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- Creator:
- Srivastava, Arnav, Kaufman, Samuel R., Liu, Xiu, Maganty, Avinash, Shay, Addison, Oerline, Mary, Dall, Christopher, Faraj, Kassem S., Guro, Paula, Hill, Dawson, Nguyen, Thuy, Herrel, Lindsey A., Hollenbeck, Brent K., and Shahinian, Vahakn B.
- Description:
- The STATA code in this deposit is the analytic code associated with the Cancer Medicine manuscript titled "Spillover Effects of Medicare Advantage on Traditional Medicare Beneficiaries With Prostate Cancer". About 51% of Medicare beneficiaries now select Medicare Advantage (MA) managed care plans. Unlike Traditional Medicare's fee-for-service structure, the capitated payment system of MA incentivizes constrained healthcare spending and utilization. MA's mechanisms to constrain spending and utilization may impact Traditional Medicare beneficiaries with prostate cancer through “spillover” effects on physician behavior. We therefore investigated whether the potentially constraining influences of MA on Traditional Medicare might affect prostate cancer testing and treatment patterns and impact quality of care.
- Keyword:
- active surveillance, financial incentives, Medicare, Medicare Advantage, and prostate cancer
- Citation to related publication:
- Srivastava, A., Kaufman, S.R., Liu, X., Maganty, A., Shay, A., Oerline, M., Dall, C., Faraj, K.S., Guro, P., Hill, D., Nguyen, T., Herrel, L.A., Hollenbeck, B.K. and Shahinian, V.B. (2025), Spillover Effects of Medicare Advantage on Traditional Medicare Beneficiaries With Prostate Cancer. Cancer Med, 14: e70796. https://doi.org/10.1002/cam4.70796
- Discipline:
- Health Sciences
-
- Creator:
- Whallon, Robert and Miracle, Preston T.
- Description:
- The data provided here are from the excavations made from 1986-1987 at the archaeological site of Badanj, in what was then the country of Yugoslavia, now Bosnia-Herzegovina. These excavations were supported by the Yugoslav-United States Joint Fund for Scientific and Technological Cooperation, administered in the U.S. by the National Science Foundation, Division of International Programs as grant INT-8605662, "Paleolithic and Mesolithic Investigation of the Adriatic-Mediterranean Region in Bosnia and Herzegovina," the University of Michigan, Horace H. Rackham School of Graduate Studies, Faculty Grant Program to Augment International Partnerships, the University of Michigan Museum of Anthropology, and the University of Michigan-Ann Arbor, Office of the Vice-President for Research.
- Keyword:
- archaeology, Paleolithic, Epigravettian, Yugoslavia, and Balkans
- Citation to related publication:
- Robert Whallon 1989. The paleolithic site of Badanj: recent excavations and results of analysis. Glasnik Zemaljskog Muzeja (Ser. A) NS 44:7-20., Preston Miracle and Derek Sturdy 1991. Chamois and the karst of Herzegovina. Journal of Archaeological Science 18:89-108., Preston T. Miracle and C. J. O'Brien 1998. Seasonality of resource use and site occupation at Badanj, Bosnia-Herzegovina: subsistence stress in an increasingly seasonal environment? In Seasonality and Sedentism: Archaeological Perspectives from Old and New World Sites, edited by T. Rocek and O. Bar-Yosef, pp. 41-74, Peabody Museum Bulletin 6. Peabody Museum of Archaeology and Ethnology, Harvard University, Cambridge, MA., Robert Whallon 1999. The lithic tool assemblages at Badanj within their regional context. In The Palaeolithic Archaeology of Greece and Adjacent Areas: Proceedings of the ICOPAG Conference, Ioannina. British School at Athens, Studies 3, edited by G. N. Bailey, E. Adam, E. Panagopoulou, C. Perles and K. Zachos, pp. 330–342. British School at Athens, London., Robert Whallon 2007. Spatial distributions and activities in Epigravettian level 6 at the site of Badanj, Bosnia and Herzegovina. Glasnik Srpskog Arheoloskog Drustva 23:9-26., and Robert Whallon 2025. Badanj: Epipaleolithic Excavations in Herzegovina, 1986-1987. Memoirs of the Museum of Anthropology, University of Michigan, Number 67, Ann Arbor, MI.
