A Retrospective Review of the Sleep Characteristics in Patients with Chronic Fatigue Syndrome and Fibromyalgia
dc.contributor.author | Spitzer, A. Robert | en_US |
dc.contributor.author | Broadman, Melissa | en_US |
dc.date.accessioned | 2011-01-31T17:38:58Z | |
dc.date.available | 2011-09-06T16:03:06Z | en_US |
dc.date.issued | 2010-07 | en_US |
dc.identifier.citation | Spitzer, A. Robert; Broadman, Melissa; (2010). "A Retrospective Review of the Sleep Characteristics in Patients with Chronic Fatigue Syndrome and Fibromyalgia." Pain Practice 10(4): 294-300. <http://hdl.handle.net/2027.42/79193> | en_US |
dc.identifier.issn | 1530-7085 | en_US |
dc.identifier.issn | 1533-2500 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/79193 | |
dc.description.abstract | This study characterizes findings on sleep testing and Human Leukocyte Antigen (HLA) markers in a group of patients with fibromyalgia (FM) and chronic fatigue syndrome (CFS). One hundred eighteen patients seen in a general neurology practice over 5 years meeting standard clinical criteria for FM or CFS were analyzed retrospectively. Cases of untreated sleep apnea or restless legs syndrome were excluded prior to inclusion in this study. Ninety-two patients had multiple sleep latency testing (MSLT). Seventy-three (80%) were abnormal by standard criteria. Of 57 females having positive MSLTs, 22 (39%) had one or more periods of sleep onset rapid eye movement (SOREM), and 5 of 16 (31%) males with positive MSLTs had one or more SOREM. Highly fragmented sleep, as previously described in FM, was seen but not analyzed quantitatively. HLA DQB1*0602 was obtained in 74 patients, and positive in 32 (43%), P < 0.0001 compared with published values in 228 populations. In our patients, who presented with neuromuscular fatigue or generalized pain, we found a sleep disorder characterized by objective hypersomnia. Some patients had characteristics of narcolepsy. Objective assessment by sleep studies can assist the diagnostic process, aid future research, and provide rationale for treatment. | en_US |
dc.format.extent | 76919 bytes | |
dc.format.extent | 3106 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Inc | en_US |
dc.subject.other | Fibromyalgia | en_US |
dc.subject.other | Chronic Fatigue Syndrome | en_US |
dc.subject.other | Sleep Disorder | en_US |
dc.subject.other | Narcolepsy | en_US |
dc.subject.other | HLA Marker | en_US |
dc.subject.other | Hypersomnia | en_US |
dc.title | A Retrospective Review of the Sleep Characteristics in Patients with Chronic Fatigue Syndrome and Fibromyalgia | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationother | Wayne State University School of Medicine, Detroit, Michigan; | en_US |
dc.identifier.pmid | 20230458 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/79193/1/j.1533-2500.2009.00352.x.pdf | |
dc.identifier.doi | 10.1111/j.1533-2500.2009.00352.x | en_US |
dc.identifier.source | Pain Practice | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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