2001-09)
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray
(WILEY-VCH Verlag, 2009-06)
Protein microarrays have been used to explore whether a humoral response to pancreatic cancer-specific tumor antigens has utility as a biomarker of pancreatic cancer. To determine if such arrays can be used to identify ...