111In-8-hydroxyquinoline platelet labeling in dogs
dc.contributor.author | Porter-Fink, Vicki L. | en_US |
dc.contributor.author | Eckhauser, Frederic E. | en_US |
dc.date.accessioned | 2006-04-07T18:04:09Z | |
dc.date.available | 2006-04-07T18:04:09Z | |
dc.date.issued | 1981-07 | en_US |
dc.identifier.citation | Porter-Fink, V. L., Eckhauser, Frederic E. (1981/07)."111In-8-hydroxyquinoline platelet labeling in dogs." Journal of Surgical Research 31(1): 87-92. <http://hdl.handle.net/2027.42/24318> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WM6-4BNF4HK-2TG/2/e0fa1bdbc40eb0eecfb139fc9614e893 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/24318 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6789007&dopt=citation | en_US |
dc.description.abstract | This report validates a technique of separating and labeling canine platelets using indium-111-labeled 8-hydroxyquinoline (111In-8-HQ). Platelet survival time in six normal dogs was 6.3 +/- 0.7 (SD) days. Labeling efficiency using this technique was 51.8 +/- 9.2% (SEM) and elution loss of 111In-8-HQ label from platelets was consistently less than 4%. 111In label offers no observable advantages over the more traditional 51Cr label for platelet survival studies. However, the high efficiency labeling and -[gamma]-emission characteristics of 111In-8-HQ make it more suitable for non-invasive clot localization in patients with early pulmonary emboli and peripheral venous thrombi. | en_US |
dc.format.extent | 475108 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | 111In-8-hydroxyquinoline platelet labeling in dogs | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | University of Michigan Department of Surgery, Ann Arbor, Michigan 48109, USA; Veterans Administration Hospital, Department of Surgery, Ann Arbor, Michigan 48109, USA | en_US |
dc.identifier.pmid | 6789007 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/24318/1/0000585.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-4804(81)90034-2 | en_US |
dc.identifier.source | Journal of Surgical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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