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Polytopic vector analysis of soil, dust, and serum samples to evaluate exposure sources of PCDD/Fs
dc.contributor.authorTowey, Timothy P.en_US
dc.contributor.authorBarabás, Noémien_US
dc.contributor.authorDemond, Averyen_US
dc.contributor.authorFranzblau, Alfreden_US
dc.contributor.authorGarabrant, David H.en_US
dc.contributor.authorGillespie, Brenda W.en_US
dc.contributor.authorLepkowski, Jamesen_US
dc.contributor.authorAdriaens, Peteren_US
dc.date.accessioned2012-10-02T17:19:57Z
dc.date.available2013-11-04T19:53:16Zen_US
dc.date.issued2012-10en_US
dc.identifier.citationTowey, Timothy P.; Barabás, Noémi ; Demond, Avery; Franzblau, Alfred; Garabrant, David H.; Gillespie, Brenda W.; Lepkowski, James; Adriaens, Peter (2012). "Polytopic vector analysis of soil, dust, and serum samples to evaluate exposure sources of PCDD/Fs." Environmental Toxicology and Chemistry 31(10): 2191-2200. <http://hdl.handle.net/2027.42/93658>en_US
dc.identifier.issn0730-7268en_US
dc.identifier.issn1552-8618en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/93658
dc.description.abstractAs part of the University of Michigan Dioxin Exposure Study, soil, household dust, and serum samples were collected from more than 750 households in five populations around the city of Midland and in Jackson and Calhoun Counties, Michigan, USA. Polytopic vector analysis, a type of receptor model, was applied to better understand the potential sources of polychlorinated dibenzo‐ p ‐dioxins and polychlorinated dibenzofurans found in these samples and to quantify the contributions of the sources in each matrix across populations. The results indicated that source signatures found in soil are similar to those found in dust, reflecting various combustion profiles, pentachlorophenol, and graphite electrode sludge. The profiles associated with contamination in the Tittabawassee River, likely related to historical discharges from the Dow Chemical Company facility in Midland, exhibited the largest differences among the regional populations sampled. Differences in serum source contributions among the study populations were consistent with some of the regional differences observed in soil samples. However, the age trends of these differences suggested that they are related to past exposures, rather than ongoing sources. Environ. Toxicol. Chem. 2012; 31: 2191–2200. © 2012 SETACen_US
dc.publisherJohn Wiley & Sons, Inc.en_US
dc.subject.otherMultivariate Statisticsen_US
dc.subject.otherDioxinsen_US
dc.subject.otherOrganochlorinesen_US
dc.subject.otherEnvironmental Chemistryen_US
dc.titlePolytopic vector analysis of soil, dust, and serum samples to evaluate exposure sources of PCDD/Fsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumDepartment of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumInstitute for Social Research, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationotherLimnoTech, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationotherLimnoTech, Ann Arbor, Michigan, USA.en_US
dc.identifier.pmid22806962en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/93658/1/1942_ftp.pdf
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/93658/2/etc_1942_sm_SupplFig1.pdf
dc.identifier.doi10.1002/etc.1942en_US
dc.identifier.sourceEnvironmental Toxicology and Chemistryen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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