A survey study of index food‐related allergic reactions and anaphylaxis management
dc.contributor.author | Jacobs, Tammy S. | en_US |
dc.contributor.author | Greenhawt, Matthew J. | en_US |
dc.contributor.author | Hauswirth, David | en_US |
dc.contributor.author | Mitchell, Lynda | en_US |
dc.contributor.author | Green, Todd D. | en_US |
dc.date.accessioned | 2012-09-05T14:46:00Z | |
dc.date.available | 2013-10-18T17:47:29Z | en_US |
dc.date.issued | 2012-09 | en_US |
dc.identifier.citation | Jacobs, Tammy S.; Greenhawt, Matthew J.; Hauswirth, David; Mitchell, Lynda; Green, Todd D. (2012). "A survey study of index food‐related allergic reactions and anaphylaxis management." Pediatric Allergy and Immunology 23(6). <http://hdl.handle.net/2027.42/93515> | en_US |
dc.identifier.issn | 0905-6157 | en_US |
dc.identifier.issn | 1399-3038 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/93515 | |
dc.description.abstract | Background: Initial food‐allergic reactions are often poorly recognized and under‐treated. Methods: Parents of food‐allergic children were invited to complete an online questionnaire, designed with Kids with Food Allergies Foundation , about their children’s first food‐allergic reactions resulting in urgent medical evaluation. Results: Among 1361 reactions, 76% (95% CI 74–79%) were highly likely to represent anaphylaxis based on NIAID/FAAN criteria. Only 34% (95% CI 31–37%) of these were administered epinephrine. In 56% of these, epinephrine was administered by emergency departments; 20% by parents; 9% by paramedics; 8% by primary care physicians; and 6% by urgent care centers. In 26% of these, epinephrine was given within 15 min of the onset of symptoms; 54% within 30 min; 82% within 1 h; and 93% within 2 h. Factors associated with a decreased likelihood of receiving epinephrine for anaphylaxis included age <12 months, milk and egg triggers, and symptoms of abdominal pain and/or diarrhea. Epinephrine was more likely to be given to asthmatic children and children with peanut or tree nut ingestion prior to event. Post‐treatment, 42% of reactions likely to represent anaphylaxis were referred to allergists, 34% prescribed and/or given epinephrine auto‐injectors, 17% trained to use epinephrine auto‐injectors, and 19% given emergency action plans. Of patients treated with epinephrine, only half (47%) were prescribed epinephrine auto‐injectors. Conclusions: Only one‐third of initial food‐allergic reactions with symptoms of anaphylaxis were recognized and treated with epinephrine. Fewer than half of patients were referred to allergists. There is still a need to increase education and awareness about food‐induced anaphylaxis. | en_US |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.subject.other | Food Hypersensitivity | en_US |
dc.subject.other | Emergency Treatment | en_US |
dc.subject.other | Epinephrine | en_US |
dc.subject.other | Anaphylaxis | en_US |
dc.title | A survey study of index food‐related allergic reactions and anaphylaxis management | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pediatrics | en_US |
dc.subject.hlbsecondlevel | Allergy and Clinical Immunology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Allergy & Immunology, University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Division of Pulmonary Medicine, Allergy & Immunology, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA | en_US |
dc.contributor.affiliationother | Kids with Food Allergies Foundation, Doylestown, PA, USA | en_US |
dc.contributor.affiliationother | Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, The Ohio State University and Nationwide Children's Hospital, Columbus, OH, USA | en_US |
dc.contributor.affiliationother | Department of Pediatrics, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/93515/1/pai1315.pdf | |
