Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization
dc.contributor.author | Voorhees, John J. | en_US |
dc.contributor.author | Pettersson, Ulrika | en_US |
dc.contributor.author | Åström, Anders | en_US |
dc.contributor.author | Elder, James T. | en_US |
dc.contributor.author | Trent, Jeffrey M. | en_US |
dc.date.accessioned | 2006-09-11T19:12:44Z | |
dc.date.available | 2006-09-11T19:12:44Z | |
dc.date.issued | 1992-07 | en_US |
dc.identifier.citation | Elder, J. T.; Åström, A.; Pettersson, U.; Voorhees, J. J.; Trent, J. M.; (1992). "Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization." Human Genetics 89(5): 487-490. <http://hdl.handle.net/2027.42/47631> | en_US |
dc.identifier.issn | 1432-1203 | en_US |
dc.identifier.issn | 0340-6717 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47631 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1321791&dopt=citation | en_US |
dc.description.abstract | Two highly conserved forms of cellular retinoic acid binding protein (CRABP-I and CRABP-II) have been described, and one, CRABP-II, is highly expressed in human skin. We have utilized a 10-kb fragment containing the human CRABP-II (hCRABP-II) gene (isolated from a human genomic library) to localize hCRABP-II to human chromosome 1 band q21 by fluorescence in situ hybridization. Localization to 1q was confirmed by hybridization of a hCRABP-II cDNA clone against a human-mouse hybrid cell line containing a t(1;6)(q21;q13) translocation chromosome. The hCRABP-II gene is therefore localized to a band known to contain several other genes that are expressed in the context of epidermal differentiation, including profilaggrin, loricrin, involucrin, and calcyclin. | en_US |
dc.format.extent | 494290 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Human Genetics | en_US |
dc.subject.other | Internal Medicine | en_US |
dc.subject.other | Metabolic Diseases | en_US |
dc.subject.other | Molecular Medicine | en_US |
dc.title | Assignment of the human CRABP-II gene to chromosome 1q21 by nonisotopic in situ hybridization | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Dermatology, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Radiation Oncology and Human Genetics, The University of Michigan Medical School, 1150 West Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1321791 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47631/1/439_2004_Article_BF00219171.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00219171 | en_US |
dc.identifier.source | Human Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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