Congenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009)
dc.contributor.author | North, C. | en_US |
dc.contributor.author | Kruger, J. M. | en_US |
dc.contributor.author | Venta, Patrick J. | en_US |
dc.contributor.author | Miller, J. M. | en_US |
dc.contributor.author | Rosenstein, D. S. | en_US |
dc.contributor.author | Randall, E. K. | en_US |
dc.contributor.author | White, B. | en_US |
dc.contributor.author | Fitzgerald, S. D. | en_US |
dc.date.accessioned | 2011-01-31T17:24:47Z | |
dc.date.available | 2011-11-01T15:13:01Z | en_US |
dc.date.issued | 2010-09 | en_US |
dc.identifier.citation | North, C.; Kruger, J.M.; Venta, P.J.; Miller, J.M.; Rosenstein, D.S.; Randall, E.K.; White, B.; Fitzgerald, S.D.; (2010). "Congenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009)." Journal of Veterinary Internal Medicine 24(5): 1055-1062. <http://hdl.handle.net/2027.42/79070> | en_US |
dc.identifier.issn | 0891-6640 | en_US |
dc.identifier.issn | 1939-1676 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/79070 | |
dc.description.abstract | Ectopic ureters (EUs) associated with varying combinations of urinary incontinence, hydronephrosis, and urinary tract infection have been identified in related North American Entlebucher Mountain Dogs.To characterize the disease phenotype in affected dogs and evaluate possible modes of inheritance.Twenty client-owned Entlebucher Mountain Dogs. Nine dogs had clinical signs of urinary tract disease.Prospective case series in which 17 dogs were evaluated with excretory urography, ultrasonography, and urethrocystoscopy. Three additional dogs were evaluated by necropsy alone. Clinical and pedigree histories from 165 North American Entlebuchers were compiled for analysis.Eleven female and 2 male dogs were found to have EUs. Six females and 1 male were continent. Bilateral intravesicular ectopic ureters (IVEUs) were identified in 9 dogs, bilateral extravesicular ectopic ureters (EVEUs) in 3 dogs, and 1 dog had IVEU and EVEU. Hydronephrosis was identified in 5 dogs, 3 of which had bilateral IVEUs. Two necropsied dogs had bilateral hydronephrosis with presumed ureterovesical junction obstruction associated with chronic granulation tissue or lymphoplasmacytic inflammation. Twenty-six dogs with EUs were identified in the pedigree. Because of incomplete penetrance, mode of inheritance could not be determined.Ureteral ectopia is common in North American Entlebucher Mountain Dogs and clinical signs alone could not reliably predict disease phenotype. EVEUs were associated with urinary incontinence and occasionally hydronephrosis. IVEUs were clinically silent or associated with hydronephrosis. Further analyses are necessary to confirm and characterize the hereditary nature of the disorder. | en_US |
dc.format.extent | 1471077 bytes | |
dc.format.extent | 3106 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Inc | en_US |
dc.subject.other | Hydronephrosis | en_US |
dc.subject.other | Interureteral Orifice Distance | en_US |
dc.subject.other | Ureteral Obstruction | en_US |
dc.subject.other | Urinary Tract Infection | en_US |
dc.title | Congenital Ureteral Ectopia in Continent and Incontinent-Related Entlebucher Mountain Dogs: 13 Cases (2006–2009) | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI | en_US |
dc.contributor.affiliationother | Department of Small Animal Clinical Sciences, East Lansing, MI | en_US |
dc.contributor.affiliationother | Department of Pathobiology and Diagnostic Investigation, East Lansing, MI | en_US |
dc.contributor.affiliationother | Department of Michigan State University College of Veterinary Medicine, East Lansing, MI | en_US |
dc.contributor.affiliationother | Florida Veterinary Referral Center, Estero, FL. | en_US |
dc.contributor.affiliationother | VCA South Shore Animal Hospital, Weymouth, MA | en_US |
dc.contributor.affiliationother | Colorado State University Veterinary Teaching Hospital, Fort Collins, CO | en_US |
dc.identifier.pmid | 20666980 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/79070/1/j.1939-1676.2010.0562.x.pdf | |
dc.identifier.doi | 10.1111/j.1939-1676.2010.0562.x | en_US |
dc.identifier.source | Journal of Veterinary Internal Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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