Now showing items 1-10 of 16
The intraperitoneal delivery of radiolabeled monoclonal antibodies: studies on the regional delivery advantage
(Springer-Verlag, 1988-06)
The i.p. delivery of murine monoclonal antibody was compared with i.v. delivery in normal mice and rats, in normal nude mice and in those with i.p. human ovarian carcinoma xenografts. In normal rats, all classes of antibodies ...
Monoclonal antibody (5G6.4) against ovarian carcinoma shows inhibition of in vitro colony formation
(Elsevier, 1987-07)
Monoclonal antibodies (MAbs) have the potential for diagnosis and therapy of cancer. 5G6.4 is a MAb of the IgG2a class which was produced by immunization of BALB/c mice with human ovarian carcinoma (Ov Ca) cells. To further ...
Effect of alpha-adrenergic blockade and anticholinergic agents on the decentralized primate bladder
(Wiley Subscription Services, Inc., A Wiley Company, 1985)
The effect of anticholinergic and alpha-adrenergic blocking agents on the primate bladder decentralized at the sacral level was studied. Both agents diminish the intravesical pressure response to filling and slightly ...
A semi-automated fluorescent (SAF) assay using viable, whole cells for screening hybridoma supernatants
(Elsevier, 1987-06-16)
In the production of monoclonal antibodies, a rapid, sensitive, accurate assay is needed for the critical step of screening. We report the modification of an assay using viable whole cells for screening hybridoma supernatants. ...
Stress inconthence and detrusor instability/urge incontinence
(Wiley Subscription Services, Inc., A Wiley Company, 1985)
The overall incidence of detrusor instability in 603 women with stress incontinence was 30%. One hundred seventy-two women had detrusor instability and/or urge incontinence preoperatively. Twenty-three additional women ...
Rodent carcinogenesis bioassay with oxisuran, a selective immunosuppressive agent
(Elsevier, 1983-09)
The carcinogenic potential of oxisuran, a synthetic immunosuppressive agent, was studied for 80 weeks and 104 weeks in mice and rats, respectively. Groups of 50 mice and 70 rats of each sex received oxisuran at doses of ...
Detrusor response to outlet obstruction
(Springer-Verlag, 1984-11)
Bladder responses to outlet obstruction are thought to involve muscular hyperplasia, increased pressure, and finally, decompensation. While these things probably do occur, the process of bladder response to obstruction ...
Evaluation of chronic toxicity and carcinogenesis in rodents with the synthetic analgesic, tilidine fumarate
(Elsevier, 1986-05)
The carcinogenic potential of tilidine fumarate, a synthetic analgesic, was studied for 80 and 104 weeks in mice and rats, respectively. Groups of 50 albino CF1 mice and 65 albino Wistar rats of each sex received tilidine ...