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- Creator:
- Velez Rosado, Kevin I.
- Description:
- This collection includes computed tomography (CT) scans of cranial and post-cranial remains of Dolichochampsa minima (Crocodylia) from the Cretaceous of Bolivia. The specimen was collected by the auspice of Princeton University. The specimen is currently housed at the University of Michigan Museum of Paleontology.
- Keyword:
- Paleontology, Bolivia, Crocodylia, Cretaceous
- Citation to related publication:
- Kevin I. Vélez-Rosado, Olga I. Zalles-Grebetskaya, Jeffrey A. Wilson Mantilla, Blaire Schoene, Adam Maloof, and Bolton, Howes. 2025. New material of Dolichochampsa minima (Archosauria: Crocodylia) from the Cretaceous–Paleogene El Molino Formation of Bolivia sheds light on the early evolution of Gavialinae. Unpublished manuscript.
- Discipline:
- Science
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- Creator:
- Best, T. Kevin, Seelhoff, C. Andrew, Wensman, Jeffrey, and Gregg, Robert D.
- Description:
- The dataset was collected to assess the clinical benefits of the latest generation Össur Power Knee with and without phase-based control compared to traditional passive microprocessor-controlled knees. The study included seven above-knee amputee participants and examined performance across a series of sit/stand and walking experiments. Data captured includes event logs, processed inverse kinematics and dynamics data, scaled OpenSim skeletons for each session, and raw motion capture and force plate data for various test conditions (HKIC, OSSR, PRES). All data is text-based and can be viewed in any compatible text editor. Data can be visualized in OpenSim. The dataset is organized by subject and test condition. Each folder includes a scaled subject OpenSim skeleton (*_skeleton.osim), a marker file for a range of motion trial (*_range_of_motion.trc), and three test folders each containing: Event Logs (*.event_log.csv): Time-stamped records of experimental events. Inverse Kinematics Data (*_IK.mot): Joint angle trajectories. Inverse Dynamics Data (*_ID.mot): Joint moment trajectories. Raw Marker Data (*_markers.csv): 3D coordinates of motion capture markers. Ground Reaction Force Data (*_GRF.mot): Force plate measurements of ground reactions during movement tasks.
- Keyword:
- Robotic Prostheses, Transfemoral Amputees, and Prosthesis Control
- Citation to related publication:
- T. Kevin Best, C. Andrew Seelhoff, Jeffrey Wensman, Robert D. Gregg, "The Össur Power Knee with Phase-Based Control Provides Clinical Benefits over Passive Microprocessor Knees," Submitted to the Journal of NeuroEngineering and Rehabilitation, 2025.
- Discipline:
- Engineering and Health Sciences
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- Creator:
- Lydick, Nathanial and Deng, Hui
- Description:
- The included python scripts and Jupyter notebook generate and analyze the data.
- Keyword:
- Molecular Polariton, Dimensional Dependence, Tavis-Cummings Model, Strong Coupling, and Disorder
- Citation to related publication:
- N. Lydick, J. Hu, and H. Deng, "Dimensional dependence of a molecular-polariton mode number," J. Opt. Soc. Am. B 41, C247-C253 (2024). https://doi.org/10.1364/JOSAB.524026
- Discipline:
- Science
-
- Creator:
- Nicholas, Benjamin and López-Fernández, Hernán
- Description:
- Understanding how continental assemblages have diversified can be difficult as they are products of extinction, biogeographic rearrangements, and changing environments over millions of years. Much of our knowledge of adaptive radiations stems from relatively recent, insular-like systems. However, increasing evidence supports the idea that adaptive radiations have a major role in hyper diverse continental radiations like Neotropical cichlids. This primarily riverine group has undergone adaptive diversification in many into ecologically, morphologically, and behaviorally complex lineages. Surprisingly, the macroevolutionary patterns of the entire pharyngeal jaw is relatively understudied in Neotropical cichlids. In this study we use µCT scans to characterize the entire pharyngeal system across Neotropical cichlids to test for signatures of adaptive radiation. We describe the morphological diversity of the upper and lower pharyngeal jaw, fit models of evolutionary divergence, and measure morphological disparity through time and among clades. Until now, studies of various axes of diversification in Cichlinae found a congruent signals an early bursts of divergence in multiple trait dimensions, however we find no evidence of an early burst in the pharyngeal jaws. We find evidence of highly specialized pharyngeal jaws establishing early in the continental radiation and also evidence of recent morphological divergence in the three major tribes of Cichlinae. Our results further highlight the necessity to study adaptively radiating lineages in multiple trait dimensions as some axes of diversification may be overlooked. and This dataset contains landmarked files of 204 landmarks for 95 species (one specimen per species) of Neotropical cichlids. Files are named "Genus_species.mrk.json". Landmark files can be read with the programming language R with the scripts found in the supplemental files of the cited paper, Nicholas and López-Fernandez 2024.
