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Now showing items 1-22 of 22

    • AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains 
      Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P; Goate, Alison; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack, Clifford R.; Fitzpatrick, Colleen D; McDade, Eric; Chui, Helena C; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M; Hassenstab, Jason J.; Levin, Johannes; Morris, John C.; Johnson, Keith A.; Liu, Lei; Farlow, Martin R.; Jucker, Mathias; Farrell, Michelle E.; Graff-Radford, Neill R.; Joseph-Mathurin, Nelly; Fox, Nick C; Schofield, Peter R; Martins, Ralph N; Sanchez-Valle, Raquel; Perrin, Richard J.; Berman, Sarah; Salloway, Stephen P.; Shirzadi, Zahra; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Bateman, Randall J.; Sperling, Reisa A.; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)
      PDF file (1.7MB)

    • AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains. 
      Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P.; Goate, Alison; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack, Clifford R.; Fitzpatrick, Colleen D; McDade, Eric; Chui, Helena C; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M; Hassenstab, Jason J.; Levin, Johannes; Morris, John C.; Johnson, Keith A.; Liu, Lei; Farlow, Martin R.; Jucker, Mathias; Farrell, Michelle E.; Graff-Radford, Neill R.; Joseph-Mathurin, Nelly; Fox, Nick C; Schofield, Peter R; Martins, Ralph N; Sanchez-Valle, Raquel; Perrin, Richard J.; Berman, Sarah; Salloway, Stephen P.; Shirzadi, Zahra; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Bateman, Randall J.; Sperling, Reisa A.; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)
      PDF file (1.3MB)

    • [ICâ Pâ 166]: UTILITY OF PERFUSION PET MODELS AS MEASURE OF NEURODEGENERATION IN AN AUTOSOMAL DOMINANT ALZHEIMER’s DISEASE POPULATION: REPORT FROM THE DIAN STUDY 
      Joseph‐mathurin, Nelly; Su, Yi; Blazey, Tyler; Jasielec, Mateusz S.; Vlassenko, Andrei G.; Friedrichsen, Karl A.; Gordon, Brian A.; Hornbeck, Russ C.; Cash, Lisa; Ances, Beau M.; Raichle, Marcus E.; Brickman, Adam M.; Buckles, Virginia; Cairns, Nigel J.; Cruchaga, Carlos; Fagan, Anne M.; Goate, Alison; Jack, Clifford R.; Klunk, Bill E.; Koeppe, Robert A.; Marcus, Daniel S.; Mayeux, Richard; McDade, Eric; Paumier, Katrina L.; Ringman, John M.; Saykin, Andrew J.; Thompson, Paul M.; Xiong, Chengjie; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S. (Wiley Periodicals, Inc.The Alzheimer’s Association, Inc., 2017-07)
      PDF file (755.3KB)

    • IC‐P‐020: A voxel‐based morphometry study of volumetric MRI in familial Alzheimer’s disease 
      Cash, David; Ridgway, Gerard; Ryan, Natalie; Kinnunen, Kirsi; Yeatman, Tom; Malone, Ian; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marc; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Salloway, Stephen; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Masters, Colin; Rowe, Christopher; Villemagne, Victor; Martins, Ralph; Brickman, Adam; Mayeux, Richard; Weiner, Michael; Bateman, Randall; Goate, Alison; Fagan, Anne; Xiong, Chengjie; Cairns, Nigel; Buckles, Virginia; Moulder, Krista; Morris, John; Rossor, Martin; Ourselin, Sebastien; Fox, Nick (Wiley Periodicals, Inc., 2012-07)
      PDF file (132.1KB)

    • IC‐P‐032: Cross‐sectional cerebral volumetric differences and associations with estimated time to age‐at‐onset in familial Alzheimer’s disease: Findings from the DIAN study 
      Kinnunen, Kirsi; Cash, David; Liang, Yuying; Leung, Kelvin; Cardoso, Manuel; Modat, Marc; Malone, Ian; Yeatman, Tom; Nicholas, Jennifer; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marcus; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Ghetti, Bernardino; Salloway, Stephen; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Rowe, Christopher; Masters, Colin; Villemagne, Victor; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Weiner, Michael; Bateman, Randall; Goate, Alison; Buckles, Virginia; Moulder, Krista; Morris, John; Rossor, Martin; Ourselin, Sebastien; Fox, Nick (Wiley Periodicals, Inc., 2012-07)
      PDF file (95.6KB)

