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Filtering by: Keyword cytochrome P450 ligands Discipline Health Sciences

Azole Library Description and Binding Parameters for CYP2A6, CYP2D6, and CYP8B1

Creator:

Frydendall, Elyse K and Scott, Emily E

Description:

The table herein consists of library compound names, vendors, catalog numbers, CAS numbers, molecular weights, PUBCHEM ID, cLogP, rotatable bonds, total polar surface area, IUPAC name, SMILES strings, notes on stability and absorbance limits, as well as Kd and ∆Amax values for CYP2A6, CYP2D6, and CYP8B1.

Keyword:

cytochrome P450 enzyme, high throughput screen, and cytochrome P450 ligands

Citation to related publication:

Frydendall, E.K. and E. E. Scott (2024). "Development of a high throughput cytochrome P450-ligand binding assay." J Biol Chem: 107799.

Discipline:

Health Sciences