Now showing items 21-30 of 53
Combining sequence data from multiple studies: Impact of analysis strategies on rare variant calling and association results
(Wiley Periodicals, Inc., 2020-01)
Individual sequencing studies often have limited sample sizes and so limited power to detect trait associations with rare variants. A common strategy is to aggregate data from multiple studies. For studying rare variants, ...
Semiclassical transition state theory/master equation kinetics of HO + CO: Performance evaluation
(World ScientificWiley Periodicals, Inc., 2020-12)
Previously, master equation (ME) simulations using semiclassical transition state theory (SCTST) and high‐accuracy extrapolated ab initio thermochemistry (HEAT) predicted rate constants in excellent agreement with published ...
Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods
(Wiley‐VCH, 2020-02-21)
Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing
(Wiley Periodicals, Inc., 2020-12)
Chronic macrophage inflammation is a hallmark of type 2 diabetes (T2D) and linked to the development of secondary diabetic complications. T2D is characterized by excess concentrations of saturated fatty acids (SFA) that ...
β‐Mannosylation through O‐Alkylation of Anomeric Cesium Alkoxides: Mechanistic Studies and Synthesis of the Hexasaccharide Core of Complex Fucosylated N‐Linked Glycans
(Wiley Periodicals, Inc.CRC Press, 2020-04-23)
Hydrogen Sulfide Oxidation by Sulfide Quinone Oxidoreductase
(Wiley Periodicals, Inc., 2021-03-16)
Hydrogen sulfide (H2S) is an environmental toxin and a heritage of ancient microbial metabolism that has stimulated new interest following its discovery as a neuromodulator. While many physiological responses have been ...
The role of environmental exposures and the epigenome in health and disease
(John Wiley & Sons, Inc., 2020-01)
Miro: A molecular switch at the center of mitochondrial regulation
(John Wiley & Sons, Inc., 2020-06)
The orchestration of mitochondria within the cell represents a critical aspect of cell biology. At the center of this process is the outer mitochondrial membrane protein, Miro. Miro coordinates diverse cellular processes ...
A pioneer of direct measurements to advance modern gas‐phase chemical kinetics
(Wiley Periodicals, Inc.National Institute of Standards and Technology, 2021-01)