Now showing items 91-100 of 121
Computational Discovery of Solid Electrolytes for Batteries: Interfacial Phenomena and Ion Mobility
(2020)
Solid-state batteries (SSBs) using a solid electrolyte (SE) and Li-metal anode are promising technologies that can increase energy density and minimize safety concerns for applications such as electric vehicles. Although ...
Directed Evolution of Stabilized Peptides with Bacterial Display
(2020)
Interactions between proteins govern cellular and the body’s states, including aberrant interactions found in diseases such as in cancers and infections. Small molecule drugs are not ideal in targeting these interactions ...
Development of Scalable Pathways for Addressing Constraints of Emerging Manufacturing Processes
(2023)
The goal of this Ph.D. study was to apply first-principle physics, computational fluid dynamic (CFD) simulation, scientific experimentation, model development and process design to develop scalable pathways for addressing ...
Modeling Pulsed Power Plasmas and Applications to In-situ Nanoparticle Growth
(2022)
Low temperature plasmas (LTPs) have been an essential tool for semiconductor device fabrication. LTPs have been increasingly used in other fields, such as for the synthesis of nanometer sized particles. The prevalence ...
Purely Organic Triplet Emitters: From Fundamental Molecular Design to Performance Amplification in Modern Applications
(2022)
Emissive materials are the essential functional components in many modern and emerging technologies such as organic light-emitting diodes (OLEDs), solid-state lighting, sensors, and data encryption. Metal-free purely organic ...
Development of a Yeast Biosynthetic Platform for Rapid Production and Engineering of an Influenza Virus-like Particle Vaccine
(2020)
Although vaccination is the primary means of preventing influenza virus infection, current influenza vaccines are only moderately effective and do not provide protection against strains with pandemic potential. To overcome ...
Characterizing and Utilizing Droplet-enabled Co-cultivation to Elucidate Interactions in Microbiomes
(2023)
Microbiomes, the collective communities of microorganisms in a particular habitat, play critical roles in host-associated, natural, and built environments. The cell-cell interactions in microbiomes form expansive and complex ...
Computational Study of Emergent Behavior in Active Matter Systems with Particle Shape
(2020)
Murmurations of birds, schools of fish, and herds of migrating animals are macroscale examples of self-propelled units exhibiting emergent collective behavior. We call such systems ``active matter''. On the colloidal scale, ...
Multiscale Modeling of Tuberculosis Disease and Treatment to Optimize Antibiotic Regimens
(2020)
Tuberculosis (TB) is one of the world’s deadliest infectious diseases. Caused by the pathogen Mycobacterium tuberculosis (Mtb), the standard regimen for treating TB consists of treatment with multiple antibiotics for at ...
Systematic Improvement of Quantification and Formulation of Synthetic Protein Nanoparticles for Gene Delivery
(2022)
Gene therapy is a promising field for the generation of new and more effective therapies, but its application is stymied by the lack of safe and efficient delivery vehicles. Furthermore, gene delivery system optimization ...