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- Creator:
- Wilson Mantilla, Jeffrey A.
- Description:
- The 3D model of the humerus was created from an isolated element that is referred to the pterosaur Arambourgiania philadelphiae. The element is accessioned to Yarmouk University (YUPC-RUSEIFA-1) in the Hashemite Kingdom of Jordan. The specimen was collected from Late Cretaceous-aged sediments at the Ruseifa Quarry in central Jordan. For inquiries about access to the specimen, please contact Jeff Wilson Mantilla ( wilsonja@umich.edu) or Iyad Zalmout ( izalmout@ksu.edu.sa). Casts of this element of Arambourgiania are available at the University of Michigan Museum of Paleontology.
- Keyword:
- Jordan pterosaur cretaceous vertebrate gondwana afro-arabia paleontology
- Citation to related publication:
- Rosenbach, K. L., D. M. Goodvin, M. G. Albshysh, H. A. Azzam, A. A. Smadi, H. A. Mustafa, I. S. A. Zalmout, and J. A. Wilson Mantilla. [in press] New pterosaur remains from the Late Cretaceous of Afro-Arabia provide insight into flight capacity of large pterosaurs. Journal of Vertebrate Paleontology.
- Discipline:
- Science
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- Creator:
- Wilson Mantilla, Jeffrey A.
- Description:
- The left humerus is part of an associated skeleton of the pterosaur Inabtanin alarabia, accessioned to Yarmouk University (YUPC-INAB-6-001–010) in the Hashemite Kingdom of Jordan. The specimen was collected from Late Cretaceous-aged sediments near Tal Inab in south-central Jordan, which is 34 km north of the current border with Saudi Arabia. For inquiries about access, please contact Jeff Wilson Mantilla ( wilsonja@umich.edu) or Iyad Zalmout ( izalmout@ksu.edu.sa). Casts of this and other elements of Inabtanin alarabia are available at the University of Michigan Museum of Paleontology.
- Keyword:
- Jordan pterosaur cretaceous vertebrate gondwana afro-arabia paleontology
- Citation to related publication:
- Rosenbach, K. L., D. M. Goodvin, M. G. Albshysh, H. A. Azzam, A. A. Smadi, H. A. Mustafa, I. S. A. Zalmout, and J. A. Wilson Mantilla. [in press] New pterosaur remains from the Late Cretaceous of Afro-Arabia provide insight into flight capacity of large pterosaurs. Journal of Vertebrate Paleontology.
- Discipline:
- Science
-
- Creator:
- Hutson, Abby , Fujisaki-Manome, Ayumi, and Glassman, Ryan
- Description:
- The data herein resulted from a study documenting the characteristics of extratropical cyclones that pass through the Great Lakes Region (GLR) and how the cyclones are trending with time. All scripts used to create these data can be found in the Github repository https://github.com/abkenyon/GLStormTrends_2024. storm_track_slp_xxxx.npz - Structured numpy files containing all storm tracks identified over one cold season, regardless of whether the storm encountered the GLR, with the file name indicating the year on which the season ended. storm_composite_xxxx-xxxx.nc - NetCDF files containing one seasonal cyclone composite with different atmospheric variables. A composite is storm-centered, and covers a 20 degree square area.
- Keyword:
- Extratropical Cyclones, Climate Trends, Great Lakes Climate
- Citation to related publication:
- Hutson A, Fujisaki-Manome A, Glassman R.: Historical Trends in Cold-Season Mid-Latitude Cyclones. Geophysical Research Letters. In press..
- Discipline:
- Science
-
- Creator:
- Sosa Alfaro, Victor, Palomino, Hannah, Liu, Sophia, Lemuh Njimoh, Cybele, and Lehnert, Nicolai
- Description:
- Pharmaceutical synthesis has been a driving force behind advancements in the field of biocatalysis. In this paper, we report the further optimization of the heme protein YfeX for regio- and stereoselective carbene transfer reactions using mutagenesis to explore the role of important amino acids in the active site for catalysis. In this way, we identified YfeX variants that are efficient and selective carbene transferases towards primary and secondary amines, olefins, and indoles. Molecular Dynamic simulations reveal that mutations within the secondary coordination sphere induce distinct alterations in the conformation and electrostatic properties within the active site. These changes, in turn, affect substrate positioning both within the active site and at its entrance, which explains the distinct and sometimes surprising variations in selectivity observed experimentally between select YfeX variants. Our results show that the I230A single variant identified here is one of the most active N-H insertion catalysts known, producing >90% yields in only 1 hour (typical reaction times in the literature are 8 – 24 hours). On the other hand, the R232A variant catalyzes the C-H insertion of unprotected indole in 21% yield. The capacity to selectively act on unprotected indole offers a cost-effective, environmentally-friendly approach for late-stage functionalization of indoles and similar precursors in pharmaceuticals. In addition, YfeX is an efficient and fast biocatalyst that shows no structural degradation or heme loss during turnover, underscoring YfeX’s robustness as a viable biocatalyst for both industrial and academic applications.
