Minimax Emission Computed Tomography using High-Resolution Anatomical Side Information and B-Spline Models
dc.contributor.author | Hero, Alfred O. | en_US |
dc.contributor.author | Piramuthu, Robinson | en_US |
dc.contributor.author | Fessler, Jeffrey A. | en_US |
dc.contributor.author | Titus, Steven R. | en_US |
dc.date.accessioned | 2011-08-18T18:20:48Z | |
dc.date.available | 2011-08-18T18:20:48Z | |
dc.date.issued | 1999-04 | en_US |
dc.identifier.citation | Hero, A.O.; Piramuthu, R.; Fessler, J.A.; Titus, S.R. (1999). "Minimax Emission Computed Tomography using High-Resolution Anatomical Side Information and B-Spline Models." IEEE Transactions on Information Theory 45(3): 920-938. <http://hdl.handle.net/2027.42/85822> | en_US |
dc.identifier.issn | 0018-9448 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/85822 | |
dc.description.abstract | In this paper a minimax methodology is presented for combining information from two imaging modalities having different intrinsic spatial resolutions. The focus application is emission computed tomography (ECT), a low-resolution modality for reconstruction of radionuclide tracer density, when supplemented by high-resolution anatomical boundary information extracted from a magnetic resonance image (MRI) of the same imaging volume. The MRI boundary within the two-dimensional (2-D) slice of interest is parameterized by a closed planar curve. The Cramer-Rao (CR) lower bound is used to analyze estimation errors for different boundary shapes. Under a spatially inhomogeneous Gibbs field model for the tracer density a representation for the minimax MRI-enhanced tracer density estimator is obtained. It is shown that the estimator is asymptotically equivalent to a penalized maximum likelihood (PML) estimator with resolution-selective Gibbs penalty. Quantitative comparisons are presented using the iterative space alternating generalized expectation maximization (SAGE-FM) algorithm to implement the PML estimator with and without minimax weight averaging. | en_US |
dc.publisher | IEEE | en_US |
dc.title | Minimax Emission Computed Tomography using High-Resolution Anatomical Side Information and B-Spline Models | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Biomedical Engineering | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Electrical Engineering and Computer Science. | en_US |
dc.contributor.affiliationother | Lattice Semiconductor, Hillsboro, OR 97124 USA. | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/85822/1/Fessler86.pdf | |
dc.identifier.doi | 10.1109/18.761333 | en_US |
dc.identifier.source | IEEE Transactions on Information Theory | en_US |
dc.owningcollname | Electrical Engineering and Computer Science, Department of (EECS) |
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