Now showing items 381-390 of 409
Was That a Seizure? Diagnosis in Lived Experience and Medical Practice
(2021)
This dissertation examines how people with epilepsy and physicians make sense of seizure and epilepsy. Seizures are transient phenomena during which people lose control over parts of body-mind function. This can mean the ...
Modeling Dose-Function Response and Toxicity Pathways in Non-Small Cell Lung Cancer Patients Undergoing Radiation Treatment
(2021)
Radiotherapy is currently the standard of care for treating NSCLC patients, and while technological advancements in the field continue to improve our ability to successfully treat these patients, serious side-effects, i.e. ...
A Learning Health Sciences Approach to Understanding Clinical Documentation in Pediatric Rehabilitation Settings
(2020)
The work presented in this dissertation provides an analysis of clinical documentation that challenges the concepts and thinking surrounding missingness of data from clinical settings and the factors that influence why ...
Severe Illness Associated With Respiratory Viruses: Burden and Temporal Dynamics
(2020)
Acute lower respiratory tract infections (ALRI) are a substantial source of global morbidity and mortality, particularly among young children. Respiratory syncytial virus (RSV) and influenza are consistently observed to ...
Targeting the Hsp90 Molecular Chaperone and Resistant Pathways in BRAF-mutant Melanoma
(2020)
Melanoma remains the most aggressive and fatal type of skin cancer. In greater than 50% of cases, patients present with an activating BRAF mutation (BRAF+), leading to upregulated mitogen-activated protein kinase (MAPK) ...
Designing System Support for Sharing Everyday Data for Chronic Care
(2022)
The prevalence of chronic conditions has shifted care settings into private homes. In addition, the increasing availability of physical- and algorithmic-sensing solutions promises large quantities of data about one’s ...
Urinary Continence Recovery After Radical Prostatectomy Using Patient Reported Outcomes Data: Variability, Predictions, and Prediction Accuracy
(2022)
Despite advances in prostate cancer treatment, wide variability in post-operative oncologic and functional outcomes are observed. Effective management of prostate cancer requires accurate prediction of potential outcomes ...
Multiple Chronic Conditions and Post-Stroke Functional Outcome
(2020)
Stroke is a leading cause of disability in the United States (US) and the number of disabled stroke survivors will rise with the aging population. The aging of the US population will also lead to an increase in the prevalence ...
Virtual care is growing, but who will train upcoming learners to practice it?
(Wiley Periodicals, Inc., 2022-12)
Rib cortical bone thickness variation in adults by age and sex
(National Highway Traffic Safety Administration (NHTSA)Wiley Periodicals, Inc., 2022-12)
Rib fractures are a common and serious outcome of blunt thoracic trauma and their likelihood is greater in older individuals. Osteoporotic bone loss is a well-documented aging phenomenon with sex-specific characteristics, ...