Now showing items 3321-3330 of 3413
The future of MRI in radiation therapy: Challenges and opportunities for the MR community
(Wiley Periodicals, Inc.ACM, 2022-12)
Radiation therapy is a major component of cancer treatment pathways worldwide. The main aim of this treatment is to achieve tumor control through the delivery of ionizing radiation while preserving healthy tissues for ...
The uptake and utility of genetic testing and genetic counseling for hypertrophic cardiomyopathy—A systematic review and meta-analysis
(R Foundation for Statistical ComputingWiley Periodicals, Inc., 2022-12)
Genetic testing and genetic counseling are routinely indicated for patients with hypertrophic cardiomyopathy (HCM); however, the uptake and utility of these services is not entirely understood. This systematic review and ...
Sex and APOE-ε4 carrier effects on early-onset Alzheimer’s disease pathology
(Wiley Periodicals, Inc., 2022-12)
BackgroundPreviously, we found that female sex is associated with greater pathology burden in early-onset Alzheimer’s disease (EOAD) in the Longitudinal EOAD Study (LEADS). Here, we have expanded our analyses by adding ...
Whole brain MRI-free tau and amyloid PET quantification
(Wiley Periodicals, Inc., 2022-12)
BackgroundThe growing use of PET imaging in Alzheimer’s research and clinical practice has resulted in the need for PET quantification when an MRI is unavailable or contraindicated. The Desikan-Killiany (DK) atlas in ...
Greater social adversity is associated with more disordered eating attitudes and behaviors among children from Southeast Michigan
(John Wiley & Sons, Inc., 2022-12)
ObjectiveThe objective of this study is to examine the association between indicators of social adversity, including socioeconomic status and race/ethnicity, and children’s disordered eating behaviors and attitudes.MethodsChildren ...
Psychotropic medication prescribing in assisted living and nursing home residents with dementia after the National Partnership
(John Wiley & Sons, Inc., 2022-12)
BackgroundThe Centers for Medicare & Medicaid Services implemented the National Partnership to Improve Dementia Care in Nursing Homes (the Partnership) to decrease antipsychotic use and improve care for nursing home (NH) ...
Prevalence of Dementia and Mild Cognitive Impairment in the United States: Findings from the Health and Retirement Study (HRS) Harmonized Cognitive Assessment Protocol (HCAP) Project
(Wiley Periodicals, Inc., 2022-12)
BackgroundNationally representative data are critical for understanding the causes, costs and consequences of dementia and MCI in the US and can better inform policies aimed at reducing their impact on patients, families, ...
Identifying Pathways of Physiological Deterioration to Understand Racial Disparities in Cognitive Status: A 4-way Mediation-Interaction Decomposition Analysis
(Wiley Periodicals, Inc., 2022-12)
BackgroundExposure to interpersonal and structural racism may increase the risk of adverse cognitive aging in racialized groups. Physiological deterioration may lie on the causal pathway leading racism to cognitive aging, ...
Plasma NfL predicts default mode network functional connectivity in older adults at higher risk for Alzheimer’s disease
(Wiley Periodicals, Inc., 2022-12)
BackgroundNeurofilament light (NfL) is a measure of neuronal damage and has the potential as a monitoring and prognostic biomarker of Alzheimer’s disease (AD) (Mattsson et al., 2019). Likewise, alterations in default mode ...
Comparative prevalence of mild cognitive impairment of Alzheimer’s Disease sub-type in Adult Ugandans living with HIV and demographically matched HIV-negative controls
(Wiley Periodicals, Inc., 2022-12)
BackgroundPrevalence rate of mild cognitive impairment (MCI) and Alzheimer’s dementia (AD) in cART treated people living with HIV (PWH) is unknown.Method277 PWH and 189 HIV-negative Ugandan adults matched by age, sex, and ...