Experimental & numerical investigations of ultra-high-speed dynamics of optically-induced droplet vaporization in soft materials

A. Abeid, Bachir; L. Fabiilli, Mario; Aliabouzar, Mitra; Estrada, Jon B.

Work Description

Title: Experimental & numerical investigations of ultra-high-speed dynamics of optically-induced droplet vaporization in soft materials Open Access Deposited

Attribute	Value
Methodology	Briefly, a single pulse is fired by two sequential triggering signals: the first triggers the laser flash lamp and the second fires the Q-switch. As the laser is deposited into a soft hydrogel sample containing phase-shift droplets, the event is illuminated from the back via a 640 nm monochromatic ultra-high-speed strobed diode laser and continuous quartz tungsten-halogen lamp (. The illumination laser is triggered by the high-speed camera sync-out signal. The laser beam/pulse was aligned to the back apparatus of a 20×/0.25 high-power microspot focusing objective using three reflective broadband dielectric mirrors , three short-pass dichroic mirrors, a beam-sampler lens, and a spatial light modulator (SLM). The collected images are processed using an in-house developed MATLAB image processing routine.
Description	Images of droplet dynamics during and after optical excitation experiments were recorded in the ultra-fast regime at 1 million frames per second (fps) while the low-speed, quasi-static evolution was carried at 1 fps. During both the inertial and quasi-static phases, we record 1–3 frames in the reference configuration prior to the arrival of the laser-pulse to distinguish the bubble from the background. Lastly, due to the complex physics of plasma formation and chemistry, forward simulations begin at the time when the bubble reaches its maximum expansion
Creator	A. Abeid, Bachir L. Fabiilli, Mario Aliabouzar, Mitra Estrada, Jon B.
Creator ORCID	https://orcid.org/0009-0009-0859-8434 https://orcid.org/0000-0002-4752-9812 https://orcid.org/0000-0002-7441-3479 https://orcid.org/0000-0003-1083-4597
Depositor	babeid@umich.edu
Contact information	jbestrad@umich.edu
Discipline	Science Engineering
Funding agency	National Institutes of Health (NIH) National Science Foundation (NSF) Other Funding Agency
Other Funding agency	startup funding from University of Michigan, Department of Mechanical Engineering (JBE)
ORSP grant number	R01HL139656, CMMI2232426
Keyword	optical droplet vaporization, cavitation, viscoelasticity, ultra-high-speed imaging, hydrogel, numerical modeling.
Citations to related material	Abeid, Bachir A, et al. (2024). Experimental and numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials
Resource type	Dataset
Last modified	10/14/2024
Published	10/14/2024
Language	English
DOI	https://doi.org/10.7302/yb8v-pp71
License	http://creativecommons.org/licenses/by-nc/4.0/

To Cite this Work:
A. Abeid, B., L. Fabiilli, M., Aliabouzar, M., Estrada, J. B. (2024). Experimental & numerical investigations of ultra-high-speed dynamics of optically-induced droplet vaporization in soft materials [Data set], University of Michigan - Deep Blue Data. https://doi.org/10.7302/yb8v-pp71

Relationships


This work is not a member of any user collections.

Files (Count: 5; Size: 5.83 GB)

Title	Original Upload	Last Modified	File Size	Access	Actions
Processed_Data.mat	2024-05-07	2024-05-14	4.9 MB	Open Access	View Details Download
AVI24_Fibrin.zip	2024-05-10	2024-05-10	1.71 GB	Open Access	View Details Download
AVI24_Gelatin.zip	2024-05-10	2024-05-10	1.86 GB	Open Access	View Details Download
AVI24_PA.zip	2024-05-10	2024-05-10	2.26 GB	Open Access	View Details Download
Readme.txt	2024-10-11	2024-10-11	5.42 KB	Open Access	View Details Download

Date: 11 October 2024

Dataset Title: Experimental & numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials

Dataset Creators: Bachir A. Abeid, Mario L. Fabiilli, Mitra Aliabouzar, Jon B. Estrada

Dataset Contact: Bachir A. Abeid babeid@umich.edu

Funding: NIH Grant R01HL139656 (MLF), startup funding from University of Michigan - Department of Mechanical Engineering (JBE),funding for experimental platform development from NSF grant CMMI2232426 (JBE)

Key Points:
- We examined effects such as droplet size and PFC core on bubble dynamics and material viscoelastic properties within three different hydrogels, each of different concentrations.
- Gelatin hydrogels reveal concentration-dependent impacts on bubble expansion and material elasticity.
- Embedding PFC droplets in gelatin increases internal pressure, resulting in higher equilibrium radius and continuous bubble growth during quasi-static evolution.
- Similar trends are observed in fibrin and polyacrylamide matrices, with differences in bubble behavior attributed to matrix properties and droplet presence.
- Droplet size exhibits minimal impact on bubble expansion during inertial dynamics but influences quasi-static evolution, with larger droplets leading to continuous growth beyond 60 seconds.
- The core composition of PFC droplets significantly affects bubble behavior, with higher boiling point droplets exhibiting higher maximum expansion and faster quasi-static dissolution rates.

