Now showing items 1-5 of 5
Glycogen synthase kinase-3 regulates mouse oocyte homologue segregation
(Wiley Subscription Services, Inc., A Wiley Company, 2003-01)
Intracellular regulation of oocyte meiosis is not completely understood. However, reversible phosphorylation, which involves serine/threonine protein kinases and phosphatases (PP), is an important mediator. Glycogen synthase ...
Glycogen synthase kinase-3 regulation of chromatin segregation and cytokinesis in mouse preimplantation embryos
(Wiley Subscription Services, Inc., A Wiley Company, 2007-02)
Glycogen synthase kinase-3 (GSK-3) is a highly conserved serine/threonine protein kinase implicated in diverse cellular processes. Activity of GSK-3 is essential for meiotic chromatin segregation in oocytes, yet expression ...
Distribution of co-activators CBP and p300 during mouse oocyte and embryo development
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structurally related transcriptional co-activators that activate expression of many eukaryotic genes. Current dogma would suggest that ...
Tibialis anterior muscles in mdx mice are highly susceptible to contraction-induced injury
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-07)
Skeletal muscles of patients with Duchenne muscular dystrophy (DMD) and mdx mice lack dystrophin and are more susceptible to contraction-induced injury than control muscles. Our purpose was to develop an assay based on the ...
Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown
(Wiley Subscription Services, Inc., A Wiley Company, 2003-05)
Okadaic acid (OA)-induced germinal vesicle breakdown (GVBD) and localization of protein phosphatase-1 (PP1) in oocyte nuclei are suggestive of PP1's role in regulating oocyte GVBD. To explore this possibility, we microinjected ...