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Microengineered synthetic cellular microenvironment for stem cells
dc.contributor.authorSun, Yubingen_US
dc.contributor.authorWeng, Shinuoen_US
dc.contributor.authorFu, Jianpingen_US
dc.date.accessioned2012-07-12T17:23:46Z
dc.date.available2013-09-03T15:38:27Zen_US
dc.date.issued2012-07en_US
dc.identifier.citationSun, Yubing; Weng, Shinuo; Fu, Jianping (2012). "Microengineered synthetic cellular microenvironment for stem cells." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 4(4): 414-427. <http://hdl.handle.net/2027.42/92053>en_US
dc.identifier.issn1939-5116en_US
dc.identifier.issn1939-0041en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/92053
dc.description.abstractStem cells possess the ability of self‐renewal and differentiation into specific cell types. Therefore, stem cells have great potentials in fundamental biology studies and clinical applications. The most urgent desire for stem cell research is to generate appropriate artificial stem cell culture system, which can mimic the dynamic complexity and precise regulation of the in vivo biochemical and biomechanical signals, to regulate and direct stem cell behaviors. Precise control and regulation of the biochemical and biomechanical stimuli to stem cells have been successfully achieved using emerging micro/nanoengineering techniques. This review provides insights into how these micro/nanoengineering approaches, particularly microcontact printing and elastomeric micropost array, are applied to create dynamic and complex environment for stem cells culture. WIREs Nanomed Nanobiotechnol 2012, 4:414–427. doi: 10.1002/wnan.1175 For further resources related to this article, please visit the WIREs website .en_US
dc.publisherJohn Wiley & Sons, Inc.en_US
dc.titleMicroengineered synthetic cellular microenvironment for stem cellsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiomedical Engineeringen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USAen_US
dc.contributor.affiliationumDepartment of Mechanical Engineering, Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, MI, USAen_US
dc.identifier.pmid22639443en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/92053/1/1175_ftp.pdf
dc.identifier.doi10.1002/wnan.1175en_US
dc.identifier.sourceWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnologyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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