Retention of Stem Cell Plasticity in Avian Primitive Streak Cells and the Effects of Local Microenvironment
dc.contributor.author | Wang, Xiao‐yu | en_US |
dc.contributor.author | Li, Yan | en_US |
dc.contributor.author | Ma, Zheng‐lai | en_US |
dc.contributor.author | Wang, Li‐jing | en_US |
dc.contributor.author | Chuai, Manli | en_US |
dc.contributor.author | Münsterberg, Andrea | en_US |
dc.contributor.author | Geng, Jian‐guo | en_US |
dc.contributor.author | Yang, Xuesong | en_US |
dc.date.accessioned | 2013-03-05T18:17:57Z | |
dc.date.available | 2014-05-01T14:28:12Z | en_US |
dc.date.issued | 2013-03 | en_US |
dc.identifier.citation | Wang, Xiao‐yu ; Li, Yan; Ma, Zheng‐lai ; Wang, Li‐jing ; Chuai, Manli; Münsterberg, Andrea ; Geng, Jian‐guo ; Yang, Xuesong (2013). "Retention of Stem Cell Plasticity in Avian Primitive Streak Cells and the Effects of Local Microenvironment." The Anatomical Record 296(3): 533-543. <http://hdl.handle.net/2027.42/96743> | en_US |
dc.identifier.issn | 1932-8486 | en_US |
dc.identifier.issn | 1932-8494 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/96743 | |
dc.description.abstract | Primitive streak ( PS ) is the first structure occurring in embryonic gastrulation, in which the epiblast cells undergo the epithelial‐mesenchymal transition to become the loose mesoderm cells subsequently. Because the mesoderm cells departing from different portions of PS are blessed with disparate migration trajectory and differentiation fate, one question is when the cell fate is determinated. To understand whether the cell fate and cell migration pattern will be alternated along with the microenvironment transformation, the traditional transplantation technology was used to replace the anterior PS cells in HH 4 host embryo using posterior PS tissue labeled by green fluorescent protein ( GFP ) in the same stage donor embryo, and then, we tracked the migration trajectory of the GFP ‐positive cells with fluorescence stereomicroscope after incubation, and eventually verified the cell contribution from the transplants with in situ hybridization and immunocytochemistry. The same experimental strategy applied for posterior PS site replacement in host embryo. We found that the transplanted posterior PS cells to anterior part of streak followed the anterior PS cell migration pattern rather than kept its posterior streak cell migration trajectory, and so did vice versa. In addition, the transplants were involved in the contribution to the subsequent organogenesis as the local PS tissues affirmed by specific expression of myocardial or hematopoietic markers. Therefore, our data strongly suggest that the PS cells still keep stem cell plasticity during gastrulation and the eventual cell fate will depend on the spatial gene expression within local microenvironment along with development. Anat Rec, 296:533–543, 2012. © 2012 Wiley Periodicals, Inc. | en_US |
dc.publisher | Wiley Periodicals, Inc. | en_US |
dc.subject.other | Gastrulation | en_US |
dc.subject.other | Local Microenvironment | en_US |
dc.subject.other | Primitive Streak | en_US |
dc.subject.other | Graft | en_US |
dc.subject.other | Cell Migration | en_US |
dc.title | Retention of Stem Cell Plasticity in Avian Primitive Streak Cells and the Effects of Local Microenvironment | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.identifier.pmid | 23382139 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/96743/1/ar22640.pdf | |
dc.identifier.doi | 10.1002/ar.22640 | en_US |
dc.identifier.source | The Anatomical Record | en_US |
dc.identifier.citedreference | Risau W, Flamme I. 1995. Vasculogenesis. Annu Rev Cell Dev Biol 11: 73 – 91. | en_US |
dc.identifier.citedreference | Chapman SC, Collignon J, Schoenwolf GC, Lumsden A. 2001. Improved method for chick whole‐embryo culture using a filter paper carrier. Dev Dyn 220: 284 – 289. | en_US |
dc.identifier.citedreference | Chapman SC, Matsumoto K, Cai Q, Schoenwolf GC. 2007. Specification of germ layer identity in the chick gastrula. BMC Dev Biol 7: 91 – 106. | en_US |
dc.identifier.citedreference | Chuai M, Weijer CJ. 2008. The mechanisms underlying primitive streak formation in the chick embryo. Curr Top Dev Biol 81: 135 – 156. | en_US |
dc.identifier.citedreference | Chuai M, Zeng W, Yang X, Boychenko V, Glazier JA, Weijer CJ. 2006. Cell movement during chick primitive streak formation. Dev Biol 296: 137 – 149. | en_US |
dc.identifier.citedreference | Cui C, Yang X, Chuai M, Glazier JA, Weijer CJ. 2005. Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Dev Biol 284: 37 – 47. | en_US |
