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Surgical margins in head and neck cancer: A contemporary review

dc.contributor.authorEisele, MD,, Daviden_US
dc.date.accessioned2013-09-04T17:18:34Z
dc.date.available2014-10-06T19:17:42Zen_US
dc.date.issued2013-09en_US
dc.identifier.citationEisele, MD,, David (2013). "Surgical margins in head and neck cancer: A contemporary review ." Head & Neck 35(9): 1362-1370. <http://hdl.handle.net/2027.42/99648>en_US
dc.identifier.issn1043-3074en_US
dc.identifier.issn1097-0347en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/99648
dc.description.abstractAdequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relating to the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as “molecular margins” and contact microscopic endoscopy, However, the limitations of these approaches need to be understood. The goal of this review was to evaluate these issues to define a more rational, standardized approach for achieving resection margin adequacy for patients with HNSCC undergoing curative resection. © 2012 Wiley Periodicals, Inc. Head Neck, 2013en_US
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherMolecular Factorsen_US
dc.subject.otherSurgical Marginsen_US
dc.subject.otherFrozen Sectionen_US
dc.subject.otherHead Neck Canceren_US
dc.subject.otherPattern of Invasionen_US
dc.titleSurgical margins in head and neck cancer: A contemporary reviewen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelOtolaryngologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Otolaryngology‐Head and Neck Surgery, University of Michigan, Ann Arbor, MIen_US
dc.contributor.affiliationotherDepartment of Otolaryngology–Head and Neck Surgery, Institut Gustave Roussy, Villejuif, Franceen_US
dc.contributor.affiliationotherDepartment Otorhinolaryngology‐Head and Neck Surgery, Centro de Tratamento e Pesquisa Hospital do Cancer A.C. Camargo, São Paulo, Brazilen_US
dc.contributor.affiliationotherENT Clinic, University of Udine, Piazzale S. Maria della Misericordia, I‐33100 Udine, Italyen_US
dc.contributor.affiliationotherDepartment of Otolaryngology‐Head and Neck Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlandsen_US
dc.contributor.affiliationotherDepartments of Surgery and Otolaryngology‐Head and Neck Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NYen_US
dc.contributor.affiliationotherDepartments of Pathology and Otolaryngology‐Head and Neck Surgery, The Johns Hopkins Medical Institutions, Baltimore, MDen_US
dc.contributor.affiliationotherDepartment of Pathology and Laboratory Medicine, University of Pittsburgh, Pittsburgh, PAen_US
dc.contributor.affiliationotherDepartment of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spainen_US
dc.contributor.affiliationotherInstituto Universitario de Oncología del Principado de Asturias, Oviedo, Spainen_US
dc.contributor.affiliationotherDivision of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australiaen_US
dc.contributor.affiliationotherDepartment of Pathology, University of Arkansas for Medical Sciences, Little Rock, ARen_US
dc.contributor.affiliationotherDepartment of Radiation Oncology, Institute of Oncology, Ljubljana, Sloveniaen_US
dc.contributor.affiliationotherDepartment of Pathology, Allegiance Health, Jackson, MIen_US
dc.contributor.affiliationotherDepartment of Pathology, Brown University School of Medicine, Rhode Island Hospital, Providence, RIen_US
dc.contributor.affiliationotherLaboratoire de Phonétique et de Phonologie, Sorbonne Nouvelle, Paris, Franceen_US
dc.contributor.affiliationotherDepartment of Otolaryngology‐Head and Neck Surgery, Mayo Clinic, Phoenix, AZen_US
dc.contributor.affiliationotherENT Clinic, University of Udine, Udine, Italyen_US
dc.contributor.affiliationotherSurgical Pathology Section, Division Anatomic Pathology, University of Alabama at Birmingham, Birmingham, ALen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/99648/1/23110_ftp.pdf
dc.identifier.doi10.1002/hed.23110en_US
dc.identifier.sourceHead & Necken_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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