    • IC‐P‐051: Amyloid load increase and cerebral microbleed prevalence differ as a function of the position of the mutation within the PSEN1 coding sequence 
      Joseph-Mathurin, Nelly; Tang, Mengxuan; Friedrichsen, Karl A.; Owen, Christopher J.; Su, Yi; Hornbeck, Russ C.; Stevenson, Trish A.; Cash, Lisa; Raichle, Marcus E.; Gordon, Brian; Preboske, Gregory M.; Koeppe, Robert A.; Jack, Clifford R.; Goate, Alison; Cruchaga, Carlos; Xiong, Chengjie; Moulder, Krista L.; Buckles, Virginia; Bateman, Randall; Morris, John C.; Benzinger, Tammie L.S. (Wiley Periodicals, Inc.Elsevier B.V., 2015-07)
      PDF file (65.7KB)

    • IC‐P‐082: Disrupted functional connectivity in autosomal dominant Alzheimer’s disease demonstrates network specificity and precedes brain volume loss: Findings from DIAN 
      Chhatwal, Jasmeer; Schultz, Aaron; Johnson, Keith; Benzinger, Tammie; Jack, Clifford; Ances, Beau; Sullivan, Caroline; Salloway, Stephen; Ringman, John; Koeppe, Robert; Marcus, Daniel; Thompson, Paul; Saykin, Andrew; Correia, Stephen; Schofield, Peter; Rowe, Christopher; Fox, Nick; Brickman, Adam; Mayeux, Richard; McDade, Eric; Bateman, Randall; Goate, Alison; Xiong, Chengjie; Buckles, Virginia; Morris, John; Sperling, Reisa (The Alzheimer's Association, Inc.Wiley Periodicals, Inc., 2013-07)
      PDF file (184.1KB)

    • IC‐P‐099: Elevated PiB precedes dementia in autosomal dominant Alzheimer’s disease: PiB, FDG and atrophy in the DIAN cohort 
      Benzinger, Tammie; Blazey, Tyler; Koeppe, Robert; Jack, Clifford; Raichle, Marcus; Su, Yi; Snyder, Abraham; Marcus, Daniel; Ringman, John; Thompson, Paul; Ghetti, Bernardino; Saykin, Andrew; Salloway, Stephen; Correia, Steve; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Masters, Colin; Rowe, Christopher; Villemagne, Victor; Fox, Nick; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Mathis, Chester; Klunk, William; Weiner, Michael; Bateman, Randall; Fagan, Anne; Goate, Alison; Cairns, Nigel; Buckles, Virginia; Moulder, Krista; Morris, John (Wiley Periodicals, Inc., 2012-07)
      PDF file (149KB)

    • IC‐P‐138: Brain and hippocampal rates of atrophy in familial Alzheimer’s disease mutation carriers: Preliminary findings from the DIAN study 
      Kinnunen, Kirsi; Cash, David; Leung, Kelvin; Liang, Yuying; Cardoso, Manuel; Modat, Marc; Malone, Ian; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marcus; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Ghetti, Bernardino; Salloway, Stephen; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Rowe, Christopher; Masters, Colin; Villemagne, Victor; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Weiner, Michael; Bateman, Randall; Goate, Alison; Moulder, Krista; Morris, John; Rossor, Martin; Ourselin, Sebastien; Fox, Nick (Wiley Periodicals, Inc., 2012-07)
      PDF file (118.1KB)

    • O1‐02‐03: Dian‐Tu Adaptive Prevention Trial Launch And Baseline Data 
      Bateman, Randall J.; Mills, Susan; Santacruz, Anna; Farlow, Martin R.; Salloway, Stephen; Morris, John C.; Benzinger, Tammie L.S.; Fagan, Anne M.; Goate, Alison; Hassenstab, Jason; Wang, Guoqiao; Xiong, Chengjie; Jack, Clifford R.; Koeppe, Bob; Martenyi, Ferenc; Searle, Alison; Yaari, Roy; Siemers, Eric; McDade, Eric; Clifford, David (Elsevier B.V.Wiley Periodicals, Inc., 2018-07)
      PDF file (138.2KB)

