Now showing items 1-10 of 10
Computer aided analysis for biosensing and screening
(Wiley Subscription Services, Inc., A Wiley Company, 1988-02-20)
Biosensors with animal and microbial cells immobilized close to the tip of a membrane electrode have been developed for chemical and drug testing. Our experimental results show that biosensors can be used for drug screening ...
Fermentation monitoring by polymeric-resin-based microbiol assay
(Wiley Subscription Services, Inc., A Wiley Company, 1983-03)
A polymeric-resin-based microbiological assay is shown to yield results consistent with classical inhibition zone theory. This novel assay is applicable to cycloheximide, an antifungal antibiotic, at concentrations below ...
Cell immobilization in k -carrageenan with tricalcium phosphate
(Wiley Subscription Services, Inc., A Wiley Company, 1982-08)
The objectives of this research were to investigate the growth of immobilized yeast cells in k -carrageenan gel and study the effect of trapping hydroxyapatite (tricalcium phosphate) crystals into the matrix. Using k ...
Modeling and prediction of specific compound adsorption by activated carbon and synthetic adsorbents
(Elsevier, 1980)
The performance characteristics of two activated carbons and eight synthetic adsorbents are compared. The comparison addresses both the equilibrium capacities and mass transport properties of the adsorbents. A new empirical ...
Computer modeling of antibiotic fermentation with on-line product removal
(Wiley Subscription Services, Inc., A Wiley Company, 1988-07-20)
The fermentation of Streptomyces griseus for the production of cycloheximide is similar to other antibiotic fermentations in that product synthesis is subject to feedback regulation and the desired product is degraded ...
A new isolation and purification method for staphylococcal protein A using membrane encapsulated rabbit IgG-agarose
(Wiley Subscription Services, Inc., A Wiley Company, 1989-10-20)
A new isolation and purification method for bioproducts using membrane-encapsulated affinity adsorbents was investigated. The new method involves encapsulation of affinity adsorbents, batch adsorption of the bioproduct ...
Application of affinity adsorption in thienamycin fermentation
(Springer-Verlag, 1989-02)
Many antibiotic fermentations are sensitive to high concentrations of their own product possibly due to product regulation and toxicity mechanisms. In this paper we discuss the feasibility of using affinity adsorption with ...
Protein release from Escherichia coli cells permeabilized with guanidine–HCl and Triton X100
(Wiley Subscription Services, Inc., A Wiley Company, 1989-02-20)
An important factor complicating the recovery of recombinant proteins from Escherichia coli is their intracellular location. An alternative to the commonly used method of releasing these proteins by mechanical disruption ...
Interaction of infectious viral particles with a quaternary ammonium chlorid (QAC) surface
(Wiley Subscription Services, Inc., A Wiley Company, 1989-08-20)
The antiviral activity of a surface-bonded quaternary ammonium chloride (QAC) was examined in this study. The mechanism of inactivation was elucidated by a combination of infectivity assay, radioactive labeling assay, and ...
Phosphate feeding to permit growth while maintaining secondary product synthesis
(Springer-Verlag, 1988-02)
Maintaining high metabolic activities for extended periods by feeding small amounts of the growth limiting nutrient was examined for the production of cycloheximide by Streptomyces griseus . Batch studies indicated that ...