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Human PCK1 Encoding Phosphoenolpyruvate Carboxykinase Is Located on Chromosome 20q13.2

dc.contributor.authorYu, Huaen_US
dc.contributor.authorThun, Rachelen_US
dc.contributor.authorChandrasekharappa, Settara C.en_US
dc.contributor.authorTrent, Jeffrey M.en_US
dc.contributor.authorZhang, Jien_US
dc.contributor.authorMeisler, Miriam H.en_US
dc.date.accessioned2006-04-10T15:57:24Z
dc.date.available2006-04-10T15:57:24Z
dc.date.issued1993-01en_US
dc.identifier.citationYu, Hua, Thun, Rachel, Chandrasekharappa, Settara, Trent, J. M., Zhang, Ji, Meisler, Miriam H. (1993/01)."Human PCK1 Encoding Phosphoenolpyruvate Carboxykinase Is Located on Chromosome 20q13.2." Genomics 15(1): 219-221. <http://hdl.handle.net/2027.42/31063>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WG1-45PMRKN-8Y/2/2737c2260927052abb5fe43b7eb7f726en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/31063
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8432541&dopt=citationen_US
dc.description.abstractCytoplasmic liver phosphoenolpyruvate carboxykinase (GTP)(PEPCK) catalyzes a rate-limiting step in gluconeogenesis. Primers derived from the rat liver PEPCK sequence were used to amplify a portion of the human liver cDNA and to screen a YAC library of human genomic DNA. The sequences of human and rat PEPCK cDNA differed at 16% of the nucleotides compared (45/291). Analysis of a human/rodent hybrid mapping panel demonstrated concordant segregation of PCK1 with chromosome 20. Fluorescence in situ hybridization with YAC DNA further localized PCK1 to subband 20q13.2.en_US
dc.format.extent170027 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleHuman PCK1 Encoding Phosphoenolpyruvate Carboxykinase Is Located on Chromosome 20q13.2en_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Human Genetics, Center for Genetic Disease and Genome Technology, and Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.identifier.pmid8432541en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/31063/1/0000740.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1006/geno.1993.1040en_US
dc.identifier.sourceGenomicsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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