Now showing items 61-70 of 123
Quantitative analysis of γ‐glutamylisoleucine, γ‐glutamylthreonine, and γ‐glutamylvaline in HeLa cells using UHPLC‐MS/MS
(Wiley Periodicals, Inc., 2021-08)
γ‐Glutamylpeptides have been identified as potential biomarkers for a number of diseases including cancer, diabetes, and liver disease. In this study, we developed and validated a novel quantitative analytical strategy for ...
Current‐Density Regulating Lithium Metal Directional Deposition for Long Cycle‐Life Li Metal Batteries
(Wiley Periodicals, Inc., 2021-08-23)
Uncontrolled dendrite formation in the high energy density of lithium (Li) metal batteries (LMBs) may pose serious safety risks. While numerous studies have attempted to protect separators, these proposed methods fail to ...
Comparison of the MSMS and NanoShaper molecular surface triangulation codes in the TABI Poisson–Boltzmann solver
(John Wiley & Sons, Inc., 2021-08-15)
The Poisson–Boltzmann (PB) implicit solvent model is a popular framework for studying the electrostatics of solvated biomolecules. In this model the dielectric interface between the biomolecule and solvent is often taken ...
Nitric Oxide Release for Enhanced Biocompatibility and Analytical Performance of Implantable Electrochemical Sensors
(Wiley Periodicals, Inc.ASM Press, 2021-09)
The real‐time, continuous monitoring of glucose/lactate, blood gases and electrolytes by implantable electrochemical sensors holds significant value for critically ill and diabetic patients. However, the wide‐spread use ...
Calcium‐Ion Binding Mediates the Reversible Interconversion of Cis and Trans Peroxido Dicopper Cores
(ElsevierWiley Periodicals, Inc., 2021-09-01)
Coupled dinuclear copper oxygen cores (Cu2O2) featured in type III copper proteins (hemocyanin, tyrosinase, catechol oxidase) are vital for O2 transport and substrate oxidation in many organisms. μ‐1,2‐cis peroxido dicopper ...
Toward general regime maps for cohesive‐particle flows: Force versus energy‐based descriptions and relevant dimensionless groups
(John Wiley & Sons, Inc., 2021-09)
Much confusion exists on whether force‐ or energy‐based descriptions of cohesive‐particle interactions are more appropriate. We hypothesize a force‐based description is appropriate when enduring‐contacts dominate and an ...
Synergy and Antagonism between Allosteric and Active‐Site Inhibitors of Abl Tyrosine Kinase
(Wiley Periodicals, Inc., 2021-09-06)
Allosteric inhibitors of Abl kinase are being explored in the clinic, often in combination with ATP‐site inhibitors of Abl kinase. However, there are conflicting data on whether both ATP‐competitive inhibitors and ...
An Open- Shell Coronoid with Hybrid Chichibabin- Schlenk Conjugation
(Wiley Periodicals, Inc., 2021-10-04)
A hexaradicaloid molecule with alternating Kekulé and non- Kekulé connectivities between adjacent spin centers was obtained by fusing two conjugation motifs in Chichibabin and Schlenk hydrocarbons into a coronoid ...
Triggered Reversible Disassembly of an Engineered Protein Nanocage**
(Wiley Periodicals, Inc., 2021-11-15)
Protein nanocages play crucial roles in sub- cellular compartmentalization and spatial control in all domains of life and have been used as biomolecular tools for applications in biocatalysis, drug delivery, and ...
Accelerating the 3D reference interaction site model theory of molecular solvation with treecode summation and cut-offs
(John Wiley & Sons, Inc., 2022-07-05)
The 3D reference interaction site model (3D-RISM) of molecular solvation is a powerful tool for computing the equilibrium thermodynamics and density distributions of solvents, such as water and co-ions, around solute ...