    • O2‐01‐03: Amyloid load increase and cerebral microbleed prevalence differ as a function of the position of the mutation within the PSEN1 coding sequence 
      Joseph-Mathurin, Nelly; Tang, Mengxuan; Friedrichsen, Karl A.; Owen, Christopher J.; Su, Yi; Hornbeck, Russ C.; Stevenson, Trish A.; Cash, Lisa; Raichle, Marcus E.; Gordon, Brian; Preboske, Gregory M.; Koeppe, Robert A.; Jack, Clifford R.; Goate, Alison; Cruchaga, Carlos; Xiong, Chengjie; Moulder, Krista L.; Buckles, Virginia; Bateman, Randall; Morris, John C.; Benzinger, Tammie L.S. (Wiley Periodicals, Inc.Elsevier B.V., 2015-07)
      PDF file (203.5KB)

    • O2‐06‐01: Disrupted functional connectivity in autosomal dominant Alzheimer’s disease: Preliminary findings from the DIAN study 
      Chhatwal, Jasmeer; Schultz, Aaron; Johnson, Keith; Benzinger, Tammie; Jack, Clifford; Salloway, Stephen; Ringman, John; Koeppe, Robert; Marcus, Daniel; Thompson, Paul; Saykin, Andrew; Correia, Stephen; Schofield, Peter; Rowe, Christopher; Fox, Nick; Brickman, Adam; Mayeux, Richard; Mathis, Chester; Weiner, Michael; Fagan, Anne; Goate, Alison; Cairns, Nigel; Xiong, Chengjie; Masters, Colin; Ghetti, Bernardino; Moulder, Krista; Martins, Ralph; Bateman, Randall; Buckles, Virginia; Morris, John; Sperling, Reisa (Wiley Periodicals, Inc., 2012-07)
      PDF file (132.3KB)

    • O2‐06‐02: FDG metabolism in the DIAN study of autosomal dominant Alzheimer’s disease 
      Becker, John; Koeppe, Robert; Benzinger, Tammie; Jack, Clifford; Marcus, Daniel; Raichle, Marc; Thompson, Paul; Saykin, Andrew; Correia, Stephen; Schofield, Peter; Rowe, Christopher; Fox, Nick; Brickman, Adam; Ghetti, Bernardino; Masters, Colin; Mathis, Chester; Weiner, Michael; Bateman, Randall; Fagan, Anne; Goate, Alison; Xiong, Chengjie; Buckles, Virginia; Moulder, Krista; Mayeux, Richard; Martins, Ralph; Cairns, Nigel; Ringman, John; Salloway, Stephen; Morris, John; Sperling, Reisa; Johnson, Keith (Wiley Periodicals, Inc., 2012-07)
      PDF file (173.4KB)

    • O2‐06‐05: A voxel‐based morphometry study of volumetric MRI in familial Alzheimer’s disease 
      Cash, David; Ridgway, Gerard; Ryan, Natalie; Kinnunen, Kirsi; Yeatman, Tom; Malone, Ian; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marc; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Salloway, Steven; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Masters, Colin; Rowe, Christopher; Villemagne, Victor; Martins, Ralph; Brickman, Adam; Mayeux, Richard; Weiner, Michael; Bateman, Randall; Goate, Alison; Fagan, Anne; Xiong, Chengjie; Cairns, Nigel; Buckles, Virginia; Moulder, Krista; Morris, John; Rossor, Martin; Ourselin, Sebastien; Fox, Nick (Wiley Periodicals, Inc., 2012-07)
      PDF file (156.4KB)