dc.identifier.doi | 10.1111/j.1399-3038.2012.01315.x | en_US |
dc.identifier.source | Pediatric Allergy and Immunology | en_US |
dc.identifier.citedreference | Lee JM, Greenes DS. Biphasic anaphylactic reactions in pediatrics. Pediatrics 2000: 106: 762 – 6. | en_US |
dc.identifier.citedreference | Gupta R, Sheikh A, Strachan DP, Anderson HR. Time trends in allergic disorders in the UK. Thorax 2007: 62: 91 – 6. | en_US |
dc.identifier.citedreference | Gupta R, Sheikh A, Strachan D, Anderson HR. Increasing hospital admissions for systemic allergic disorders in England: analysis of national admissions data. BMJ 2003: 327: 1142 – 3. | en_US |
dc.identifier.citedreference | Poulos LM, Waters AM, Correll PK, Loblay RH, Marks GB. Trends in hospitalizations for anaphylaxis, angioedema, and urticaria in Australia, 1993–1994 to 2004–2005. J Allergy Clin Immunol 2007: 120: 878 – 84. | en_US |
dc.identifier.citedreference | Rudders SA, Banerji A, Vassallo MF, Clark S, Camargo CA Jr. Trends in pediatric emergency department visits for food‐induced anaphylaxis. J Allergy Clin Immunol 2010: 126: 385 – 8. | en_US |
dc.identifier.citedreference | Decker WW, Campbell RL, Manivannan V, et al. The etiology and incidence of anaphylaxis in Rochester, Minnesota: a report from the Rochester Epidemiology Project. J Allergy Clin Immunol 2008: 122: 1161 – 5. | en_US |
dc.identifier.citedreference | Lieberman P, Camargo CA Jr, Bohlke K, et al. Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. Ann Allergy Asthma Immunol 2006: 97: 596 – 602. | en_US |
dc.identifier.citedreference | Lin RY, Anderson AS, Shah SN, Nurruzzaman F. Increasing anaphylaxis hospitalizations in the first 2 decades of life: New York State, 1990–2006. Ann Allergy Asthma Immunol 2008: 101: 387 – 93. | en_US |
dc.identifier.citedreference | Clark S, Bock SA, Gaeta TJ, Brenner BE, Cydulka RK, Camargo CA. Multicenter study of emergency department visits for food allergies. J Allergy Clin Immunol 2004: 113: 347 – 52. | en_US |
dc.identifier.citedreference | Clark S, Camargo CA Jr. Emergency management of food allergy: systems perspective. Curr Opin Allergy Clin Immunol 2005: 5: 293 – 8. | en_US |
dc.identifier.citedreference | Russell S, Monroe K, Losek JD. Anaphylaxis management in the pediatric emergency department: opportunities for improvement. Pediatr Emerg Care 2010: 26: 71 – 6. | en_US |
dc.identifier.citedreference | Moneret‐Vautrin DA, Morisset M, Flabbee J, Beaudouin E, Kanny G. Epidemiology of life‐threatening and lethal anaphylaxis: a review. Allergy 2005: 60: 443 – 51. | en_US |
dc.identifier.citedreference | Sampson HA, Mendelson L, Rosen JP. Fatal and near‐fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 1992: 327: 380 – 4. | en_US |
dc.identifier.citedreference | Brown SG. Clinical features and severity grading of anaphylaxis. J Allergy Clin Immunol 2004: 114: 371 – 6. | en_US |
dc.identifier.citedreference | Mullins RJ. Anaphylaxis: risk factors for recurrence. Clin Exp Allergy 2003: 33: 1033 – 40. | en_US |
dc.identifier.citedreference | Simons FE. Anaphylaxis in infants: can recognition and management be improved? J Allergy Clin Immunol 2007: 120: 537 – 40. | en_US |
dc.identifier.citedreference | Novembre E, Cianferoni A, Bernardini R, et al. Anaphylaxis in children: clinical and allergologic features. Pediatrics 1998: 101: E8. | en_US |
dc.identifier.citedreference | Lane RD, Bolte RG. Pediatric anaphylaxis. Pediatr Emerg Care 2007: 23: 49 – 56; quiz 57–60. | en_US |
dc.identifier.citedreference | Pumphrey RS. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy 2000: 30: 1144 – 50. | en_US |
dc.identifier.citedreference | Bock SA, Munoz‐Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 2001: 107: 191 – 3. | en_US |
