Now showing items 51-60 of 146
Modeling of immunosensors under nonequilibrium conditions : I. Mathematic modeling of performance characteristics
(Elsevier, 1991-08-01)
Immunosensors for the detection of small analytes that use analyte-enzyme conjugates as signal generators require special attention if operated under nonequilibrium conditions. If the size of the analyte and the analyte-enzyme ...
Synthesis of 1-(2-aminopropyl)benzimidazoles, structurally related to the TIBO derivative R82150, with activity against human immunodeficiency virus.
(Elsevier, 1993-04)
A number of 1-(2-aminopropyl)-2-mercaptobenzimidazoles related to the TIBO derivatives R82150 have been prepared and tested for their activity against human immunodeficiency virus type 1 (HIV-1). These compounds were all ...
Regulatory properties of AMP deaminases from rat tissues
(Elsevier, 1991)
1. 1. Phosphoeelluse column chromatography under double gradient conditions (phosphate and KC1) revealed two forms of AMP deaminase in rat heart and brain and a single form in the liver and skeletal muscle.2. 2. Kinetically ...
tRNA-guanine transglycosylase from Escherichia coli: Recognition of dimeric, unmodified tRNATyr
(Elsevier, 1994)
In order to probe the interaction between tRNA and the tRNA hypermodifying enzyme, tRNA-guanine transglycosylase (TGT) from Escherichia coli, we have undertaken the generation of E coli tRNATyr and analogues. During efforts ...
S18.20 Preparation of two kinds of sialic acid specific monomeric monovalent lectin derivatives and their application to the study of cell surface glycoconjugates by flow cytometry
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1993-08)
Isolation of a novel plant lectin with an unusual specificity from Calystegia sepium
(Kluwer Academic Publishers; Chapman and Hall ; Springer Science+Business Media, 1997-01)
A novel plant lectin has been isolated from the rhizomes of Calystegia sepium (hedge bindweed) and partially characterized. The lectin is a dimeric protein composed of two identical non-covalently linked subunits of 16kDa. ...
The interaction of nitrous oxide with cobalamin-dependent methionine synthase
(Elsevier, 1991-08)
Treatment of Gaucher disease with an enzyme inhibitor
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
The hypothesis is offered predicting that Caucher patients could be treated with a drug that slows the synthesis of glucosylceramide, the lipid that accumulates in this disorder. The present therapeutic approach involves ...
Structural requirements for binding to the δ opioid receptor: Alkyl replacements at the third residue of deltorphin I
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1996-01)
The naturally occurring heptapeptide deltorphin I (Tyr- d -Ala-Phe-Asp-Val-Val-Gly-NH 2 ) exhibits extremely high affinity and selectivity for the δ opioid receptor. In an ongoing investigation of the features of this ...
The effects of transforming growth factor alpha and somatostatin on regenerating hepatocytes in the rat
(Elsevier, 1993-03-05)
Transforming growth factor alpha (TGF[alpha]) stimulates DNA synthesis in adult rat hepatocytes, and plays a physiological role after partial hepatectomy by an autocrine mechanism. Somatostatin (SS-14) is a potent inhibitor ...