Now showing items 1-10 of 77
CCK antagonists reveal that CCK-8 and JMV-180 interact with different sites on the rat pancreatic acinar cell CCKA receptor
(Elsevier, 1994)
The ability of CCKA antagonists to inhibit full and partial CCK agonists of the rat pancreatic acinar cell CCKA receptor has been studied. When isolated rat pancreatic acini were superfused with CCK-8 (10 pM-1 nM) or CCK-4 ...
Rat Pancreatic Nucleoside Diphosphate Kinase, a Novel Regulator of Cholecystokinin Receptor Affinity
(Blackwell Publishing Ltd, 1994-03)
Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells
(John Wiley & Sons, Inc., 1999-10)
Cholecystokinin (CCK) is a regulatory peptide that is primarily expressed in two adult cell types: endocrine cells of the intestine and neurons of the central nervous system. To determine the ontogeny of CCK expression ...
Amylin increases cyclic AMP formation in L6 myocytes through calcitonin gene-related peptide receptors
(Elsevier, 1991-06-14)
The cellular function of amylin is investigated in L6 myocytes, a rat skeletal muscle cell line. Both rat amylin and human amylin-amide acutely cause a dose-dependent increase in cyclic AMP formation in L6 myocytes. 100 ...
Neurophysiological, pharmacological and behavioral evidence for medial thalamic mediation of cocaine-induced dopaminergic analgesia
(Elsevier, 1992-02-14)
These studies examined the effects of cocaine on thalamic neurons that respond maximally either to noxious or to innocuous somatic stimulation. Cocaine attenuated high intensity electrically-evoked nociceptive responses ...
Follicle-stimulating hormone signal transduction: Role of carbohydrate in aromatase induction in immature rat Sertoli cells
(Elsevier, 1991-08)
Receptor activated adenylate cyclase acts as a major transmembrane signalling system. It is widely accepted that upon binding to its receptor, follicle-stimulating hormone (FSH) activates the cAMP-dependent pathway which ...
Short-term potentiation of off-responses in turtle horizontal cells
(Elsevier, 1991-04-12)
Depolarizing responses to light off were studied in turtle horizontal cells using intracellular recording in the everted eyecup preparation. In many cells the off-response showed two components (fast and slow) which could ...
Intracellular calcium and hormone release from nerve endings of the neurohypophysis in the presence of opioid agonists and antagonists
(Springer-Verlag, 1992-09)
Rat neural lobes and isolated nerve terminals from the neurohypophysis were stimulated in the presence of different opioid agonists and antagonists. The secretion of arginine vasopressin and oxytocin and rise in cytoplasmic ...
Effects of calyculin A on amylase release in streptolysin-O permeabilized acinar cells
(Elsevier, 1992-12-30)
The effects of the phosphatase inhibitors calyculin A and okadaic acid on amylase release from streptolysin-O permeabilized rat pancreatic acini were investigated. Both agents induced similar biphasic effects with moderate ...
Interactions of intracellular mediators of amylase secretion in permeabilized pancreatic acini
(Elsevier, 1991-01-23)
Mouse pancreatic acini were permeabilized with streptolysin O to investigate amylase secretion stimulated by various intracellular mediators and the kinetics of secretion as a function of temperature. Amylase secretion was ...