dc.identifier.citedreference | Bock SA, Munoz‐Furlong A, Sampson HA. Further fatalities caused by anaphylactic reactions to food, 2001–2006. J Allergy Clin Immunol 2007: 119: 1016 – 8. | en_US |
dc.identifier.citedreference | Pumphrey R. Anaphylaxis: can we tell who is at risk of a fatal reaction? Curr Opin Allergy Clin Immunol 2004: 4: 285 – 90. | en_US |
dc.identifier.citedreference | Pumphrey RS, Gowland MH. Further fatal allergic reactions to food in the United Kingdom, 1999–2006. J Allergy Clin Immunol 2007: 119: 1018 – 9. | en_US |
dc.identifier.citedreference | Greenberger PA, Rotskoff BD, Lifschultz B. Fatal anaphylaxis: postmortem findings and associated comorbid diseases. Ann Allergy Asthma Immunol 2007: 98: 252 – 7. | en_US |
dc.identifier.citedreference | Anchor J, Settipane RA. Appropriate use of epinephrine in anaphylaxis. Am J Emerg Med 2004: 22: 488 – 90. | en_US |
dc.identifier.citedreference | Beno SM, Nadel FM, Alessandrini EA. A survey of emergency department management of acute urticaria in children. Pediatr Emerg Care 2007: 23: 862 – 8. | en_US |
dc.identifier.citedreference | Webb LM, Lieberman P. Anaphylaxis: a review of 601 cases. Ann Allergy Asthma Immunol 2006: 97: 39 – 43. | en_US |
dc.identifier.citedreference | Braganza SC, Acworth JP, McKinnon DR, Peake JE, Brown AF. Paediatric emergency department anaphylaxis: different patterns from adults. Arch Dis Child 2006: 91: 159 – 63. | en_US |
dc.identifier.citedreference | Lieberman P. Biphasic anaphylactic reactions. Ann Allergy Asthma Immunol 2005: 95: 217 – 26; quiz 226, 258. | en_US |
dc.identifier.citedreference | Sampson HA, Munoz‐Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report – Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol 2006: 117: 391 – 7. | en_US |
dc.identifier.citedreference | Sicherer SH, Sampson HA. 9. Food allergy. J Allergy Clin Immunol 2006: 117 ( 2 Suppl. Mini‐Primer ): S470 – 5. | en_US |
dc.identifier.citedreference | Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics 2011: 128: e9 – 17. | en_US |
dc.identifier.citedreference | Lieberman P, Nicklas RA, Oppenheimer J, et al. The diagnosis and management of anaphylaxis practice parameter: 2010 update. J Allergy Clin Immunol 2010: 126: 477 – 80, e1 – 42. | en_US |
dc.identifier.citedreference | Kemp SF, Lockey RF. Anaphylaxis: a review of causes and mechanisms. J Allergy Clin Immunol 2002: 110: 341 – 8. | en_US |
dc.identifier.citedreference | Sampson HA, Munoz‐Furlong A, Bock SA, et al. Symposium on the definition and management of anaphylaxis: summary report. J Allergy Clin Immunol 2005: 115: 584 – 91. | en_US |
dc.identifier.citedreference | Simons FE. Anaphylaxis, killer allergy: long‐term management in the community. J Allergy Clin Immunol 2006: 117: 367 – 77. | en_US |
dc.identifier.citedreference | Simons FE, Frew AJ, Ansotegui IJ, et al. Risk assessment in anaphylaxis: current and future approaches. J Allergy Clin Immunol 2007: 120 ( 1 Suppl. ): S2 – 24. | en_US |
dc.identifier.citedreference | Brown AF, McKinnon D, Chu K. Emergency department anaphylaxis: a review of 142 patients in a single year. J Allergy Clin Immunol 2001: 108: 861 – 6. | en_US |
dc.identifier.citedreference | Sampson HA. Anaphylaxis and emergency treatment. Pediatrics 2003: 111 ( 6 Pt 3 ): 1601 – 8. | en_US |
dc.identifier.citedreference | Smit DV, Cameron PA, Rainer TH. Anaphylaxis presentations to an emergency department in Hong Kong: incidence and predictors of biphasic reactions. J Emerg Med 2005: 28: 381 – 8. | en_US |
dc.identifier.citedreference | Wang J, Sampson HA. Food anaphylaxis. Clin Exp Allergy 2007: 37: 651 – 60. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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