These data were produced in the scope of research into understanding the application of zircon (U-Th)/He thermochronometric data derived from rocks with complex radiation damage distributions to the extraction of long-term (>1 Gyr) thermal histories of the Earth's upper crust. The samples used in this study were collected from the Front Range in Colorado, USA. The low-temperature (apatite and zircon (U-Th)/He) thermochronometric ages presented in this data set are sensitive to near-surface temperatures (~80C and 180C, respectively) and record the progressive exhumation of the rock mass from which the samples were collected towards the Earth's surface. These thermochronometric ages, and the differences between them, provide insight into the deep-time (~1000 Ma - 100 Ma) thermal history of the Colorado Front Range.