Now showing items 1-10 of 39
Effect of p53 overexpression on radiation sensitivity of human colon cancer cells
(John Wiley & Sons, Inc., 1997)
Substantial controversy surrounds our understanding of the effect of p53 status on radiation sensitivity. To assess directly the role of p53 expression on radiation sensitivity, we chose a conditional expression system ...
Imaging Changes after Stereotactic Radiosurgery of Primary and Secondary Malignant Brain Tumors
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-01)
After radiosurgery of malignant tumors, it can be difficult to discriminate between transient treatment effects, radiation necrosis, and tumor progression on post-treatment imaging. Misinterpretation of an enlarging lesion ...
Modeling intra-tumor protein expression heterogeneity in tissue microarray experiments
(John Wiley & Sons, Ltd., 2008-05-20)
Tissue microarrays (TMAs) measure tumor-specific protein expression via high-density immunohistochemical staining assays. They provide a proteomic platform for validating cancer biomarkers emerging from large-scale DNA ...
Induction of glutathione S -transferase-Π in Barrett's metaplasia and Barrett's adenocarcinoma cell lines
(John Wiley & Sons, Inc., 1999-02)
Barrett's metaplasia consists of columnar epithelium that replaces the normal esophageal mucosa in patients with chronic gastroesophageal reflux. Because intestinal-type Barrett's metaplasia is the major risk factor for ...
Dosimetric comparison of bolus and continuous injections of CC49 monoclonal antibody in a colon cancer xenograft model Presented at the Sixth Conference on Radioimmunodetection and Radioimmunotherapy of Cancer, Princeton, New Jersey, October 10-12, 1996.
(John Wiley & Sons, Inc., 1997-12-15)
BACKGROUND Improved understanding of dose and effective dose calculations may contribute to the optimization of fractionated radioimmunotherapy. METHODS Comparison three-dimensional tumor dosimetry was performed on ...
Analysis on binary responses with ordered covariates and missing data
(John Wiley & Sons, Ltd., 2007-08-15)
We consider the situation of two ordered categorical variables and a binary outcome variable, where one or both of the categorical variables may have missing values. The goal is to estimate the probability of response of ...
An academic health center cost analysis of screening mammography
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
BACKGROUND The current study sought to determine the institutional financial impact of a screening mammography (SM) program in the context of an integrated cancer center. METHODS Using administrative databases, 10,048 ...
Estimation for paired binomial data with application to radiation therapy
(John Wiley & Sons, Ltd., 2001-11-30)
We compare and contrast several different methods for estimating the effect of treatment when responses are paired binomial observations. The ratio of binomial probabilities is the parameter of interest, while the binomial ...
Concurrent cisplatin, paclitaxel, and radiotherapy as preoperative treatment for patients with locoregional esophageal carcinoma
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-15)
BACKGROUND A Phase II trial was conducted at the University of Michigan to determine the efficacy of a preoperative regimen of concurrent cisplatin, paclitaxel, and radiation for patients with locoregional esophageal ...