Prognostic analysis for carcinoid tumors of the rectum: a single institutional analysis of 106 cases

Abstract

Rectal carcinoids is a rare rectal tumor with a good prognosis. The aim of this study was to assess its clinicopathological characteristics and prognostic factors in a single institution.Clinical and pathological information was retrospectively collected in a single institution and patients’ outcomes were determined. Multivariate analyses were performed to find independent prognostic factors attributed to overall survival.106 patients with rectal carcinoid were included. (66%) underwent trananal local excision and (34%) had transabdominal surgery. The 5 year survival rate wass 87%. Muscularis invasion was the only independent prognostic factor for predicting 5 year survival (p=0.00046). Tumor size was found significantly to be associated with muscular invasion (p=0.00003). The area under the curve (AUC) of tumor size in the (ROC) curve for predicting muscular invasion was 0.92.Patients with rectal carcinoid have a good prognosis. Muscular invasion is an independent risk factor of survival.