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Assessment of transition readiness skills and adherence in pediatric liver transplant recipients

dc.contributor.authorFredericks, Emily M.en_US
dc.contributor.authorDore-Stites, Dawnen_US
dc.contributor.authorWell, Andrewen_US
dc.contributor.authorMagee, John C.en_US
dc.contributor.authorFreed, Gary L.en_US
dc.contributor.authorShieck, Victoria L.en_US
dc.contributor.authorJames Lopez, M.en_US
dc.date.accessioned2011-01-31T17:37:01Z
dc.date.available2012-02-21T18:47:01Zen_US
dc.date.issued2010-12en_US
dc.identifier.citationFredericks, Emily M.; Dore-Stites, Dawn; Well, Andrew; Magee, John C.; Freed, Gary L.; Shieck, Victoria; James Lopez, M.; (2010). "Assessment of transition readiness skills and adherence in pediatric liver transplant recipients." Pediatric Transplantation 14(8): 944-953. <http://hdl.handle.net/2027.42/79176>en_US
dc.identifier.issn1397-3142en_US
dc.identifier.issn1399-3046en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/79176
dc.description.abstractFredericks EM, Dore-Stites D, Well A, Magee JC, Freed GL, Shieck V, Lopez MJ. Assessment of transition readiness skills and adherence in pediatric liver transplant recipients. Pediatr Transplantation 2010: 14:944–953. © 2010 John Wiley & Sons A/S.To examine transition readiness, adherence, and health outcomes in pediatric liver transplant recipients using a clinically administered screening measure. Seventy-one pediatric liver transplant recipients (11–20 yr) and 58 parents completed a clinic-based TRS measuring perceived and demonstrated self-management skills, AoR for health-related tasks, regimen knowledge, and psychosocial adjustment. Adherence was measured using s.d. of immunosuppressants, proportion of immunosuppressant blood levels out of target range, and clinic attendance. Health outcomes included liver test panels, biopsies, rejection episodes, and hospitalizations. Results indicate that all domains of transition readiness, with the exception of demonstrated skills, and non-adherence were positively correlated with age. Proportion of immunosuppressant blood levels below target range was positively correlated with self-management skills and increased responsibility for medication tasks. Parent regimen knowledge was associated with clinic attendance. Health outcomes were significantly related to medication non-adherence, but not to transition readiness domains. Medication adherence is considered to be a key factor in the transition from pediatric to adult-centered transplant care. Non-adherence is associated with an increased risk for medical complications and is potentially modifiable. Interventions to promote self-management skills and adherence should be an essential component of transition planning.en_US
dc.format.extent145338 bytes
dc.format.extent3106 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.subject.otherTransitionen_US
dc.subject.otherAdolescenceen_US
dc.subject.otherAdherenceen_US
dc.subject.otherPediatric Liver Transplantationen_US
dc.subject.otherSelf-managementen_US
dc.titleAssessment of transition readiness skills and adherence in pediatric liver transplant recipientsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPediatricsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pediatrics, University of Michigan Health System, Ann Arbor, MIen_US
dc.contributor.affiliationumDepartment of Surgery, University of Michigan Health System, Ann Arbor, MI, USAen_US
dc.identifier.pmid20598086en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/79176/1/j.1399-3046.2010.01349.x.pdf
dc.identifier.doi10.1111/j.1399-3046.2010.01349.xen_US
dc.identifier.sourcePediatric Transplantationen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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