    • O4–03–03: Disrupted functional connectivity in autosomal dominant Alzheimer’s disease demonstrates network specificity and precedes brain volume loss: Findings from the Dominantly Inherited Alzheimer Network 
      Chhatwal, Jasmeer; Schultz, Aaron; Johnson, Keith; Benzinger, Tammie; Jack, Clifford; Ances, Beau; Sullivan, Caroline; Salloway, Stephen; Ringman, John; Koeppe, Robert; Marcus, Daniel; Thompson, Paul; Saykin, Andrew; Correia, Stephen; Schofield, Peter; Rowe, Christopher; Fox, Nick; Brickman, Adam; Mayeux, Richard; McDade, Eric; Bateman, Randall; Goate, Alison; Xiong, Chengjie; Buckles, Virginia; Morris, John; Sperling, Reisa (Wiley Periodicals, Inc.The Alzheimer's Association, Inc., 2013-07)
      PDF file (379.9KB)

    • P1‐015: Brain and hippocampal rates of atrophy in familial Alzheimer’s disease mutation carriers: Preliminary findings from the DIAN study 
      Kinnunen, Kirsi; Cash, David; Leung, Kelvin; Liang, Yuying; Cardoso, Manuel; Modat, Marc; Malone, Ian; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marc; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Ghetti, Bernardino; Salloway, Stephen; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Rowe, Christopher; Masters, Colin; Villemagne, Victor; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Weiner, Michael; Bateman, Randall; Goate, Alison; Buckles, Virginia; Moulder, Krista; Morris, John; Rossor, Martin; Ourselin, Sebastien; Fox, Nick (Wiley Periodicals, Inc., 2012-07)
      PDF file (78.5KB)

    • [P2â 372]: UTILITY OF PERFUSION PET MODELS AS MEASURES OF NEURODEGENERATION IN AN AUTOSOMAL DOMINANT ALZHEIMER’s DISEASE POPULATION: REPORT FROM THE DIAN STUDY 
      Joseph‐mathurin, Nelly; Su, Yi; Blazey, Tyler; Jasielec, Mateusz S.; Vlassenko, Andrei G.; Friedrichsen, Karl A.; Gordon, Brian A.; Hornbeck, Russ C.; Cash, Lisa; Ances, Beau M.; Raichle, Marcus E.; Brickman, Adam M.; Buckles, Virginia; Cairns, Nigel J.; Cruchaga, Carlos; Fagan, Anne M.; Goate, Alison; Jack, Clifford R.; Klunk, Bill E.; Koeppe, Robert A.; Marcus, Daniel S.; Mayeux, Richard; McDade, Eric; Paumier, Katrina L.; Ringman, John M.; Saykin, Andrew J.; Thompson, Paul M.; Xiong, Chengjie; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S. (Wiley Periodicals, Inc.The Alzheimer’s Association, Inc., 2017-07)
      PDF file (912.5KB)

    • P2‐226: Cross‐sectional cerebral volumetric differences and associations with estimated time to age‐at‐onset in familial Alzheimer’s disease: Findings from the DIAN study 
      Kinnunen, Kirsi; Cash, David; Liang, Yuying; Leung, Kelvin; Cardoso, Jorge; Modat, Marc; Malone, Ian; Yeatman, Tom; Nicholas, Jennifer; Benzinger, Tammie; Koeppe, Robert; Jack, Clifford; Raichle, Marc; Marcus, Daniel; Ringman, John; Thompson, Paul; Saykin, Andrew; Ghetti, Bernardino; Salloway, Stephen; Correia, Stephen; Johnson, Keith; Sperling, Reisa; Schofield, Peter; Rowe, Christopher; Masters, Colin; Villemagne, Victor; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Weiner, Michael; Bateman, Randall; Goate, Alison; Buckles, Virginia; Moulder, Krista; Morris, John; Rossor, Martin; Fox, Nick; Ourselin, Sebastien (Wiley Periodicals, Inc., 2012-07)
      PDF file (110.4KB)