- Keyword:
- Biocatalysis, Heme proteins, Carbene transfer reactions, Peroxidases , N-H insertion, Cyclopropanation, and Molecular dynamics
- Citation to related publication:
- Sosa Alfaro, Victor; Palomino, Hannah; Liu, Sophia; Lemuh Njimoh, Cybele; Lehnert, Nicolai, "Combined Experimental and Molecular Dynamics Approach Towards a Rational Design of the YfeX Biocatalyst for Enhanced Carbene Transferase Reactivity", Catalysis Science & Technology 2024, 14, DOI: 10.1039/D3CY01489D
- Discipline:
- Science
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- Creator:
- Whittaker, Collin B. and Jorns, Benjamin A.
- Description:
- This work characterized variability in the emitter geometry of a porous electrospray array thruster. It consists of raw topographic maps taken from the thruster, segmented versions of those maps that divide the measurement domain into individual sites within the array, and the geometric parameters describing each of those sites inferred by regressing a geometric model of an emitter against the data. It also includes copies of the computer code used to perform this analysis and plot the results, written in a combination of Python and MATLAB.
- Discipline:
- Engineering
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- Creator:
- Shin, Satbyeol and Gronewold, Andrew D.
- Description:
- - Temporal coverage: 1/1/1941 to 12/31/2020 - Spatial coverage: Entire Great Lakes basin - Output format: The original modeling outputs are provided at a 1 km/daily resolution in NetCDF format. There are two kinds of modeling outputs, which are land surface modeling outputs (LDASOUT) and hydrological modeling outputs (CHRTOUT). The author recommend using the netCDF Operators (NCO) program for data processing. For visualization and plotting, the author recommend using software like MATLAB, Python or R.
- Keyword:
- Hydrologic modeling, Overland precipitation, Air temperature, Evapotranspiration, Snow Water Equivalent, Runoff, Surface Soil moisture, St. Lawrence river, Great Lakes basin, Reanalysis data, WRF-Hydro, and ERA-5
- Discipline:
- Science
-
- Creator:
- El Shair, Zaid A., Abu-raddaha, Abdalmalek , Cofield, Aaron, Alawneh, Hisham, Aladem, Mohamed, Hamzeh, Yazan, and Rawashdeh, Samir A.
- Description:
- The SID dataset was curated to support advanced research in autonomous driving systems, particularly focusing on perception under adverse weather and lighting conditions. This dataset encompasses over 178k high-resolution stereo image pairs organized into 27 sequences, reflecting a rich variety of conditions such as snow, rain, fog, and low light. It covers dynamic changes in driving scenarios and environmental backgrounds, including university campuses, residential streets, and urban settings. The dataset is designed to challenge perception algorithms with scenarios such as partially obscured camera lenses and varying visibility, promoting the development of robust computer vision models. No specialized software or scripts are necessary for accessing the image data, as the files are provided in standard PNG format. However, researchers and developers may require their image processing and computer vision toolkits to utilize the dataset effectively in their work.
- Keyword:
- Autonomous Driving, Adverse Weather, Stereo Vision, Image Dataset, Computer Vision, and Perception Algorithms
- Citation to related publication:
- El-Shair, Z.A., Abu-raddaha, A., Cofield, A., Alawneh, H., Aladem, M., Hamzeh, Y., and Rawashdeh, S.A., 2024. SID: Stereo Image Dataset for Autonomous Driving in Adverse Conditions. In 2024 IEEE National Aerospace and Electronics Conference (NAECON). IEEE. In press.
