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  • Patient-specific modeling of right coronary circulation vulnerability post-liver transplant in Alagille’s syndrome

    Creator: Figueroa, C. Alberto
    Description: These files and instructions provide the data require to manually setup the computational simulations used in the PLOS ONE paper 'Patient-specific modeling of right coronary circulation vulnerability post-liver transplant in Alagille’s syndrome' using CRIMSON (CARDIOVASCULAR INTEGRATED MODELLING & SIMULATION) a prototype simulation environment developed under the support of the European Research Council ((http://www.crimson.software/). Note that a Windows version of the CRIMSON flowsolver is provided as part of the CRIMSON Windows installer, but you will need a very powerful Windows computer to run these simulations, as the models used in the present work are extremely computationally-demanding. It is recommended that you use a Linux version of the CRIMSON flowsolver on a high-performance computer. Option 1 (ready-to-use files to immediately start the simulation): 1. Please unzip the Ready-to-use files. 2. Copy the folders of each of the three conditions to the high performance computer. 3. In addition to different codes used, each folder provides the boundary conditions applied in the simulations described in the manuscript (e.g. LPN parameters). To run the 3D simulations for each condition simply launch the it using the CRIMSON flowsolver. In addition, the solver.inp file can be modified to run a 0D "real-time simulation" (please open solver.inp with a text editor and modify line 4 "Simulate in Purely Zero Dimensions:" to "True"). Option 2 (using the MITK files): 1. Please download and install Crimson software (http://www.crimson.software/). 2. Please unzip the MITK files and the Ready-to-use files. 3. From amongst the provided MITK files, load the MITK file of interest to CRIMSON (using the MITK files, additional changes can be made to the computational model in case the user wants to explore different settings/boundary conditions e.g. change the vascular wall properties, introducing a change in the geometry to create a virtual stenosis). 3. Navigate to the tree in the "Data Manager" panel and select the "Pulmonaries", "CRIMSON SOLVER" and then "Solver study 3D" items, in the described order. 4. In the right hand panel select the "CRIMSON Solver setup" tab and scroll down the right hand bar until to find the "Setup Solver" box; click to output the simulation files (faceInfo.dat, geombc.dat.1, multidomain.dat, netlist_surface.dat,numstart.dat, presolver folder, solver.inp, restart.0.1). 5. Copy and replace the geombc.dat.1 and restart.0.1 generated by CRIMSON for each individual condition to the respective unziped folder in the Ready-to-use file (discard the remaining files that were output by CRIMSON). Note that if you have not changed anything about the model (e.g. vascular wall properties), then doing this will produce restart.0.1 and geombc.dat.1 files which are identical to the ready-to-use versions. 6. Finally copy each Condition folder to the high performance computer and simply launch the simulation using the CRIMSON flowsolver. For technical queries please contact crimson-users@googlegroups.com. October 2018.
  • Dataset of live-cell movies of single PolC-PAmCherry molecules in Bacillus subtilis cells with high and low fluorescent backgrounds.

    Work
    Creator: Isaacoff, Benjamin P., Li, Yilai, Lee, Stephen A., and Biteen, Julie S.
    Description: This is the experimental data referenced in our manuscript entitled “SMALL-LABS: An algorithm for measuring single molecule intensity and position in the presence of obscuring backgrounds .” These live-cell single-molecule imaging movies were used as a test of the SMALL-LABS single-molecule image analysis algorithm. The dataset comprises two movies; each one is provided both as a .tif stack and as an .avi file. The movie called “low_bg” has a standard low background, and the movie called “high_bg” includes a high fluorescent background produced by an external 488-nm laser.
  • Flowing into the unknown: inferred paleodrainages for studying the ichthyofauna of Brazilian coastal rivers - paleodrainages shapefiles

