Cydophosphamide-Induced Abnormalities in the Incisors of the Rat
dc.contributor.author | Lee Vahlsing, H. | en_US |
dc.contributor.author | Kim, Sun-Kee | en_US |
dc.contributor.author | Feringa, Earl R. | en_US |
dc.date.accessioned | 2010-04-13T19:29:22Z | |
dc.date.available | 2010-04-13T19:29:22Z | |
dc.date.issued | 1977 | en_US |
dc.identifier.citation | Lee Vahlsing, H.; Kim, Sun-Kee; Feringa, Earl (1977). "Cydophosphamide-Induced Abnormalities in the Incisors of the Rat." Journal of Dental Research 7(56): 809-816. <http://hdl.handle.net/2027.42/67458> | en_US |
dc.identifier.issn | 0022-0345 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/67458 | |
dc.description.abstract | A single injection of 75 mg/kg cyclophosphamide caused gross dental abnormalities in rats. Broken, malformed, overgrown, and "extra" incisors developed several weeks after drug treatment. Radioautographic investigations show no unusual features in the morphology or labeling with H3-thymidine in the odontogenic cells. The results suggest that the cytotoxic effect of the drug is a temporary one which induces a residual alteration of tooth growth. | en_US |
dc.format.extent | 3108 bytes | |
dc.format.extent | 1075753 bytes | |
dc.format.mimetype | text/plain | |
dc.format.mimetype | application/pdf | |
dc.publisher | SAGE Publications | en_US |
dc.title | Cydophosphamide-Induced Abnormalities in the Incisors of the Rat | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Veterans Administration Hospital, Ann Arbor, Michigan48105 USA, Departments of Neurology, Pathology, and Anatomy, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Veterans Administration Hospital, Ann Arbor, Michigan48105 USA, Departments of Neurology, Pathology, and Anatomy, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Veterans Administration Hospital, Ann Arbor, Michigan48105 USA, Departments of Neurology, Pathology, and Anatomy, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/67458/2/10.1177_00220345770560071601.pdf | |
dc.identifier.doi | 10.1177/00220345770560071601 | en_US |
dc.identifier.citedreference | Livingston, R.B., and Carter, S.K.: Single Agent in Cancer Chemotherapy, New York, Plenum Publishing Corp., 1970. | en_US |
dc.identifier.citedreference | Brookes, P.: Reaction of Alkylating Agents with Nucleic Acids, In Plattner, P.A. (ed.), Proceedings of International Symposium on Chemotherapy of Cancer, Lugano, Amsterdam, Elsevier, pp 32-43, 1964. | en_US |
dc.identifier.citedreference | Lane, M.: Preliminary Report of Animal Studies with Cytoxan (Cyclophosphamide), Cancer Chemother Rep 3:1-5, 1959. | en_US |
dc.identifier.citedreference | Paterson, P.Y., and Hanson, M.A.: Cyclophosphamide Inhibition of Experimental Allergic Encephalomyelitis and Cellular Transfer of the Disease in Wistar Rats, J Immunol 103:795-806, 1969. | en_US |
dc.identifier.citedreference | Feringa, E.R. ; Wendt, J.S.; and Johnson, R.D.: Immunosuppressive Treatment to Enhance Spinal Cord Regeneration in Rats, Neurology (Minneap) 24:287-293, 1975. | en_US |
dc.identifier.citedreference | Miller, E.E., and Tsou, K.C.: Comparative Study of Lymphoma-Bearing Rats Treated with DAAP, DMAP, Cytoxan, Proc Am Assoc Cancer Res 7:50, 1966. | en_US |
dc.identifier.citedreference | Stenram, U., and Nordlinder, H.: Delayed Death in Rats Treated with Cyclophosphamide, Nature 219: 1154, 1968. | en_US |
dc.identifier.citedreference | Vahlsing, H.L. ; Feringa, E.R. ; Britten, A.G.; and Kinning, W.K.: Dental Abnormalities in Rats After a Single Large Dose of Cyclophosphamide, Cancer Research 35: 2199-2204, 1975. | en_US |
dc.identifier.citedreference | Smith, C.E., and Warshawsky, H.: Cellular Renewal in the Enamel Organ and the Odontoblast Layer of the Rat Incisor as Followed by Radioautography Using 3H-Thymidine, Anat Rec 183:523-561, 1975. | en_US |
dc.identifier.citedreference | Koppang, H.S. : Histomorphologic Investigations on the Effect of Cyclophosphamide on Dentinogenesis of the Rat Incisor, Scand J Dent Res 81: 383-396, 1973. | en_US |
dc.identifier.citedreference | Koppang, H.S. : Autoradiographic Investigations on the Effect of Cyclophosphamide on Dentinogenesis of the Rat Incisor, Scand J Dent Res 81 :397-405, 1973. | en_US |
dc.identifier.citedreference | Adatia, A.K. : The Effects of Cyclophosphamide on Odontogenesis in the Rat, Arch Oral Biol 20:141-144, 1975. | en_US |
dc.identifier.citedreference | Adatia, A.K. : Burkitt's Tumor in the Jaws, Brit Dent J 120:315-326, 1966. | en_US |
dc.identifier.citedreference | Adatia, A.K. : Response of the Dental Elements to Chemotherapy of Burkitt's Tumor, Int Dent J 18:646-653, 1968. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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