- Discipline:
- Engineering
-
- Creator:
- Fahim, Abigail T
- Description:
- The purpose of this research is to compare levels of unprenylated Rab proteins in CHM-/- iPSC-RPE cells with and without compactin. Compactin is a statin that inhibits prenyl synthesis and thereby reduces prenylation overall and has an unbiased inhibitory effect on all protein prenylation. So we expect that for Rabs that are already poorly prenylated at baseline in choroideremia RPE cells, compactin will have minimal effect. However, for Rabs that are efficiently prenylated at baseline, compactin should have a much greater effect. And then we used tandem mass tag spectrometry to compare the ratio of each unprenylated Rab in compactin-treated choroideremia cells vs untreated choroideremia cells. In the spreadsheet, "F8" refers to the CHM-/- iPSC-RPE cells and "WT" refers to the isogenic control iPSC-RPE cells. In the "Proteins only" tab, column M shows the ratio of each protein in "DMSO" (untreated) choroideremia cells compared to Compactin-treated choroideremia cells. Compactin-treated control cells are also included in other columns. Untreated control cells could not be used because prenylation is so efficient in these cells, there is almost no material available after doing the in vitro prenylation assay (i.e. almost no unprenylated proteins to biotinylate). The column descriptions can be found in the sheet titled "Explanations." In addition, AAs= number of amino acids in the protein, MW= molecular weight of the protein, and pI= isoelectric point. The software is set to report abundance values only when certain criteria are met (S/N of 6, unique peptide etc). A value is NOT reported when the data for a protein fall below these criteria and the cell is instead left blank.
- Keyword:
- choroideremia, retinal pigment epithelium, prenylation, and Rab protein
- Citation to related publication:
- Raeker, M.O., Perera, N.D., Karoukis, A.J., Chen, L., Feathers, K.L., Ali, R.R., Thompson, D.A., Fahim, A.T. Reduced retinal pigment epithelial autophagy due to loss of Rab12 prenylation in a human iPSC-RPE model of choroideremia. Cells, manuscript accepted, in press.
- Discipline:
- Health Sciences and Science
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- Creator:
- Marks, Thomas A and Gorodetsky, Alex A
- Description:
- WarpX simulations of the 2D axial-azimuthal Hall thruster benchmark, as described in IEPC paper 409 (2024): https://www.thomasmarks.space/files/Marks_T_IEPC_2024_WarpX.pdf Contains one subdirectory: baseline_20us: 20 us of data, saved every 5000 iterations (32 GB) The data is in AMReX plotfile format.
- Keyword:
- hall thruster, plasma, pic, particle in cell, particle, cell, kinetic, electric propulsion, and thruster
- Citation to related publication:
- @inproceedings{marksWarpX2024, title = {Hall thruster simulations in {{Warp-X}}}, booktitle = {38th {{International Electric Propulsion Conference}}}, author = {Marks, Thomas A. and Gorodetsky, Alex A.}, year = {2024}, month = jun, address = {Toulouse, France} }
- Discipline:
- Engineering
-
- Creator:
- El Shair, Zaid A. and Rawashdeh, Samir A.
- Description:
- The MEVDT dataset was created to fill a critical gap in event-based computer vision research by supplying a high-quality, real-world labeled dataset. Intended to facilitate the development of advanced algorithms for object detection and tracking applications, MEVDT includes multi-modal traffic scene data with synchronized grayscale images and high-temporal-resolution event streams. Additionally, it provides annotations for object detection and tracking with class labels, pixel-precise bounding box coordinates, and unique object identifiers. The dataset is organized into directories containing sequences of images and event streams, comprehensive ground truth labels, fixed-duration event samples, and data indexing sets for training and testing. and To access and utilize the dataset, researchers need specific software or scripts compatible with the data formats included, such as PNG for grayscale images, CSV for event stream data, AEDAT for the encoded fixed-duration event samples, and TXT for annotations. Recommended tools include standard image processing libraries for PNG files and CSV or text parsers for event data. A specialized Python script for reading AEDAT files is available at: https://github.com/Zelshair/cstr-event-vision/blob/main/scripts/data_processing/read_aedat.py, which streamlines access to the encoded event sample data.
- Keyword:
- Computer Vision, Event-Based Vision, Object Detection, Object Tracking, and Multi-Modal Vision Dataset
- Citation to related publication:
- El Shair, Z. and Rawashdeh, S., 2024. MEVDT: Multi-Modal Event-Based Vehicle Detection and Tracking Dataset. Data In Brief (under review)., El Shair, Z. and Rawashdeh, S.A., 2022. High-temporal-resolution object detection and tracking using images and events. Journal of Imaging, 8(8), p.210., El Shair, Z. and Rawashdeh, S., 2023. High-temporal-resolution event-based vehicle detection and tracking. Optical Engineering, 62(3), pp.031209-031209., and El Shair, Z.A., 2024. Advancing Neuromorphic Event-Based Vision Methods for Robotic Perception Tasks (Doctoral dissertation, University of Michigan-Dearborn).
- Discipline:
- Engineering