Mapping and Ablation of Frequent Post-Infarction Premature Ventricular Complexes
dc.contributor.author | Sarrazin, Jean-Francois | en_US |
dc.contributor.author | Good, Eric D. | en_US |
dc.contributor.author | Kuhne, Michael | en_US |
dc.contributor.author | Oral, Hakan | en_US |
dc.contributor.author | Pelosi, Frank Jr. | en_US |
dc.contributor.author | Chugh, Aman | en_US |
dc.contributor.author | Jongnarangsin, Krit | en_US |
dc.contributor.author | Crawford, Thomas | en_US |
dc.contributor.author | Ebinger, Matthew | en_US |
dc.contributor.author | Morady, Fred | en_US |
dc.contributor.author | Bogun, Frank M. | en_US |
dc.date.accessioned | 2011-01-31T17:47:14Z | |
dc.date.available | 2011-11-01T15:13:00Z | en_US |
dc.date.issued | 2010-09 | en_US |
dc.identifier.citation | Sarrazin, Jean-Francois; Good, Eric; Kuhne, Michael; Oral, Hakan; Pelosi, Frank; Chugh, Aman; Jongnarangsin, Krit; Crawford, Thomas; Ebinger, Matthew; Morady, Fred; Bogun, Frank; (2010). "Mapping and Ablation of Frequent Post-Infarction Premature Ventricular Complexes." Journal of Cardiovascular Electrophysiology 21(9): 1002-1008. <http://hdl.handle.net/2027.42/79266> | en_US |
dc.identifier.issn | 1045-3873 | en_US |
dc.identifier.issn | 1540-8167 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/79266 | |
dc.description.abstract | Mapping of Post-Infarction PVCs . Introduction: Premature ventricular complexes (PVCs) occur frequently in patients with heart disease. The sites of origin of PVCs in patients with prior myocardial infarction and the response to catheter ablation have not been systematically assessed. Methods and Results: In 28 consecutive patients (24 men, age 60 ± 10, ejection fraction [EF] 0.37 ± 0.14) with remote myocardial infarction referred for catheter ablation of symptomatic refractory PVCs, the PVCs were mapped by activation mapping or pace mapping using an irrigated-tip catheter in conjunction with an electroanatomic mapping system. The site of origin (SOO) was classified as being within low-voltage (scar) tissue (amplitude ≤1.5 mV) or tissue with preserved voltage (>1.5 mV). The SOO was confined to endocardial scar tissue in 24/28 patients (86%). The SOO was outside of scar in 3 patients and could not be identified in 1 patient. At the SOO, local endocardial activation preceded the PVC by 46 ± 19 ms, and the electrogram amplitude during sinus rhythm was 0.48 ± 0.34 mV. The PVCs were effectively ablated in 25/28 patients (89%), resulting in a decrease in PVC burden on a 24-hour Holter monitor from 15.6 ± 12.3% to 2.4 ± 4.2% (P < 0.001). The SOO most often was confined to scar tissue located in the left ventricular septum and the papillary muscles. Conclusion: Similar to post-infarction ventricular tachycardia, PVCs after remote myocardial infarction most often originate within scar tissue. Catheter ablation of these PVCs has a high-success rate. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1002-1008, September 2010) | en_US |
dc.format.extent | 495518 bytes | |
dc.format.extent | 3106 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Inc | en_US |
dc.subject.other | Catheter Ablation | en_US |
dc.subject.other | Myocardial Infarction | en_US |
dc.subject.other | Premature Ventricular Complexes | en_US |
dc.subject.other | Electroanatomic Mapping | en_US |
dc.subject.other | Antiarrhythmic Drugs | en_US |
dc.title | Mapping and Ablation of Frequent Post-Infarction Premature Ventricular Complexes | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbsecondlevel | Physiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Cardiology, University of Michigan Cardiovascular Center, Ann Arbor, Michigan, USA | en_US |
dc.identifier.pmid | 20455976 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/79266/1/j.1540-8167.2010.01771.x.pdf | |
dc.identifier.doi | 10.1111/j.1540-8167.2010.01771.x | en_US |
dc.identifier.source | Journal of Cardiovascular Electrophysiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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