- Keyword:
- Landmarks, Cichlid, Pharyngeal Jaw, and Neotropics
- Citation to related publication:
- Benjamin Nicholas, Hernán López-Fernández, Analysis of the whole pharyngeal jaw adds nuance to the continental radiation of Neotropical cichlids, Evolutionary Journal of the Linnean Society, Volume 3, Issue 1, 2024, kzae038, https://doi.org/10.1093/evolinnean/kzae038
- Discipline:
- Science
-
- Creator:
- Soni, Shirsh Lata and Akhavan-Tafti, Mojtaba
- Description:
- The Sun Radio Interferometer Space Experiment (SunRISE) Ground Radio Lab (GRL) is a Science, Technology, Engineering, Arts, and Mathematics (STEAM) project aiming to engage and train the next generations of scholars. To achieve this, the project 1) recruited students to participate in the design, development, and testing of a simple antenna kit that were sent to high schools nationwide free of charge, 2) prepared online, self-paced training modules to educate students on topics including radio astronomy and space weather, and 3) recruited high schools to host antenna installations, participate in regular data collection and analysis campaigns, and engage in monthly webinars and Q&A sessions with space industry experts. and For more information about SunRISE GRL, visit https://sunrise.umich.edu/
- Keyword:
- Solar Radio Bursts, SunRISE Ground Radio Lab (GRL), and Dual Dipole Antenna
- Citation to related publication:
- Mojtaba Akhavan-Tafti, Shirsh Soni, Charles Higgins, et al. SunRISE Ground Radio Lab. Authorea. September 26, 2024. Preprint. 10.22541/au.172737940.04250524/v1
- Discipline:
- Science
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- Creator:
- Su, Xue, Zhang, Youxue, Liu, Yang, and Holder, Robert M.
- Description:
- Volcanic glass beads on the Moon have traditionally been thought to only record volatile loss during pyroclastic eruptions. However, recent discoveries have shown that lunar orange glass beads, representing primitive high-Ti basalts, experienced both outgassing and in-gassing of volatile elements such as Na, K, Cu, and S. In this work, we examine lunar green glass beads from sample 15421 and 15366, representing primitive very-low-Ti basalts, for the distribution of Na, K and Cu using EMP analyses and LA-ICP-MS mapping. It is found that all studied lunar green beads show increased Na, K and Cu concentrations near bead surfaces, indicative of in-gassing. A quantitative model is developed to simulate the concentration evolution of Na and Cu in individual green glass beads during eruption and cooling. The presence of similar in-gassing diffusion profiles of volatile elements in beads from different eruptions indicates a common behavior of lunar volcanic gas. In addition to volatile in-gassing, LA-ICP-MS mapping of Na and K in one green bead from sample 15366 shows features suggesting collision of melt droplets during the fire-fountain eruption, revealing more details in the dynamic aspects of lunar fire-fountain eruptions. Compared to orange glass beads, the varying boundary conditions of green glass beads during formation may suggest that their eruption plume evolved and dissipated more rapidly, potentially linked to changes in the global lunar atmosphere.
- Keyword:
- Moon, Lunar green glass beads, Diffusion, Outgassing and in-gassing, Moderately volatile elements, Cooling time scales, and Lunar pyroclastic beads
- Discipline:
- Science
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- Creator:
- Haynes, Laura M, Holding, Matthew L, DiGiovanni, Hannah L, Siemieniak, David, and Ginsburg, David
- Description:
- This data set contains FASTQ files of PAI-1 sequence variants that differentially inhibit different target proteases. The software needed to analyze these files can be found at https://github.com/hayneslm/PAI-1_and_divergent_proteases.
