Now showing items 141-150 of 174
In vivo real-time imaging of TGF-Β-induced transcriptional activation of the RANK ligand gene promoter in intraosseous prostate cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2004-06-01)
BACKGROUND Current animal models of prostate cancer (CaP) bone metastasis do not allow measurement of either tumor growth in bone over time or activation of gene promoters in intraosseous tumors. To develop these methods, ...
Smoking and acute urinary retention: The Olmsted County study of urinary symptoms and health status among men
(Wiley Subscription Services, Inc., A Wiley Company, 2009-05-15)
BACKGROUND Previous reports have suggested an inverse relationship between smoking and surgery for benign prostatic hyperplasia (BPH). We hypothesized that acute urinary retention (AUR), an adverse outcome of this disease ...
FYN is overexpressed in human prostate cancer
(Blackwell Publishing Ltd, 2009-01)
To test the hypothesis that FYN , a member of the SRC family of kinases (SFKs), is up-regulated in prostate cancer, as FYN is functionally distinct from other SFKs, and interacts with FAK and paxillin (PXN), regulators of ...
Phenotypic characterization of immortalized normal and primary tumor-derived human prostate epithelial cell cultures
(John Wiley & Sons, Inc., 2000-07-01)
BACKGROUND Cell lines can provide powerful model systems for the study of human tumorigenesis. However, the human prostate cancer cell lines studied most intensively by investigators (PC3, DU145, and LNCaP) were established ...
Caveats for modeling disease free survival after radical prostatectomy See reply to counterpoint and referenced original article on pages 234–5 and 404–11, this issue.
(John Wiley & Sons, Inc., 2000-07-15)
No abstract.
Use of the National Cancer Data Base to develop clinical trials accrual targets that are appropriate for minority ethnicity patients
(Wiley Subscription Services, Inc., A Wiley Company, 2006-01-01)
BACKGROUND Disparities in cancer outcome among different subsets of the American population related to ethnic background have been well documented. Clinical trials represent the most powerful strategy for improving cancer ...
Immunogenetic Therapy of Human Melanoma Utilizing Autologous Tumor Cells Transduced to Secrete Granulocyte-Macrophage Colony-Stimulating Factor
(Mary Ann Liebert, Inc., publishers, 2000-04-10)
We performed a clinical study of five patients with melanoma to evaluate the immunobiological effects of retrovirally transduced autologous tumor cells given as a vaccine to prime draining lymph nodes. Patients were ...
Editorial comment: Urethral injections for female stress incontinence
(Blackwell Publishing Ltd, 2006-09)
Annexin II/Annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer
(Wiley Subscription Services, Inc., A Wiley Company, 2008-10-01)
One of the most life-threatening complications of prostate cancer is skeletal metastasis. In order to develop treatment for metastasis, it is important to understand its molecular mechanisms. Our work in this field has ...
Treatment of androgen-independent prostate cancer using antimicrotubule agents docetaxel and estramustine in combination: an experimental study
(John Wiley & Sons, Inc., 2000-09-01)
BACKGROUND Estramustine in combination with other chemotherapeutic agents has demonstrated synergy in hormone-refractory prostate cancer. Docetaxel has demonstrated antineoplastic activity in a variety of chemotherapeut ...