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Synthesis of bridgehead nitrogen heterocycles
dc.contributor.authorScovill, John P.en_US
dc.contributor.authorBurckhalter, Joseph H.en_US
dc.date.accessioned2013-02-12T19:00:58Z
dc.date.available2013-02-12T19:00:58Z
dc.date.issued1980-01en_US
dc.identifier.citationScovill, John P.; Burckhalter, Joseph H. (1980). "Synthesis of bridgehead nitrogen heterocycles." Journal of Heterocyclic Chemistry 17(1): 23-27. <http://hdl.handle.net/2027.42/96346>en_US
dc.identifier.issn0022-152Xen_US
dc.identifier.issn1943-5193en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/96346
dc.description.abstractReductive cyclizations of N ‐[2‐(2‐pyridyl)ethyl]imides were accomplished by employing a palladium on carbon catalyst in ethanolic acetic acid as the hydrogenation medium. Reduction of the corresponding N ‐[2‐(2‐quinolyl)ethyl]imides ceased at the 1,2,3,4‐tetrahydroquinolyl stage. Controlled reduction of the tetrahydroquinolyl imides with sodium borohydride gave amido alcohols which afforded bridgehead nitrogen heterocycles upon cyclodehydration.en_US
dc.publisherWiley‐Blackwellen_US
dc.titleSynthesis of bridgehead nitrogen heterocyclesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelOrganic Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumInterdepartmental Program in Medicinal Chemistry, The University of Michigan, Ann Arbor, Michigan 48104en_US
dc.contributor.affiliationotherDivision of Experimental Therapeutics, Walter Reed Army Institute of Research Washington, DC 20012en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/96346/1/5570170105_ftp.pdf
dc.identifier.doi10.1002/jhet.5570170105en_US
dc.identifier.sourceJournal of Heterocyclic Chemistryen_US
dc.identifier.citedreferenceR. J. Thill,Ph.D. Thesis, The University of Michigan, Ann Arbor, MI( 1971 ).en_US
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dc.identifier.citedreferenceG. A. Edwards, W. H. Perkin, Jr. and F. W. Stoyle, J. Chem. Soc., 195 ( 1925 ).en_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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