Research Overview:
Perfluorocarbon (PFC) droplets represent a novel class of phase-shift contrast agent with a promise in applications in biomedical and bioengineering fields. PFC droplets undergo a fast liquid-gas transition upon exposure to acoustic or optical triggering,
offering a potential adaptable and versatile tool as contrast agent in diagnostics imaging and localized drug delivery vehicles in therapeutics systems. In this paper, we utilize advanced imaging techniques to investigate ultra-high-speed inertial dynamics and
rectified quasi-static (low-speed) diffusion evolution of optically induced PFC droplet vaporization. The study sheds light on the intricate interplay between droplet characteristics, matrix properties, and multi-timescale bubble dynamics, offering valuable insights into their behavior within biomimetic hydrogels.

Methodology:
The data are the output of the microcavitation experimental setup, which generates and records single, sub-millimeter laser-induced cavitation (LIC) bubble events at 1 million fps in soft hydrogels and materials using a combination of single 4 ns pulses of a user-adjustable,
frequencydoubled Q-switched 532 nm Nd:YAG laser (Continuum Minilite II, San Jose, CA), an ultra-high-speed imaging camera (HPV-X2; Shimadzu, Kyoto, Japan) and a low-speed imaging camera (FLIR).

Instrument and/or Software specifications: Videos where processed using Matlab R2023a

Files contained here:
Matlab file (.mat) include all processed experiments.

Three folders contain raw AVI videos.
The videos names end in time(HH_MM_SS). The prefixes are described below.

AVI24_Gelatin
- Geletin_05w_w : 05% Native Gelatin
- Geletin_10w_w : 10% Native Gelatin
- Geletin_15w_w : 15% Native Gelatin
- pfh_12_Gel_10w_w : 10% Gelatin with 12 um diameter PFH droplets
- pfo_12_Gel_10w_w : 10% Gelatin with 12 um diameter PF0 droplets
- pfp_3_Gel_10w_w : 10% Gelatin with 3 um diameter PFP droplets
- pfp_6_Gel_10w_w : 10% Gelatin with 6 um diameter PFP droplets
- pfp_Gelat_05w_w : 05% Gelatin with 12 um diameter PFP droplets
- pfp_Gelat_10w_w : 10% Gelatin with 12 um diameter PFP droplets
- pfp_Gelat_15w_w : 15% Gelatin with 12 um diameter PFP droplets

AVI24_Fibrin
- Fib_02_10X : 0.2% Native Fibrin
- Fib_02_10X_pfp : 0.2% Fibrin with 6 um diameter PFP droplets
- Fib_01_10X : 1% Native Fibrin
- Fib_01_10X_pfp : 1% Fibrin with 6 um diameter PFP droplets
- Fib_04_10X : 4% Native Fibrin
- Fib_04_10X_pfp : 4% Fibrin with 6 um diameter PFP droplets

AVI24_PA
PA_B_S1 : 3/0.1 Native Polyacrylamide (Acry/Bis %)
PA_B_pfp_S1 : 3/0.1 Polyacrylamide (Acry/Bis %) with 6 um diameter PFP droplets
PA_D_S1 : 5/0.15 Native Polyacrylamide (Acry/Bis %)
PA_D_pfp_S1 : 5/0.15 Polyacrylamide (Acry/Bis %) with 6 um diameter PFP droplets
PA_E_S1 : 5/0.3 Native Polyacrylamide (Acry/Bis %)
PA_E_pfp_S1 : 5/0.3 Polyacrylamide (Acry/Bis %) with 6 um diameter PFP droplets
PA_F_S1 : 8/0.26 Native Polyacrylamide (Acry/Bis %)
PA_F_pfp_S1 : 8/0.26 Polyacrylamide (Acry/Bis %) with 6 um diameter PFP droplets

Each files has the following variables:

Roft = Bubble radius during inertial dynamics in (m)
t = time during inertial dynamics in (s)
t_norm = Normalized time
R_norm = Normalized Radius
t0 = maximum expansion time (s)
R0 = Maximum expansion (m)
Req = equilibrium radius during inertial dynamics in (m)
Related publication(s):
Abeid, Bachir A, et al. (2024). Experimental and numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials  

Use and Access:
This data set is made available under a Creative Commons Public Domain license (CC0 1.0).

To Cite Data:
Bachir A. Abeid, Mario L. Fabiilli, Mitra Aliabouzar, Jon B. Estrada. (2024). Experimental and numerical investigations of ultra-high-speed dynamics of optically induced droplet cavitation in soft materials [Data set]. University of Michigan - Deep Blue. https://doi.org/10.7302/yb8v-pp71

Update Provenance Log Entries

Download All Files (To download individual files, select them in the “Files” panel above)

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.