    Work
    Creator: Thomaz, Andréa T. (UMICH) and Knowles, L. Lacey (UMICH)
    Description: The eastern coastal basins of Brazil are a series of small and isolated rivers that drain directly into the Atlantic Ocean. During the Pleistocene, sea-level retreat caused by glaciations exposed the continental shelf, resulting in enlarged paleodrainages that connected rivers that are isolated today. Using Geographic Information System (GIS), we infer the distribution of these paleodrainages, and their properties for the east Brazilian coast. Here, we publicly make available the shapefiles that demonstrate the paleodrainage structure along the Brazilian coast during the largest sea-level retreats in the Pleistocene, the riverine vectors during the same period and the coastal line for a drop of -125m in the sea.
  • Spatially-explicit model code and outputs of Bighead and Silver carp growth rate potential in Lake Michigan

    Work
    Creator: Alsip, Peter
    Description: Percent Weight Change Data: The model was run continuously on a daily time step for seasonal intervals (Spring: March thru May; Summer: June thru August; Fall: September thru November) as well as contiguously from Spring to Fall to assess total growth over the likely growing season (March thru November). CSV files represent the simulated weight change (%) of Bighead and Silver Carp for the respective time periods associated with the file name. Initial fish mass for each seasonal interval and growing season was 4350 g for Silver Carp and 5480 g for Bighead Carp. Maximum and mean total weight change (%) was determined for three depth ranges (near surface depths [NS]: 0 – 10 m; deep chlorophyll layer depths [DCL]: 10 - 50 m; and whole water column [WC]). Coordinates are in decimal degrees. File naming convention: speciesSeasonWtChange (e.g. bigheadFallWtChange = % weight change of Bighead Carp from September through November) , Monthly Habitat Quality Data: Rdata files contain matrices of Bighead or Silver carp growth rate potential as represented as a mass-proportional growth rate (gram of carp/gram of carp/day [g/g/d]) for the 15th day of each month. Habitats with growth rate potential >= 0 g/g/d were deemed suitable. Matrix attributes: Rows: Row numbers refer to the spatial node with 20 equally-spaced vertical layers. Columns: Columns 1-20 refer to the growth rate potential value for each vertical layer of each node. Vertical layers are evenly spaced based on the total depth of the water column for each node. Depth for each node can be found in the grid attributes data file. Columns 21 ("meanG") and 22 ("Gmax") represent the average and maximum growth rate potential, respectively, of the fish across the whole water column for the corresponding node. File naming convention: species_MonthNumber (e.g. silver_06 = Silver carp growth rate potential in June) Spatial coordinates for each node can be found in the grid attributes data files., Grid attributes data: This Rdata file provides the spatial reference data and other grid attributes. Coordinates are provided in UTM (x & y) and latitude and longitude (decimal degrees). Depth (meters) for each node is listed in this file. , GRP Model code: Details bioenergetics equations, foraging equation, functions for running the model on a monthly time-step and daily time step, and functions for basic analyses. Model is coded in R., and The simulated input data (prey and temperature) used to run our model is not included in this data set. Instead we provide the model code, grid attributes, and outputs of the model. The readRDS() function (R Base Package v.3.5.1) is required to read in .Rdata files in R.
  • Video data of predation and parasitism by arthropods on small vertebrates in lowland Peruvian Amazon

    Work
    Creator: Grundler, Michael C, Grundler, Maggie G, and Herrera, V.
    Description: Nighttime and diurnal surveys in the lowland Peruvian Amazon of Los Amigos Biological Station were conducted in order to describe herpetological diversity at this site. As a result of these surveys, the predation event between a Pamphobeteus sp. and Marmosops sp. and the myiasis of Ranitomeye uakarii were observed. The video footage was recorded in order to document these interesting interactions between arthropod predators and parasites and vertebrate prey and hosts, and are included for publication in the short communication "Ecological interactions between arthropods and small vertebrates in a lowland Amazon rainforest" in the journal Amphibian and Reptile Conservation.
  • Single-molecule microscopy image data and analysis files for "Ultra-specific and Amplification-free Quantification of Mutant DNA by Single-molecule Kinetic Fingerprinting"

