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Congenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009)

dc.contributor.authorNorth, C.en_US
dc.contributor.authorKruger, J. M.en_US
dc.contributor.authorVenta, Patrick J.en_US
dc.contributor.authorMiller, J. M.en_US
dc.contributor.authorRosenstein, D. S.en_US
dc.contributor.authorRandall, E. K.en_US
dc.contributor.authorWhite, B.en_US
dc.contributor.authorFitzgerald, S. D.en_US
dc.date.accessioned2011-01-31T17:24:47Z
dc.date.available2011-11-01T15:13:01Zen_US
dc.date.issued2010-09en_US
dc.identifier.citationNorth, C.; Kruger, J.M.; Venta, P.J.; Miller, J.M.; Rosenstein, D.S.; Randall, E.K.; White, B.; Fitzgerald, S.D.; (2010). "Congenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009)." Journal of Veterinary Internal Medicine 24(5): 1055-1062. <http://hdl.handle.net/2027.42/79070>en_US
dc.identifier.issn0891-6640en_US
dc.identifier.issn1939-1676en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/79070
dc.description.abstractEctopic ureters (EUs) associated with varying combinations of urinary incontinence, hydronephrosis, and urinary tract infection have been identified in related North American Entlebucher Mountain Dogs.To characterize the disease phenotype in affected dogs and evaluate possible modes of inheritance.Twenty client-owned Entlebucher Mountain Dogs. Nine dogs had clinical signs of urinary tract disease.Prospective case series in which 17 dogs were evaluated with excretory urography, ultrasonography, and urethrocystoscopy. Three additional dogs were evaluated by necropsy alone. Clinical and pedigree histories from 165 North American Entlebuchers were compiled for analysis.Eleven female and 2 male dogs were found to have EUs. Six females and 1 male were continent. Bilateral intravesicular ectopic ureters (IVEUs) were identified in 9 dogs, bilateral extravesicular ectopic ureters (EVEUs) in 3 dogs, and 1 dog had IVEU and EVEU. Hydronephrosis was identified in 5 dogs, 3 of which had bilateral IVEUs. Two necropsied dogs had bilateral hydronephrosis with presumed ureterovesical junction obstruction associated with chronic granulation tissue or lymphoplasmacytic inflammation. Twenty-six dogs with EUs were identified in the pedigree. Because of incomplete penetrance, mode of inheritance could not be determined.Ureteral ectopia is common in North American Entlebucher Mountain Dogs and clinical signs alone could not reliably predict disease phenotype. EVEUs were associated with urinary incontinence and occasionally hydronephrosis. IVEUs were clinically silent or associated with hydronephrosis. Further analyses are necessary to confirm and characterize the hereditary nature of the disorder.en_US
dc.format.extent1471077 bytes
dc.format.extent3106 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Incen_US
dc.subject.otherHydronephrosisen_US
dc.subject.otherInterureteral Orifice Distanceen_US
dc.subject.otherUreteral Obstructionen_US
dc.subject.otherUrinary Tract Infectionen_US
dc.titleCongenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009)en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MIen_US
dc.contributor.affiliationotherDepartment of Small Animal Clinical Sciences, East Lansing, MIen_US
dc.contributor.affiliationotherDepartment of Pathobiology and Diagnostic Investigation, East Lansing, MIen_US
dc.contributor.affiliationotherDepartment of Michigan State University College of Veterinary Medicine, East Lansing, MIen_US
dc.contributor.affiliationotherFlorida Veterinary Referral Center, Estero, FL.en_US
dc.contributor.affiliationotherVCA South Shore Animal Hospital, Weymouth, MAen_US
dc.contributor.affiliationotherColorado State University Veterinary Teaching Hospital, Fort Collins, COen_US
dc.identifier.pmid20666980en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/79070/1/j.1939-1676.2010.0562.x.pdf
dc.identifier.doi10.1111/j.1939-1676.2010.0562.xen_US
dc.identifier.sourceJournal of Veterinary Internal Medicineen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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