Now showing items 1-10 of 67
The influence of beam model differences in the comparison of dose calculation algorithms for lung cancer treatment planning
(IOP Publishing Ltd, 2005-03-07)
In this study, we show that beam model differences play an important role in the comparison of dose calculated with various algorithms for lung cancer treatment planning. These differences may impact the accurate correlation ...
Modeling intra-tumor protein expression heterogeneity in tissue microarray experiments
(John Wiley & Sons, Ltd., 2008-05-20)
Tissue microarrays (TMAs) measure tumor-specific protein expression via high-density immunohistochemical staining assays. They provide a proteomic platform for validating cancer biomarkers emerging from large-scale DNA ...
Costlets: A Generalized Approach to Cost Functions for Automated Optimization of IMRT Treatment Plans
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-12)
We present the creation and use of a generalized cost function methodology based on costlets for automated optimization for conformal and intensity modulated radiotherapy treatment plans. In our approach, cost functions ...
Semiparametric Modeling of Longitudinal Measurements and Time-to-Event Data–A Two-Stage Regression Calibration Approach
(Blackwell Publishing Inc, 2008-12)
In this article we investigate regression calibration methods to jointly model longitudinal and survival data using a semiparametric longitudinal model and a proportional hazards model. In the longitudinal model, a biomarker ...
Prevention of visual stress and migraine with precision spectral filters
(Wiley Subscription Services, Inc., A Wiley Company, 2007-11)
Individuals who suffer migraine, particularly migraine with visual aura (MwA), are susceptible to physiologically strong visual stimuli and find them aversive. Strong stimuli including bright light and certain visual ...
Analysis on binary responses with ordered covariates and missing data
(John Wiley & Sons, Ltd., 2007-08-15)
We consider the situation of two ordered categorical variables and a binary outcome variable, where one or both of the categorical variables may have missing values. The goal is to estimate the probability of response of ...
Mechanism and pharmacological specificity of dUTPase-mediated protection from DNA damage and cytotoxicity in human tumor cells
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
Purpose : We have reported previously that the expression of E. coli dUTPase (dutE) can protect HT29 cells from 5-fluorodeoxyuridine (FdUrd)-induced DNA fragmentation and cytotoxicity. In the study reported here, we further ...
Highly Efficient, Near-Infrared Electrophosphorescence from a Pt–Metalloporphyrin Complex The authors acknowledge financial support from the U.S. Dept. of the Army, CECOM for the phase 14II SBIR program (contract no. 14W15P7T-06-C-T201), and Universal Display Corporation.
(WILEY-VCH Verlag, 2007-02-05)
No Abstract
Estimation for paired binomial data with application to radiation therapy
(John Wiley & Sons, Ltd., 2001-11-30)
We compare and contrast several different methods for estimating the effect of treatment when responses are paired binomial observations. The ratio of binomial probabilities is the parameter of interest, while the binomial ...
Doubly Penalized Buckley–James Method for Survival Data with High-Dimensional Covariates
(Blackwell Publishing Inc, 2008-03)
Recent interest in cancer research focuses on predicting patients' survival by investigating gene expression profiles based on microarray analysis. We propose a doubly penalized Buckley–James method for the semiparametric ...