Index Catalog // Deep Blue Data

Need language around using Deep Blue Data as a repository for your NIH data sharing plan? See Data Sharing Boilerplate .

Start Over

Filtering by: Creator Kinsky, Nathaniel R Keyword Memory Consolidation

Data in support of the study "Erasable Hippocampal Neural Signatures Predict Memory Discrimination"

Creator:

Kinsky, Nathaniel R

Description:

This research investigated how blocking protein synthesis with anisomycin disrupted hippocampal neural dynamics underlying memory consolidation. We tracked neural activity using calcium before (2 days), during, and after (1, 2, and 7 days after) memory formation and consolidation using calcium imaging. We blocked memory consolidation in a subset of mice via systemic injections of the protein synthesis inhibitor anisomycin following fear conditioning. We examined place field remapping and stability, the formation of freeze-predictive hippocampal ensemble activity, and analyzed how blocking memory consolidation influenced these two phenomena.

Keyword:

Hippocampus, Memory Consolidation, Calcium imaging, and Electrophysiology

Citation to related publication:

Erasable Hippocampal Neural Signatures Predict Memory Discrimination. Kinsky, N.R.; Orlin, D.O.; Ruesch, E. A.; Kim, B.; Coello, S.; Diba, K; Ramirez, S., Cell Reports, in press.

Discipline:

Science