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    Creator: Hayward, Stephen L. , Lund, Paul E., Kang, Qing, Johnson-Buck, Alexander , Tewari, Muneesh, and Walter, Nils G.
    Description: This work contains the experimental data and associated analysis that are described in the research publication entitled "Ultra-specific and Amplification-free Quantification of Mutant DNA by Single-molecule Kinetic Fingerprinting". This work contains multiple zip files, each of which represents one of the principal experiment groups presented in the publication. Each experiment group contains movie and analysis files corresponding to various experimental conditions related to that experiment group.
  • Results from simulations of earthquake rupture in fault zones with along-strike heterogeneity

    Work
    Creator: Huang, Yihe
    Description: Geological and geophysical observations reveal along-strike fault zone heterogeneity on major strike-slip faults, which can play a significant role in earthquake rupture propagation and termination. I present 2D dynamic rupture simulations to demonstrate rupture characteristics in such heterogeneous fault zone structure. The modeled rupture is nucleated in a damaged fault zone and propagates on a preexisting fault towards the zone of intact rocks. There is an intermediate range of nucleation lengths that only allow rupture to spontaneously propagate in the damaged fault zone but not in a homogeneous medium. I find that rupture with an intermediate nucleation length tends to stop when it reaches the zone of intact rocks, especially when the rupture propagation distance in the damaged fault zone is relatively short and when the damaged fault zone is relatively narrow or smooth in the fault-normal direction. Pronounced small-scale heterogeneity within the damaged fault zone also contributes to such early rupture termination. In asymmetric fault zones bisected by a bimaterial fault, rupture moving in the direction of slip of faster rocks tends to terminate under the same conditions as in symmetric fault zones, whereas rupture moving in the direction of slip of slower rocks can penetrate into the zone of intact rocks. Break-through rupture is allowed when a sufficiently-large asperity is located at the edge of the zone of intact rocks. The results suggest the along-strike fault zone heterogeneity can play a critical role in seismicity distribution. The data set contains multiple folders of simulation results from the SEM2DPACK that demonstrate the above findings. The folder name includes the model parameters in each simulation as explained in the README file. The Flt01_sem2d.data file in the folder documents the slip, slip rate and stresses from each simulation. The files are also explained in the manual of SEM2DPACK (http://web.gps.caltech.edu/~ampuero/soft/users_guide_sem2dpack.pdf). Please refer to section 4.6 in the manual and use “sem2d_read_fault.m” in the POST folder of SEM2DPACK to plot the results.
  • Anthropogenic Aerosol indirect effects in cirrus clouds

    Work
    Creator: Penner, Joyce E., Zhou, Cheng, Garnier, Anne, and Mitchell, David
    Description: This data set contains the scripts and data sets needed to create the 9 figures in the referenced publication.
  • Central Mali documentary videos

    Creator: Heath, Jeffrey G.
    Description: Short documentary videos of practical activities and cultural events of Dogon, Fulbe, Songhay, and Bangande ethnic groups of eastern Central Mali. The videos were byproducts of linguistic research on the local language. They are presented here in three formats: wmv, avi, and either qt or mov. See the "readme" files in each work for a summary of the videos in it. and The footage was shot with various digital cameras. The oldest videos (2010 and one or two from 2011) were edited using iMovie. The later videos were edited using AVS editing software. Several of the 2010 videos, referred to as "compilations," are simple sequences of short clips that combine to illustrate a complex activity such as extracting oil from nuts. The later videos are in more flowing documentary form with overlaid titles in English. In some cases, vocabulary from the relevant native language is included in the titles.
  • Stewardship Gap Project Bibliography Data

    Work
    Creator: York, Jeremy, Gutmann, Myron, and Berman, Francine
    Description: The data were collected as part of the Stewardship Gap project, an 18-month study to investigate how research data and creative outputs supported by public or non-profit funding in the United States are being stewarded. These data were collected as part of a literature search of sources about research data stewardship and relate most directly to work describing “What We Know About the Stewardship Gap.” In this work, we categorized “gaps” in stewardship identified in the literature, how the gaps were related to one another, and efforts to measure and develop metrics for the gaps.