Characterization of a High‐Spin Non‐Heme {FeNO} 8 Complex: Implications for the Reactivity of Iron Nitroxyl Species in Biology
dc.contributor.author | Speelman, Amy L. | en_US |
dc.contributor.author | Lehnert, Nicolai | en_US |
dc.date.accessioned | 2013-12-04T18:58:10Z | |
dc.date.available | 2015-01-05T13:54:43Z | en_US |
dc.date.issued | 2013-11-18 | en_US |
dc.identifier.citation | Speelman, Amy L.; Lehnert, Nicolai (2013). "Characterization of a High‐Spin Non‐Heme {FeNO} 8 Complex: Implications for the Reactivity of Iron Nitroxyl Species in Biology ." Angewandte Chemie International Edition 52(47): 12283-12287. | en_US |
dc.identifier.issn | 1433-7851 | en_US |
dc.identifier.issn | 1521-3773 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/101872 | |
dc.publisher | WILEY‐VCH Verlag | en_US |
dc.subject.other | Reduction | en_US |
dc.subject.other | Bioinorganic Chemistry | en_US |
dc.subject.other | Nitrogen Oxides | en_US |
dc.subject.other | Nitroxyl Complexes | en_US |
dc.subject.other | Non‐Heme Iron | en_US |
dc.title | Characterization of a High‐Spin Non‐Heme {FeNO} 8 Complex: Implications for the Reactivity of Iron Nitroxyl Species in Biology | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109 (USA) | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/101872/1/12283_ftp.pdf | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/101872/2/anie_201305291_sm_miscellaneous_information.pdf | |
dc.identifier.doi | 10.1002/anie.201305291 | en_US |
dc.identifier.source | Angewandte Chemie International Edition | en_US |
dc.identifier.citedreference | Experimental details for the acquisition of crystal data and structure refinement can be found in the Supporting Information. CCDC 945365 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif. | en_US |
dc.identifier.citedreference | J. H. Enemark, R. D. Feltham, Coord. Chem. Rev. 1974, 13, 339 – 406. | en_US |
dc.identifier.citedreference | R. Lin, P. J. Farmer, J. Am. Chem. Soc. 2000, 122, 2393 – 2394. | en_US |
dc.identifier.citedreference | T. C. Berto, A. L. Speelman, S. Zheng, N. Lehnert, Coord. Chem. Rev. 2013, 257, 244 – 259. | en_US |
dc.identifier.citedreference | J. D. M. Kurtz, Jr., Dalton Trans. 2007, 4115 – 4121. | en_US |
dc.identifier.citedreference | en_US | |
dc.identifier.citedreference | D. Lancon, K. M. Kadish, J. Am. Chem. Soc. 1983, 105, 5610 – 5617; | en_US |
dc.identifier.citedreference | I. K. Choi, Y. Liu, D. Feng, K. J. Paeng, M. D. Ryan, Inorg. Chem. 1991, 30, 1832 – 1839; | en_US |
dc.identifier.citedreference | J. Pellegrino, S. E. Bari, D. E. Bikiel, F. Doctorovich, J. Am. Chem. Soc. 2010, 132, 989 – 995; | en_US |
dc.identifier.citedreference | L. E. Goodrich, S. Roy, E. E. Alp, J. Zhao, M. Y. Hu, N. Lehnert, Inorg. Chem. 2013, 52, 7766 – 7780. | en_US |
dc.identifier.citedreference | A. K. Patra, K. S. Dube, B. C. Sanders, G. C. Papaefthymiou, J. Conradie, A. Ghosh, T. C. Harrop, Chem. Sci. 2012, 3, 364 – 369. | en_US |
dc.identifier.citedreference | R. García‐Serres, C. A. Grapperhaus, E. Bothe, E. Bill, T. Weyhermüller, F. Neese, K. Wieghardt, J. Am. Chem. Soc. 2004, 126, 5138 – 5153. | en_US |
dc.identifier.citedreference | K. M. Miranda, Coord. Chem. Rev. 2005, 249, 433 – 455. | en_US |
dc.identifier.citedreference | en_US | |
dc.identifier.citedreference | J. England, E. R. Farquhar, Y. Guo, M. A. Cranswick, K. Ray, E. Münck, L. Que, Inorg. Chem. 2011, 50, 2885 – 2896; | en_US |
dc.identifier.citedreference | J. England, Y. Guo, E. R. Farquhar, V. G. Young, Jr., E. Münck, L. Que, Jr., J. Am. Chem. Soc. 2010, 132, 8635 – 8644; | en_US |
dc.identifier.citedreference | H. Wittmann, V. Raab, A. Schorm, J. Plackmeyer, J. Sundermeyer, Eur. J. Inorg. Chem. 2001, 1937 – 1948. | en_US |
dc.identifier.citedreference | As noted previously, [10a] the large τ value (>1) presumably arises from the 0.364 Å displacement of the Fe center from the mean plane defined by the equatorial nitrogen atoms. | en_US |
dc.identifier.citedreference | M. Ray, A. P. Golombek, M. P. Hendrich, G. P. A. Yap, L. M. Liable‐Sands, A. L. Rheingold, A. S. Borovik, Inorg. Chem. 1999, 38, 3110 – 3115. | en_US |
dc.identifier.citedreference | T. C. Berto, M. B. Hoffman, Y. Murata, K. B. Landenberger, E. E. Alp, J. Zhao, N. Lehnert, J. Am. Chem. Soc. 2011, 133, 16714 – 16717. | en_US |
dc.identifier.citedreference | K. Pohl, K. Wieghardt, B. Nuber, J. Weiss, J. Chem. Soc. Dalton Trans. 1987, 187 – 192. | en_US |
dc.identifier.citedreference | Z. J. Tonzetich, F. Héroguel, L. H. Do, S. J. Lippard, Inorg. Chem. 2011, 50, 1570 – 1579. | en_US |
dc.identifier.citedreference | The parent complex [Fe(TMG 3 tren)(CH 3 CN)] 2+ shows only an irreversible reductive event at approximately −2.5 V versus ferrocene, [10c] which indicates that the reduction of 1 is not ligand‐based. This conclusion is supported by DFT calculations, which show only a small change in spin density on the ligand in 2 as compared to 1 (see Table S3 in the Supporting Information). Rather, the splitting in the ligand bands is indicative of changes in the covalency of the iron–TMG 3 tren unit. | en_US |
dc.identifier.citedreference | C. A. Brown, M. A. Pavlosky, T. E. Westre, Y. Zhang, B. Hedman, K. O. Hodgson, E. I. Solomon, J. Am. Chem. Soc. 1995, 117, 715 – 732. | en_US |
dc.identifier.citedreference | N. Lehnert, V. K. K. Praneeth, F. Paulat, J. Comput. Chem. 2006, 27, 1338 – 1351. | en_US |
dc.identifier.citedreference | No experimental p K a values for biological {FeHNO} 8 ‐type complexes have been reported; however, DFT calculations suggest that 2 is less basic than the corresponding low‐spin (heme) complexes (see the Supporting Information). | en_US |
dc.identifier.citedreference | S. Ye, J. C. Price, E. W. Barr, M. T. Green, J. M. Bollinger, C. Krebs, F. Neese, J. Am. Chem. Soc. 2010, 132, 4739 – 4751. | en_US |
dc.identifier.citedreference | S. Zheng, T. C. Berto, E. W. Dahl, M. B. Hoffman, A. L. Speelman, N. Lehnert, J. Am. Chem. Soc. 2013, 135, 4902 – 4905. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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