- Discipline:
- Social Sciences
-
- Creator:
- Bol, Ageeth A., Schulpen, Jeff J. P. M., Basuvalingam, Saravana, and Verheijen, Marcel A.
- Description:
- 3D nanostructures are a vital part of various applications envisaged for two-dimensional transition metal dichalcogenides (2D TMDs), such as nanoelectronics and catalysis. However, achieving conformal deposition of 2D TMD films on 3D nanostructures is challenging due to the requirement for bending the basal planes of the 2D TMDs. Here, the limits of conformality of 2D WS2 deposited by atomic layer deposition on SiO2 3D nanostructures are investigated through cross-sectional transmission electron microscopy imaging. A minimum radius of curvature of 4 nm is identified above which basal plane conformality is almost always observed, while for smaller radii conformality is only observed in approximately half of the cases. We show that the observed tipping point agrees with the balance between the adhesion and stiffness forces, which allows for the estimation of the critical radius of curvature for other 2D TMDs and substrates. These results provide guidelines for the design of 3D nanostructured devices and substrates on which conformality of 2D materials is desired.
- Keyword:
- Atomic Layer Deposition, WS2, and Conformality
- Citation to related publication:
- Jeff J. P. M. Schulpen, Saravana B. Basuvalingam, Marcel A. Verheijen, b and Ageeth A. Bol, Nanoscale, 2025
- Discipline:
- Science
-
- Creator:
- Dumlao, James M. Zumel and Teplitskiy, Misha
- Description:
- The data sources and methods used to process the raw data are described in the paper "The Role of Geographical Diversity of Peer Reviewers on the Diversity of Successful Authors" under revision at PNAS and the associated Supporting Information. A preprint for an earlier version of this paper is available here: https://osf.io/preprints/socarxiv/754e3_v3. These data are anonymized (see Methodology here for details). Consequently, running the same code on these data vs. the data in the paper does not yield *identical* results but qualitatively similar ones.
- Keyword:
- peer review, anonymization, geographic diversity, homophily, fairness, and bias
- Citation to related publication:
- J. M. Z. Dumlao, M. Teplitskiy, Proceedings of the National Academy of Sciences, forthcoming. and Zumel Dumlao, J. M. and M. Teplitskiy. 2025. “Lack of peer reviewer diversity advantages scientists from wealthier countries”. Retrieved (osf.io/preprints/socarxiv/754e3_v3).
- Discipline:
- Social Sciences and Science
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- Creator:
- Murguia, Amaya, Swanson, Scott D., Scheven, Ulrich, Jacobson, Andrea, Nielsen, Jon-Fredrik, Fessler, Jeffrey A., and Seraji-Bozorgzad, Navid
- Description:
- Validation of quantitative MRI (qMRI) parameters with histology is often done with ex vivo fixed tissue samples. Freezing is another common form of tissue preservation, but the effects of freezing and thawing tissue on myelin-sensitive qMRI parameters and their correlation with histology require further analysis. To study the effects of freezing vs. fixing tissue on myelin-sensitive parameters, we conducted myelin water imaging, off-resonance RF saturation magnetization transfer (MT), and selective inversion recovery MT MRI experiments on 14 fresh, thawed, and fixed sheep brain tissue samples to calculate various surrogate measures of myelin content. These measures were compared with luxol fast blue (LFB) histological stain results. 