Microfluidic model of bubble lodging in microvessel bifurcations
dc.contributor.author | Calderón, Andrés J. | en_US |
dc.contributor.author | Heo, Yun Seok | en_US |
dc.contributor.author | Huh, Dongeun | en_US |
dc.contributor.author | Futai, Nobuyuki | en_US |
dc.contributor.author | Takayama, Shuichi | en_US |
dc.contributor.author | Fowlkes, J. Brian | en_US |
dc.contributor.author | Bull, Joseph L. | en_US |
dc.date.accessioned | 2011-11-15T16:08:59Z | |
dc.date.available | 2011-11-15T16:08:59Z | |
dc.date.issued | 2006-12-11 | en_US |
dc.identifier.citation | Calderón, Andrés J.; Heo, Yun Seok; Huh, Dongeun; Futai, Nobuyuki; Takayama, Shuichi; Fowlkes, J. Brian; Bull, Joseph L. (2006). "Microfluidic model of bubble lodging in microvessel bifurcations." Applied Physics Letters 89(24): 244103-244103-3. <http://hdl.handle.net/2027.42/87802> | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/87802 | |
dc.description.abstract | The lodging mechanisms and dynamics of cardiovascular gas bubbles are investigated in microfluidic model bifurcations made of poly(dimethylsiloxane). This work is motivated by gas embolotherapy for the potential treatment of cancer by tumor infarction. The results show that the critical driving pressure below which a bubble will lodge in a bifurcation is significantly less than the driving pressure required to dislodge it. From the results the authors estimate that gas bubbles from embolotherapy can lodge in vessels 20 μm20μm or smaller in diameter, and conclude that bubbles may potentially be used to reduce blood flow to tumor microcirculation. | en_US |
dc.publisher | The American Institute of Physics | en_US |
dc.rights | © The American Institute of Physics | en_US |
dc.title | Microfluidic model of bubble lodging in microvessel bifurcations | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Physics | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/87802/2/244103_1.pdf | |
dc.identifier.doi | 10.1063/1.2402898 | en_US |
dc.identifier.source | Applied Physics Letters | en_US |
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dc.owningcollname | Physics, Department of |
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