    • P4‐153: Elevated PiB precedes dementia in autosomal‐dominant Alzheimer’s disease: PiB, FDG and atrophy in the DIAN cohort 
      Benzinger, Tammie; Blazey, Tyler; Koeppe, Robert; Jack, Clifford; Raichle, Marc; Su, Yi; Snyder, Abraham; Marcus, Daniel; Johnson, Keith; Sperling, Reisa; Ringman, John; Thompson, Paul; Ghetti, Bernardino; Saykin, Andrew; Schofield, Peter; Masters, Colin; Rowe, Christopher; Fox, Nick; Brickman, Adam; Mayeux, Richard; Martins, Ralph; Mathis, Chester; Klunk, William; Weiner, Michael; Bateman, Randall; Fagan, Anne; Goate, Alison; Cairns, Nigel; Buckles, Virginia; Moulder, Krista; Villemagne, Victor; Morris, John (Wiley Periodicals, Inc., 2012-07)
      PDF file (93.4KB)

    • Progressive white matter injury in autosomal dominant Alzheimer’s disease is strongly associated with cerebral microbleeds and neurodegeneration 
      Shirzadi, Zahra; Schultz, Stephanie A.; Yau, Wai-Ying Wendy; Joseph-Mathurin, Nelly; Kantarci, Kejal; Preboske, Gregory M.; Jack, Clifford R.; Farlow, Martin R.; Fagan, Anne M.; Hassenstab, Jason J.; Jucker, Mathias; Morris, John C.; Xiong, Chengjie; Karch, Celeste M.; Fitzpatrick, Colleen D; Levey, Allan I.; Gordon, Brian A.; Schofield, Peter W.; Salloway, Stephen P.; Perrin, Richard J.; McDade, Eric; Levin, Johannes; Cruchaga, Carlos; Allegri, Ricardo Francisco; Fox, Nick C; Goate, Alison; Graff-Radford, Neill R.; Koeppe, Robert; Noble, James M; Chui, Helena C; Berman, Sarah; Mori, Hiroshi; Sanchez-Valle, Raquel; Lee, Jae-Hong; Rosa-Neto, Pedro; Benzinger, Tammie L.S.; Sohrabi, Hamid R; Martins, Ralph N; Schultz, Aaron P.; Bateman, Randall J.; Johnson, Keith A.; Sperling, Reisa A.; Greenberg, Steven M; Chhatwal, Jasmeer P. (Wiley Periodicals, Inc., 2022-12)
      PDF file (1.6MB)

    • Utility of perfusion PET measures to assess neuronal injury in Alzheimer’s disease 
      Joseph‐mathurin, Nelly; Su, Yi; Blazey, Tyler M.; Jasielec, Mateusz; Vlassenko, Andrei; Friedrichsen, Karl; Gordon, Brian A.; Hornbeck, Russ C.; Cash, Lisa; Ances, Beau M.; Veale, Thomas; Cash, David M.; Brickman, Adam M.; Buckles, Virginia; Cairns, Nigel J.; Cruchaga, Carlos; Goate, Alison; Jack, Clifford R.; Karch, Celeste; Klunk, William; Koeppe, Robert A.; Marcus, Daniel S.; Mayeux, Richard; McDade, Eric; Noble, James M.; Ringman, John; Saykin, Andrew J.; Thompson, Paul M.; Xiong, Chengjie; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S. (Wiley Periodicals, Inc., 2018)
      PDF file (1.3MB)

    • White matter hyperintensities are a core feature of Alzheimer’s disease: Evidence from the dominantly inherited Alzheimer network 
      Lee, Seonjoo; Viqar, Fawad; Zimmerman, Molly E.; Narkhede, Atul; Tosto, Giuseppe; Benzinger, Tammie L.S.; Marcus, Daniel S.; Fagan, Anne M.; Goate, Alison; Fox, Nick C.; Cairns, Nigel J.; Holtzman, David M.; Buckles, Virginia; Ghetti, Bernardino; McDade, Eric; Martins, Ralph N.; Saykin, Andrew J.; Masters, Colin L.; Ringman, John M.; Ryan, Natalie S.; Förster, Stefan; Laske, Christoph; Schofield, Peter R.; Sperling, Reisa A.; Salloway, Stephen; Correia, Stephen; Jack, Clifford; Weiner, Michael; Bateman, Randall J.; Morris, John C.; Mayeux, Richard; Brickman, Adam M. (Wiley Periodicals, Inc., 2016-06)
      PDF file (441.4KB) PDF file (3.8MB)