14 sheep brain tissue samples were scanned fresh. Half were frozen and subsequently thawed and scanned again. The second half were fixed and scanned again. Then all samples were fixed and sent for histological processing. This folder contains the MR and histology images collected for this study. All data are stored as mat files. The top level folder sheep_data_paper has subfolders: fresh_thawed: holds the data for the samples scanned fresh and thawed (S1-S7) fresh_fixed: holds the data for the samples scanned fresh and fresh_fixed (S8-S14) Each structure variable (data.mat) holds data for a specific sample and a specific tissue preparation (fresh, thawed, or fixed). The data variable has the following fields: gre: gradient echo scan data (128 x 128 x 5) fse: fast spin echo scan data (256 x 256 x 5) mese: multi-echo spin echo scan data for MWF mapping (128 x 128 x 5 x 104) b0data: gradient echo scan data for B0 mapping (128 x 128 x 5 x 4) b1data: EPI scan data for B1 mapping (32 x 32 x 5 x 9) t1data: EPI inversion recovery data for T1 mapping (64 x 64 x 5 x 21) mtdata: gradient echo data for quantitative MT analysis (128 x 128 x 4 x nf) hist: Luxol fast blue stain / Cresyl violet counterstain (LFB) histology image
- Keyword:
- myelin, magnetic resonance imaging, histology, quantitative MRI, ex vivo tissue, myelin water imaging, magnetization transfer, and luxol fast blue
- Citation to related publication:
- Murguia, A., Swanson, S. D., Scheven, U., Jacobson, A., Nielsen, J. F., Fessler, J. A., & Seraji-Bozorgzad, N. (2025). Impact of Tissue Sample Preparation Methods on Myelin-Sensitive Quantitative MR Imaging. bioRxiv, 2025-05.
- Discipline:
- Health Sciences and Engineering
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- Creator:
- Howard, Cecilia M., Sheldon, Nathan D., Loveall, Zachary, Keating, Katarina A., Hong, Jungpyo, Smith, Selena Y., and Passey, Benjamin H.
- Description:
- This study uses an array of stratigraphic, morphological, and geochemical tools to investigate lateral and temporal variability in environmental records preserved by microbialites during a global hothouse environment. It also inverts tools for reconstructing environmental conditions to elucidate ancient microbial processes. Key Points: - The Green River Basin, WY, USA preserves lacustrine microbialites deposited during the Early Eocene Climatic Optimum, a period of high CO2 and temperatures - Morphological and geochemical analyses of these microbialites preserve variable local, regional, and global environmental conditions - Measurements of environmental conditions can be inverted to understand ancient microbial processes, which could be used to inform modeling of microbial influences on carbon cycling and Abstract: The Green River Basin, WY, USA, contains extensive lacustrine microbialite beds that formed during the hothouse Early Eocene Climatic Optimum (53–49 Ma). The records of biological, chemical, and physical processes preserved in these microbialites can inform our understanding of terrestrial conditions in this warm climate, but separating the competing signals of local, regional and global changes is difficult. Studies focusing on individual localities may miss spatial drivers of differences in microbialites. In this study, we used stratigraphic, morphological, and geochemical techniques to study microbialites deposited in the Green River Basin across three million years spanning the peak of the EECO, including samples from two beds covering 13–25 km of lateral extent. These samples cover a broad set of lake conditions as well as local differences such as spring deposits. We found that these microbialites preserved a mixture of conditions such as global hothouse temperatures, regional shifts in lake level, and local variability from sediment and water sources. Morphological and elemental variability were driven primarily by local and regional conditions such as stream, spring, and clastic inputs and water depth. Isotopic data preserved these local and regional changes as well as evidence of global hothouse conditions. Comparison of past [CO2] estimates to reconstructions using organic and inorganic carbon isotopes with clumped isotope-derived temperatures provides evidence for low to moderate microbial growth rates in these microbialite building communities, demonstrating that environmental tools can be inverted to better understand ancient microbial processes. A diverse toolkit was necessary to isolate the individual controls on microbialite records, and comparing across both space and time enabled us to identify local drivers that lead to significant differences from the expected regional signal.