dc.identifier.citedreference | Downs KM. 2009. The enigmatic primitive streak: prevailing notions and challenges concerning the body axis of mammals. Bioessays 31: 892 – 902. | en_US |
dc.identifier.citedreference | Hamburger V, Hamilton HL. 1951. A series of normal stages in the development of the chick embryo. J Morphol 88: 44 – 92. | en_US |
dc.identifier.citedreference | Henrique D, Adam J, Myat A, Chitnis A, Lewis J, Ish‐Horowicz D. 1995. Expression of a Delta homologue in prospective neurons in the chick. Nature 375: 787 – 790. | en_US |
dc.identifier.citedreference | James RG, Schultheiss TM. 2003. Patterning of the avian intermediate mesoderm by lateral plate and axial tissues. Dev Biol 253: 109 – 124. | en_US |
dc.identifier.citedreference | Kimura W, Yasugi S, Stern CD, Fukuda K. 2006. Fate and plasticity of the endoderm in the early chick embryo. Dev Biol 289: 283 – 295. | en_US |
dc.identifier.citedreference | Kinder SJ, Tsang TE, Quinlan GA, Hadjantonakis AK, Nagy A, Tam PP. 1999. The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo. Development 126: 4691 – 4701. | en_US |
dc.identifier.citedreference | Knezevic V, De Santo R, Mackem S. 1998. Continuing organizer function during chick tail development. Development 125: 1791 – 1801. | en_US |
dc.identifier.citedreference | Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. 2004. Expression of VE‐cadherin in zebrafish embryos: a new tool to evaluate vascular development. Dev Dyn 231: 204 – 213. | en_US |
dc.identifier.citedreference | Lawson A, Schoenwolf GC. 2003. Epiblast and primitive‐streak origins of the endoderm in the gastrulating chick embryo. Development 130: 3491 – 3501. | en_US |
dc.identifier.citedreference | Lopez‐Sanchez C, Garcia‐Masa N, Ganan CM, Garcia‐Martinez V. 2009. Movement and commitment of primitive streak precardiac cells during cardiogenesis. Int J Dev Biol 53: 1445 – 1455. | en_US |
dc.identifier.citedreference | Mikawa T, Poh AM, Kelly KA, Ishii Y, Reese DE. 2004. Induction and patterning of the primitive streak, an organizing center of gastrulation in the amniote. Dev Dyn 229: 422 – 432. | en_US |
dc.identifier.citedreference | Olivera‐Martinez I, Coltey M, Dhouailly D, Pourquie O. 2000. Mediolateral somitic origin of ribs and dermis determined by quail‐chick chimeras. Development 127: 4611 – 4617. | en_US |
dc.identifier.citedreference | Rosenquist GC. 1972. Endoderm movements in the chick embryo between the early short streak and head process stages. J Exp Zool 180: 95 – 103. | en_US |
dc.identifier.citedreference | Selleck MA, Stern CD. 1991. Fate mapping and cell lineage analysis of Hensen's node in the chick embryo. Development 112: 615 – 626. | en_US |
dc.identifier.citedreference | Somi S, Klein AT, Houweling AC, Ruijter JM, Buffing AA, Moorman AF, van den Hoff MJ. 2006. Atrial and ventricular myosin heavy‐chain expression in the developing chicken heart: strengths and limitations of non‐radioactive in situ hybridization. J Histochem Cytochem 54: 649 – 664. | en_US |
dc.identifier.citedreference | Tam PP, Behringer RR. 1997. Mouse gastrulation: the formation of a mammalian body plan. Mech Dev 68: 3 – 25. | en_US |
dc.identifier.citedreference | Yang X, Chrisman H, Weijer CJ. 2008. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N‐cadherin expression. Development 135: 3521 – 3530. | en_US |
dc.identifier.citedreference | Yang X, Dormann D, Munsterberg AE, Weijer CJ. 2002. Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. Dev Cell 3: 425 – 437. | en_US |
dc.identifier.citedreference | Yasuo H, Lemaire P. 2001. Generation of the germ layers along the animal‐vegetal axis in Xenopus laevis. Int J Dev Biol 45: 229 – 235. | en_US |
dc.identifier.citedreference | Yue Q, Wagstaff L, Yang X, Weijer C, Munsterberg A. 2008. Wnt3a‐mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development 135: 1029 – 1037. | en_US |
dc.identifier.citedreference | Zamir EA, Rongish BJ, Little CD. 2008. The ECM moves during primitive streak formation—computation of ECM versus cellular motion. PLoS Biol 6: 2163 – 2171. | en_US |
dc.identifier.citedreference | Bader D, Masaki T, Fischman DA. 1982. Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J Cell Biol 95: 763 – 770. | en_US |
dc.identifier.citedreference | Beddington RS. 1994. Induction of a second neural axis by the mouse node. Development 120: 613 – 620. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.