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Filtering by: Creator Lietzke, Anne C Discipline Engineering

Dataset for publication titled "Exendin-4 enhances insulin-positive phenotype of human pluripotent stem cell-derived beta cells during transplantation"

Creator:

Crumley, Kelly M, Bealer, Elizabeth J, Lietzke, Anne C, Soleimanpour, Scott A, and Shea, Lonnie D

Description:

The research described here includes a combination of in vivo animal studies and in vitro cell studies. The animal studies were conducted in NSG mice purchased from Jackson Laboratories and involve implantation of a cell-laden scaffold, animal monitoring, and scaffold explantation. After explantation, scaffolds could be analyzed using PCR or staining. The in vitro cell studies involved administration of Exendin-4 during differentiation of hPSC-derived beta cells and had endpoints such as PCR, flow cytometry, and staining.

Citation to related publication:

Crumbley, Bealer, Lietzke, Soleimanpour, Shea. Exendin-4 enhances insulin-positive phenotype of human pluripotent stem cell-derived beta cells during transplantation. In preparation.

Discipline:

Engineering