- Keyword:
- Geosciences, Paleoclimate, Microbialite, Stromatolite, Eocene, Paleolake, and Green River Basin
- Discipline:
- Science
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- Creator:
- Howard, Cecilia M., Velazquez, Diana, Rico, Kathryn I., and Sheldon, Nathan D.
- Description:
- This study combines a field survey time series with analysis of remotely and locally sensed environmental and climate data. Field survey data consists of sediment chemistry from hand-push cores, and includes %Corg, %N, δ13Corg, Corg:N, collection month and year, and depth in sediment. Climate and environmental data for the region around Middle Island Sinkhole was pulled from publicly available NOAA databases (ERDDAP, National Data Buoy Center, NWS) for as much of the same time period as the sediment data as was available. These data included general weather information from the NDBC and NWS (air temperature, wind speed, wind direction, gust speed, monthly precipitation totals), as well as satellite-derived environmental data from a 0.25° area centered on MIS (ice cover, lake surface temperature, CDOM, DOC, Chlorophyll, suspended minerals). Data were processed to monthly and annual averages as described below in order to compare to sinkhole sediment chemistry. Abstract: Records of recent past climate provide an essential window into understanding how changing climate influences environments and ecosystems such as lakes. Sediment carbon and nitrogen chemistry can offer insight into productivity and biochemistry, and anoxic sediments can often preserve short-term changes in these signals. We found that seasonal and annual changes in local ice season, chlorophyll, and precipitation influenced the amount and isotopic composition of carbon reaching the sediments of Middle Island Sinkhole, an anoxic sinkhole in Lake Huron. Carbon and nitrogen signals reflected the year or season of sample collection in sediments as deep as 12 cm. Our findings demonstrate that declining ice cover in this part of the Great Lakes is leading to increased export of organic carbon into sediments, but that in situ sediment processes may make teasing out short-term changes from sediment cores difficult even in an anoxic setting.
- Keyword:
- Carbon burial, Great Lakes, Ice cover, Sediment carbon, Sediment nitrogen, Anoxia, and Geosciences
- Discipline:
- Science
-
- Creator:
- Howard, Cecilia M. and Sheldon, Nathan D.
- Description:
- This study uses a compilation of microbialite occurrences in the Archean and Paleoproterozoic from the literature to investigate how depositional environment changed across environmental shifts such as the Great Oxidation Event and the Huronian Glaciations. Key Points: - We compiled microbialite occurrences from the Archean and Paleoproterozoic with broad depositional environment information, which has not previously been incorporated in larger compilations of occurrences. - Tidal and other terrestrially-influenced settings comprise the majority of the early microbialite record, even across major environmental shifts and Abstract: Changes in microbialite abundance during the Archean and Paleoproterozoic have been attributed to a variety of environmental and biological factors. Past work looking at large-scale patterns of microbialite abundance generally assumes shallow marine deposition rather than incorporating specific settings, however, there is significant variance in conditions that might impact microbialite formation and preservation between marine, tidal, and terrestrial environments. We compiled microbialite occurrences from the Archean and Paleoproterozoic with integrated depositional environment information in order to assess how microbialite development and preservation changed across different settings. Microbially induced sedimentary structures formed a significant part of the record, but their identification primarily in conjunction with stromatolites rather than independently suggests that they may be undercounted. Broad trends in abundance were similar to previous compilations, but critically, we found that the majority of microbialites from this period formed in tidal environments. The proportion of terrestrially-influenced (including tidal) microbialites increased during periods of craton development in the Neoarchean and mid-Paleoproterozoic, with increases in marine microbialite abundance trailing. Tidal microbialite abundance also recovered more quickly than marine abundance following the Great Oxidation Event and Huronian Glaciations.