- Keyword:
- serpins, serine proteases, coevolution, deep mutational scanning, fibrinolysis, phage display, protein-protein interactions, sequence space, DNA sequencing
- Citation to related publication:
- Haynes LM, Holding ML, DiGiovanni H, Siemieniak D, Ginsburg D. High-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases. bioRxiv [Preprint]. 2024 Sep 20:2024.09.16.612699. doi: 10.1101/2024.09.16.612699. PMID: 39345533; PMCID: PMC11429915.
- Discipline:
- Science
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- Creator:
- Kinsky, Nathaniel R
- Description:
- This research investigated how blocking protein synthesis with anisomycin disrupted hippocampal neural dynamics underlying memory consolidation. We tracked neural activity using calcium before (2 days), during, and after (1, 2, and 7 days after) memory formation and consolidation using calcium imaging. We blocked memory consolidation in a subset of mice via systemic injections of the protein synthesis inhibitor anisomycin following fear conditioning. We examined place field remapping and stability, the formation of freeze-predictive hippocampal ensemble activity, and analyzed how blocking memory consolidation influenced these two phenomena.
- Keyword:
- Hippocampus, Memory Consolidation, Calcium imaging, and Electrophysiology
- Citation to related publication:
- Erasable Hippocampal Neural Signatures Predict Memory Discrimination. Kinsky, N.R.; Orlin, D.O.; Ruesch, E. A.; Kim, B.; Coello, S.; Diba, K; Ramirez, S., Cell Reports, in press.
- Discipline:
- Science
-
- Creator:
- Murray, Kendra E., Niemi, Nathan A., Clark, Marin K., and Siddoway, Christine
- Description:
- The Front Range of the Southern Rocky Mountains near Boulder, CO contains a rock record that spans nearly 1.7 billion years. Zircon U-Pb geochronology is an isotopically-based chronometer for measuring deep earth time. We apply this method to a series of small igneous intrusive bodies from the Front Range west of Boulder, CO. These instrusives are collectively known as the Colorado Mineral Belt (CMB) for the economic mineral deposits associated with the instrusives. Past geochronological methods have provided only rudimentary constraints on the geologic timing of emplacement of these bodies. We demonstrate the CMB magmatic activity in the Front Range occurred in two discrete pulses, one at ~67 Ma (million years ago) and one at ~47 Ma. Additional application of the same methodology to a sedimentary rock, the Neoproterozoic Tavakiav Quartzite, uses the zircon U-Pb ages as tracers to constrain the provenance and depositional age of this unique sand body.
- Keyword:
- zircon, Colorado, Front Range, geochronology, Tava, Colorado Mineral Belt, Eldorado stock, Bryan Mountain stock, Sugarloaf, Sunset stock, Bald Mountain, Caribou stock, North Fork, CMB, Front Range mineral belt, and Jamestown
- Citation to related publication:
- Murray, K. E., Niemi, N. A., & Clark, M. K. (2025). Evidence for the Neoproterozoic rifting of Rodinia in the Rocky Mountain Front Range. Tectonics, 44, e2023TC008216.
- Discipline:
- Science
-
- Creator:
- Morgan, Rachel K, Tapaswi, Anagha, and Colacino, Justin
- Description:
- SH-SY5Y cells were differentiated into neuron-like cells in the presence of continuous and environmentally relevant levels of lead (Pb). Cells were collected every three days (beginning on day 6 of the 18 day protocol) for the purposes of RNA extraction and subsequent sequencing.
- Keyword:
- Neurotoxicology, Chemical Exposure, Benchmark Dose, Transcriptomics
- Citation to related publication:
- Rachel K. Morgan, Anagha Tapaswi, Katelyn M. Polemi, Elizabeth C. Tolrud, Kelly M. Bakulski, Laurie K. Svoboda, Dana C. Dolinoy, Justin A. Colacino bioRxiv 2024.10.29.620844; doi: https://doi.org/10.1101/2024.10.29.620844
- Discipline:
- Health Sciences