Investigating minimum human reaction times is often confounded by the motivation, training, and state of arousal of the subjects. We used the reaction times of athletes competing in the shorter sprint events in the Athletics competitions in recent Olympics (2004-2016) to determine minimum human reaction times because there's little question as to their motivation, training, or state of arousal.
The reaction times of sprinters however are only available on the IAAF web page for each individual heat, in each event, at each Olympic. Therefore we compiled all these data into two separate excel sheets which can be used for further analyses.
Mirshams Shahshahani P, Lipps DB, Galecki AT, Ashton-Miller JA (2018) On the apparent decrease in Olympic sprinter reaction times. PLoS ONE 13(6): e0198633. https://doi.org/10.1371/journal.pone.0198633
This data is part of a large program to translate detection and interpretation of HFOs into clinical use. A zip file is included which contains hfo detections, metadata, and Matlab scripts. The matlab scripts analyze this input data and produce figures as in the referenced paper (note: the blind source separation method is stochastic, and so the figures may not be exactly the same). A file "README.txt" provides more detail about each individual file within the zip file.
Stephen V. Gliske, Zachary T. Irwin, Cynthia Chestek, Garnett L. Hegeman, Benjamin Brinkmann, Oren Sagher, Hugh J. L. Garton, Greg A. Worrell, William C. Stacey. "Variability in the location of High Frequency Oscillations during prolonged intracranial EEG recordings." Nature Communications. https://doi.org/10.1038/s41467-018-04549-2
Data reflect the knowledge, attitudes, and beliefs of health care providers regarding neonatal near-misses in Neonatal Intensive Care Units (NICUs) in southern Ghana.
Health status data includes data about the health of persons within a census tract in Metropolitan Detroit, measured at the census tract level. This includes data about 1) mortality by condition; 2) exposures to toxic substances; and 3) disability.
Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
This dataset includes census tract-level data concerning housing in Metropolitan Detroit. The data includes: 1) Total housing units and total mortgages in the tract; 2) Land use; 3) Real estate information (foreclosures, sales transactions, and home values); 4) Vacant housing; 5) Housing age and available facilities; 6) Housing condition; and 7) Spatial measures of subsidized housing in the tract.
Data coverage should say 2006 to 2015.
Contained within is a subset of the larger dataset collected in La Paz, Bolivia in 2014. This data contains the analytic dataset (cross-sectional/descriptive) that includs the PACIC, Morisky, PHQ8, AUDIT, and a subset of socidemographic characteristics for NCD patients in La Paz.
Abbott P, Banerjee T, Aruquipa Yujra AC, Xie B, Piette J (2018) Exploring chronic disease in Bolivia: A cross-sectional study in La Paz. PLOS ONE 13(2): e0189218. https://doi.org/10.1371/journal.pone.0189218
The information and education environment refers to: 1) the presence of information infrastructures such as broadband Internet access and public libraries in a location; 2) a person’s proximity to information infrastructures and sources; 3) the distribution of information infrastructures, sources and in a specific location; and 4) exposure to specific messages (information content) within a specific location.
Coverage for all data: 10-county Detroit-Warren-Ann Arbor Combined Statistical Area.
The rapid activation of the mechanistic target of rapamycin complex-1 (mTORC1) by growth factors is increased by extracellular amino acids through yet-undefined mechanisms of amino acid transfer into endolysosomes. Because the endocytic process of macropinocytosis concentrates extracellular solutes into endolysosomes and is increased in cells stimulated by growth factors or tumor-promoting phorbol esters, we analyzed its role in amino acid–dependent activation of mTORC1. Here, we show that growth factor-dependent activation of mTORC1 by amino acids, but not glucose, requires macropinocytosis. In murine bone marrow–derived macrophages and murine embryonic fibroblasts stimulated with their cognate growth factors or with phorbol myristate acetate, activation of mTORC1 required an Akt-independent vesicular pathway of amino acid delivery into endolysosomes, mediated by the actin cytoskeleton. Macropinocytosis delivered small, fluorescent fluid-phase solutes into endolysosomes sufficiently fast to explain growth factor–mediated signaling by amino acids. Therefore, the amino acid–laden macropinosome is an essential and discrete unit of growth factor receptor signaling to mTORC1
Sei Yoshida, Regina Pacitto, Yao Yao, Ken Inoki, Joel A. Swanson; Growth factor signaling to mTORC1 by amino acid–laden macropinosomes. J Cell Biol 12 October 2015; 211 (1): 159–172. https://doi.org/10.1083/jcb.201504097