- Keyword:
- Microbialite, Stromatolite, Archean, Paleoproterozoic, Geosciences, and Tidal
- Discipline:
- Science
-
- Creator:
- Zetterberg, Daniel S., Huang, Xianglei, Hörner, Johannes, Voigt, Aiko, and Chen, Xiuhong
- Description:
- The data and code stored in this repository present the results of the paper "Instantaneous radiative effect of surface long wave spectral emissivity in a Snowball Earth simulation." In this paper, we calculate the instantaneous radiative effects of surface spectral emissivity for a Snowball Earth simulation, and find that including surface spectral emissivity has a moderate effect on the radiation budget. For clear-sky conditions, using ice or snow spectral emissivity can decrease outgoing long wave radiation by 2.9 or 1.0 W/m^2, respectively, globally averaged. This large effect could impact the simulated climate state of a Snowball Earth and potentially strengthen the Jormungand mechanism. Additionally, the large difference between ice and snow highlights the importance of precipitation processes in Snowball modeling. , This repository contains the results of the calculations and the data and code needed to recreate the manuscript figures. It contains atmospheric conditions from the simulations run by JH and AV that were processed by DSZ. It also contains emissivity datasets that were compiled by Huang et al. 2016 ("A global data set of surface spectral emissivity for GCM and NWP use"). MODTRAN calculations of the outgoing longwave radiation were processed by DSZ, XLH, and XC. The results of the study are contained in netcdf files. The README file offers a description, and the Jupyter notebook demonstrates how to access, use, and plot the calculations. , and ***Changes on 10 June, 2025*** New data files contain the outgoing longwave radiation from MODTRAN calculations, but with multiple scattering enabled in MODTRAN. The result is that downward atmospheric radiation can reflect off the surface back to the top of the atmosphere. The result is that the effect of surface emissivity is slightly decreased, though the conclusions and discussion remain unchanged. Additionally, Xiuhong Chen was added as an author, as her expertise in MODTRAN aided in resolving this issue. Data for a plot of a sample emission spectrum was also added, as this was used in the revised manuscript. Key points were updated to match those in the related article.
- Keyword:
- Spectral surface emissivity, Snowball Earth, paleoclimate modeling
- Citation to related publication:
- Zetterberg, D.S., Huang, X.L., Hörner, J., & Voigt, A. Instantaneous radiative effect of surface long wave spectral emissivity in a Snowball Earth simulation. Submitted to Journal of Geophysical Research: Atmospheres, February 2025
- Discipline:
- Science
-
- Creator:
- Colón-Rodríguez, Stephanie, Liemohn, Michael, Raines, Jim, and Lepri, Susan T.
- Description:
- During its trajectory, Wind spent a significant amount of time in the magnetotail, where its SupraThermal Ion Composition Spectrometer (STICS) measured the mass and mass per charge of protons, alpha particles, and heavy ions with an energy/charge ratio up to 226 keV/e. Although STICS originally aimed to measure the abundance of these ion species in the solar wind, its measurements within the magnetosphere from 1995 to 2002 help us identify preferential entry between the different solar wind ion species. This study statistically analyzes how the ratio between solar wind heavy ions and alpha particles (Heavies Solar Wind / He2+) varies for different upstream conditions and locations within the magnetosphere: northward vs. southward Interplanetary Magnetic Field (IMF), low vs. high solar wind density (Nsw), low vs. high solar wind dynamic pressure (PDyn), slow vs. fast solar wind (Vsw), and dawn vs. dusk. Our results indicate that the HeaviesSolar Wind enter the magnetosphere more efficiently than He2+ during northward IMF and that the Heavies Solar Wind / He2+ ratios decrease during high PDyn. In addition, the Heavies Solar Wind / He2+ ratios exhibit a dawn-dusk asymmetry, highly skewed towards the dawn side for all upstream cases likely due to charge-exchange processes.
- Keyword:
- Magnetosphere, Wind STICS, Solar wind heavy ions, Alpha particles, and dawn-dusk asymmetry
- Citation to related publication:
- Colón-Rodríguez, S., Liemohn, M. W., Raines, J. M, & Lepri, S.T. (2024). Solar wind heavy ions and alpha particles within Earth’s magnetosphere and their variability with upstream conditions. Journal of Geophysical Research Space Physics. In preparation.
- Discipline:
- Science